Computers

Protein tertiary structure prediction and refinement using deep learning and Rosetta in CASP14

1 month ago   |   Wiley   |   3 articles

Abstract The trRosetta structure prediction method employs deep learning to generate predicted residue-residue distance and orientation distributions from which 3D models are...
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Bioinformatics Scientist - Medical Genomics Research | Illumina

1 month ago   |   San Diego Biotechnology   |   2 articles

The Bioinformatics group in the Research and Technology Development organization at Illumina is seeking a talented computational scientist to help us develop novel informatics...
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Adapting roots to a hotter planet could ease pressure on food supply

1 month ago   |   Phys

The shoots of plants get all of the glory, with their fruit and flowers and visible structure. But it's the portion that lies below the soil-the branching, reaching arms of...
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Identification of unique subtype-specific interaction features in Class II zinc-dependent HDAC subtype binding pockets: A computational study

1 month ago   |   Journal of Biosciences

Abstract Zinc-dependent HDAC subtypes exhibit differential expression in various cancer types and significantly contribute to oncogenic cell transformation, and hence are...
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Benchmarking of Structure Refinement Methods for Protein Complex Models

1 month ago   |   Wiley

Abstract Protein structure docking is the process in which the quaternary structure of a protein complex is predicted from individual tertiary structures of the protein...
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A Temporal-Spectral-based Squeeze-and-Excitation Feature Fusion Network for Motor Imagery EEG Decoding

1 month ago   |   EMBS

Motor imagery electroencephalography decoding plays an important role in brain-computer interface , which enables motor-disabled patients to communicate with the outside world...
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Antibody Modeling and Epitope Prediction

1 month ago   |   BioMolecular Engineering

Dmitri Beglov, Sandor Vajda, and Dima Kozakov Supported by: NIH R43 GM134769 Software For Antibody Epitope Prediction Accurate epitope prediction is important for the...
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Stochastic Dynamic Modeling of Cellular Protein Interactions

1 month ago   |   BioMolecular Engineering   |   4 articles

Mark Kon, Julio Castrillon, Dmitri Beglov, and Sandor Vajda Supported by: NIH R01GM131409 “Stochastic Dynamic Modeling of Cellular Protein Interactions” NIH R35 GM118078...
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Improving the ClusPro Protein-Protein Docking Server

Improving the ClusPro Protein-Protein Docking Server

1 month ago   |   BioMolecular Engineering   |   4 articles

Sandor Vajda, Dima Kozakov, Ioannis Paschalidis, and Pirooz Vakili Supported by: NIH R35 GM118078 “Analysis and Prediction of Molecular Interactions” NSF DBI 1458509 “ABI...
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Profs. Vajda and Paschalidis featured in Boston University ENGineer magazine

Profs. Vajda and Paschalidis featured in Boston University ENGineer magazine

1 month ago   |   BioMolecular Engineering

The Fall 2019 issue of the BU College of Engineering Magazine highlights the importance of cross-disciplinary collaborations in facilitating scientific discoveries. The title...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

MicroRNA-17-5p Promotes Cardiac Hypertrophy by Targeting Mfn2 to Inhibit...

Abstract Pathological cardiac hypertrophy is the leading cause of heart failure, and miRNAs have been recognized as key factors in cardiac hypertrophy. This study aimed to... Read more ...

Scientist, Hematologic and Immunologic Toxicology - La Jolla, CA - Johnson &...

As part of the cutting-edge Global Predictive, Investigative and Translational Toxicology Team, the candidate will have the opportunity to work within...From Johnson & Johnson... Read more ...

Bringing Protection Back in Line

Bringing Protection Back in Line

Research refines platform to address immune disorders Dr. Esma Yolcu and Dr. Haval Shirwan, Co-pioneers of ProtEx technology By Davis Suppes | Bond LSC The things that protect... Read more ...

After 40 Years, HIV Presents Research Problems New and Old

After 40 Years, HIV Presents Research Problems New and Old

In the years since AIDS was first described in medical research, the scientific map of that disease has changed enormously. Once it was relatively empty. Now scientists... Read more ...

Exosomal circRNA HIPK3 knockdown inhibited cell proliferation and metastasis...

Abstract Prostate cancer is the second frequent malignancy among men in the world. Exosomal circular RNAs have been reported to function in PCa progression. The current study... Read more ...

Prognostic value and immunological characteristics of a novel...

Abstract Autophagy affects the development, progression, and prognosis of various cancers including pancreatic cancer. To develop an autophagy-related prognostic model of... Read more ...

Chiral nanomaterials for tumor therapy: autophagy, apoptosis, and...

Chirality is a fundamental characteristic of natural molecules and a crucial factor in the biochemical reactions of living cells and organisms. Recently, researchers have... Read more ...

Ramil the snow leopard tests positive for COVID at the San Diego Zoo

Zoo staff say the animal's symptoms are mild and are still investigating how he got infected Read more ...

Enhanced lignin biodegradation by consortium of white rot fungi: microbial...

As one of the major components of lignocellulosic biomass, lignin has been considered as the most abundant renewable aromatic feedstock in the world. Comparing with thermal or... Read more ...

Design and heterologous expression of a novel dimeric LL37 variant in Pichia...

The antimicrobial peptide LL37 is produced by white blood cells and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing... Read more ...