Drugs

Rapid production of multimeric RNA aptamers stabilized by a designed pseudo‐circular structure in E. coli

1 day ago   |   Wiley

Abstract RNA aptamers bind specifically and selectively to various macromolecules, cell surfaces and viruses and find broad applications as biosensors, diagnostics, and in...
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AI tailors artificial DNA for future drug development

2 days ago   |   Phys

With the help of an AI, researchers at Chalmers University of Technology, Sweden, have succeeded in designing synthetic DNA that controls the cells' protein production. The...
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Interactions of heparin derivatives with recombinant human keratinocyte growth factor: structural stability and bioactivity effect study

2 days ago   |   Wiley

Abstract Heparin and heparan sulfate are important glycosaminoglycans that can regulate the activities of many vital proteins, especially the fibroblast growth factor family...
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Research Associate, Biology & Protein Chemistry - Plex Pharmaceuticals - San Diego, CA

2 days ago   |   San Diego Biotechnology

Plex Pharmaceuticals , a biotechnology company with a focus on developing novel drugs targeting misfolded and aggregated proteins, has an...From Plex Pharmaceuticals - Fri, 25...
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Scientist, Immunotherapeutic Design - Pfizer - La Jolla, CA

2 days ago   |   San Diego Biotechnology   |   2 articles

Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process...From Pfizer - Fri...
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Biological activity of new bioactive steroids deriving from biotransformation of cortisone

2 days ago   |   Microbial Cell Factories

Cortisone is a metabolite belonging to the corticosteroid class that is used pharmaceutically directly as a drug or prodrug. In addition to its large consumption, its use is...
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Scientist, Discovery Chemistry- Janssen Research & Development, L.L.C - Johnson & Johnson - San Diego, CA

3 days ago   |   San Diego Biotechnology   |   2 articles

The newly formed Discovery Chemistry group is committed to the delivery of high-quality drug candidates working with all six Janssen Therapeutic Areas .From Johnson & Johnson...
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Research Technician - UC San Diego - San Diego, CA

3 days ago   |   San Diego Biotechnology   |   3 articles

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. For the safety and well-being of the entire university...From UC San Diego...
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Scientist II - Eurofins USA BioPharma Services - San Diego, CA

3 days ago   |   San Diego Biotechnology   |   3 articles

Develop, qualify and validate analytical test methods for drug product, intermediates and excipients. Design and execute analytical development studies.From Eurofins USA...
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Research Associate and Lab Manager - UC San Diego - San Diego, CA

3 days ago   |   San Diego Biotechnology   |   5 articles

As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. For the safety and well-being of the entire university... $24.88 - $29.68 an...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Visage Announces Support of Amazon HealthLake Imaging

Visage is working with AWS to streamline and further accelerate access to imaging data with Amazon HealthLake Imaging SAN DIEGO, Nov. 27, 2022 /PRNewswire/ - Visage Imaging... Read more ...

Bio-nanocomplexes with autonomous O2 generation efficiently inhibit triple...

As one kind of aggressive cancer, triple-negative breast cancer has become one of the major causes of women mortality worldwide. Recently, combinational chemo-PDT therapy based... Read more ...

Cellular nanomechanics derived from pattern-dependent focal adhesion and...

Gene transfection was supposed to be the most promising technology to overcome the vast majority of diseases and it has been popularly reported in clinical applications of gene... Read more ...

Toxic effects of trace phenol/guanidine isothiocyanate on cells cultured...

A mixture of phenol and guanidine isothiocyanate (“P/GI”, the principal components of TRIzol™ and similar products) is routinely used to isolate RNA, DNA, and proteins from a... Read more ...

Translational Oncology Lead - Pfizer - La Jolla, CA

Further, these efforts will identify target patient populations with additional focus applied to pharmacodynamic assessments of target engagement and PK/PD...From... Read more ...

An efficient preparation and biocatalytic synthesis of novel...

C-glycosylated flavonoids are a main type of structural modification and can endow flavonoids with greater stability, bioactivity, and bioavailability. Although some... Read more ...

A novel design for biodiesel production from methanol + mutton bone fat mixture

Bioenergy plays a significant role in the green transition. In this work, the conversion of methanol and mutton bone fat oil for bioenergy production was studied. The... Read more ...

Synthesis of nanosize zinc oxide through aqueous sol-gel route in polyol medium

This study is aimed to synthesize nanosize zinc oxide by acid catalyzed sol-gel process using zinc nitrate hexahydrate as precursor, aqueous isopropanol as solvent and glycerin... Read more ...

Synthesis, in silico studies and biological screening of...

A new series of -2--5--4,5-dihydropyrazol-1-yl)benzothiazole derivatives was synthesized and the chemical structures of synthesized compounds were deduced by IR and ... Read more ...

Scientist I, Manufacturing Sciences - Thermo Fisher Scientific - San Diego, CA

Experience in the IVD medical device and/or biotechnology industry is preferred. The Scientist I will support within the Technical Operations Organization in...From Thermo... Read more ...