Gene

Exploration of key residues and conformational change of anti‐terminator protein GlpP for ligand and RNA binding

3 hours ago   |   Wiley   |   2 articles

Abstract Anti‐terminator protein GlpP regulates gene expression of glycerol uptake operon at post‐transcriptional level in a number of bacteria. By now, the molecular dynamics...
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Novartis Gene Therapies: Scientist I, Process Science - Downstream

3 hours ago   |   San Diego Biotechnology

Novartis Gene Therapies: Overview Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological...
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Robust direct digital-to-biological data storage in living cells

9 hours ago   |   ACS Division of Biological Chemistry   |   6 articles

Nature Chemical Biology, Published online: 11 January 2021; doi:10.1038/s41589-020-00711-4 A new DNA data storage technology-data recording in vivo by electrical stimulation...
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A network-based deep learning methodology for stratification of tumor mutations

1 day ago   |   Oxford Journals

AbstractMotivationTumor stratification has a wide range of biomedical and clinical applications, including diagnosis, prognosis and personalized treatment. However, cancer is...
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A two-step approach to testing overall effect of gene-environment interaction for multiple phenotypes

1 day ago   |   Oxford Journals

AbstractMotivationWhile gene-environment interactions contribute importantly to many different phenotypes, detecting such interactions requires well-powered studies and has...
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MendelVar: gene prioritisation at GWAS loci using phenotypic enrichment of mendelian disease genes

1 day ago   |   Oxford Journals

AbstractMotivationGene prioritisation at human GWAS loci is challenging due to linkage disequilibrium and long-range gene regulatory mechanisms. However, identifying the causal...
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Novartis Gene Therapies: Process Science Engineer III - Upstream

2 days ago   |   San Diego Biotechnology

Novartis Gene Therapies: Overview Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological...
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Designer cytokine makes paralyzed mice walk again

2 days ago   |   ScienceDaily

Using gene therapy, a research team has succeeded in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves.
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Looking to build in red-hot viral vector space, Thermo Fisher inks $878M deal for Belgian manufacturer's 2 plants

2 days ago   |   San Diego Biotechnology   |   3 articles

Between Covid-19 vaccines and gene therapies, the contract manufacturing market for viral vector tech has grown at a rapid clip. Thermo Fisher Scientific, already one of the...
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The Use of the Rare TTA Codon in Streptomyces Genes: Significance of the Codon Context?

2 days ago   |   Springer

Abstract Streptomycetes, Gram-positive bacteria with huge and GC-rich genomes provide an ample example of codon usage bias taken to the extreme. Particularly, in all sequenced...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Novartis Gene Therapies: Scientist I, Process Science - Downstream

Novartis Gene Therapies: Overview Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological... Read more ...

Emergent BioSolutions: Scientist

Emergent BioSolutions: Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect... Read more ...

Scientist - Emergent Biosolutions - San Diego, CA

Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect, innovation and...From Emergent... Read more ...

Gilead Sciences, Inc.: Manager, Maintenance

Gilead Sciences, Inc.: Manager, Maintenance United States - California - Oceanside Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers... Read more ...

AnaptysBio, Inc.: Senior Scientist II

AnaptysBio, Inc.: Position Summary The candidate will play a lead role in Protein Sciences, with responsibilities to include the supervision of protein purification an San... Read more ...

Emergent BioSolutions: Senior Manager, Product Development

Emergent BioSolutions: Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect... Read more ...

MendelVar: gene prioritisation at GWAS loci using phenotypic enrichment of...

AbstractMotivationGene prioritisation at human GWAS loci is challenging due to linkage disequilibrium and long-range gene regulatory mechanisms. However, identifying the causal... Read more ...

A two-step approach to testing overall effect of gene-environment...

AbstractMotivationWhile gene-environment interactions contribute importantly to many different phenotypes, detecting such interactions requires well-powered studies and has... Read more ...

A network-based deep learning methodology for stratification of tumor mutations

AbstractMotivationTumor stratification has a wide range of biomedical and clinical applications, including diagnosis, prognosis and personalized treatment. However, cancer is... Read more ...

Recognition of small molecule-RNA binding sites using RNA sequence and structure

AbstractMotivationRNA molecules become attractive small-molecule drug targets to treat disease in recent years. Computer-aided drug design can be facilitated by detecting the... Read more ...