Provide operational support, to include analytical evaluations and prospective clinical evaluations, for diagnostic evaluations, clinical studies, and/or...From General...
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A highly sensitive technique for measuring the state of a cytoskeleton

2 days ago | Phys

A research group from Kumamoto University, Japan has developed a highly sensitive technique to quantitatively evaluate the extent of cytoskeleton bundling from microscopic...
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Impact of explicit area scaling on kinetic models involving multiple compartments

4 days ago | BMC Bioinformatics

Computational modelling of cell biological processes is a frequently used technique to analyse the underlying mechanisms and to generally understand the behaviour of these...
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Preclinical Evaluation of a Novel TALEN Targeting CCR5 Confirms Efficacy and Safety in Conferring Resistance to HIV‐1 Infection

4 days ago | Wiley

Preclinical evaluation of a novel transcription activator‐like effector nuclease to target the C‐C chemokine receptor type 5 locus. Up to 90% of CCR5 alleles are disrupted in...
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Protein over-expression in Escherichia coli triggers adaptation analogous to antimicrobial resistance

4 days ago | Microbial Cell Factories

The E. coli pET system is the most widely used protein over-expression system worldwide. It relies on the assumption that all cells produce target protein and it is generally...
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Model for Rare Cancer Results Instead in Obesity

4 days ago | Discovery's Edge

While a typo in a letter or email is a problem it's not a big one, usually. But when that typo is in genetic code, it's a very different matter. Mayo researchers in the lab of...
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Advances in research on the most general type of stem cells

5 days ago | Phys

Stem cell research is the prerequisite for regenerative medicine, which with the help of the body's cells recreates and heals important organs. Now, researchers at Karolinska...
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Highly selective synthesis of d-amino acids via stereoinversion of corresponding counterpart by an in vivo cascade cell factory

7 days ago | Microbial Cell Factories

D-Amino acids are increasingly used as building blocks to produce pharmaceuticals and fine chemicals. However, establishing a universal biocatalyst for the general synthesis of...
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Effect of overexpression of SNF1 on the transcriptional and metabolic landscape of baker's yeast under freezing stress

8 days ago | Microbial Cell Factories

Freezing stress is the key factor that affecting the cell activity and fermentation performance of baker's yeast in frozen dough production. Generally, cells protect themselves...
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Network approach to mutagenesis sheds insight on phage resistance in mycobacteria

8 days ago | Oxford Journals

AbstractMotivationA rigorous yet general mathematical approach to mutagenesis, especially one capable of delivering systems-level perspectives would be invaluable. Such...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

PacBio and Invitae Team Up to Develop Ultra-High-Throughput Clinical Whole...

The power of PacBio HiFi reads has enabled transformative research into human disease. A new collaboration with Invitae, a leader in medical genetics, is intended to help... Read more ...

STAT: Businesses across the vaccine supply chain must work together to make...

Andrey Zarur, CEO of GreenLight Biosciences, writes for STAT about the vaccine supply chain and how we need to work together to make Covid-19 vaccines. Credit: LEON NEAL/GETTY... Read more ...

IAmScience Leland Cseke

By Becca Wolf | Bond LSC In a cluttered basement in Dearborn, Michigan, one could find Leland Cseke conducting amateur plant tissue culture experiments on his family's pool... Read more ...

Study: X-Rays Surrounding ‘Magnificent 7' May Be Traces of Sought-After Particle

An artistic rendering of the XMM-Newton space telescope. A study of archival data from the XMM-Newton and the Chandra X-ray space telescopes found evidence of high levels of... Read more ...

MendelVar: gene prioritisation at GWAS loci using phenotypic enrichment of...

AbstractMotivationGene prioritisation at human GWAS loci is challenging due to linkage disequilibrium and long-range gene regulatory mechanisms. However, identifying the causal... Read more ...

A two-step approach to testing overall effect of gene-environment...

AbstractMotivationWhile gene-environment interactions contribute importantly to many different phenotypes, detecting such interactions requires well-powered studies and has... Read more ...

A network-based deep learning methodology for stratification of tumor mutations

AbstractMotivationTumor stratification has a wide range of biomedical and clinical applications, including diagnosis, prognosis and personalized treatment. However, cancer is... Read more ...

Recognition of small molecule-RNA binding sites using RNA sequence and structure

AbstractMotivationRNA molecules become attractive small-molecule drug targets to treat disease in recent years. Computer-aided drug design can be facilitated by detecting the... Read more ...

ShinyÉPICo: a graphical pipeline to analyze Illumina DNA methylation arrays

AbstractSummaryIllumina DNA methylation bead arrays provide a cost-effective platform for the simultaneous analysis of a high number of human samples. However, the analysis can... Read more ...

PC2P: Parameter-free network-based prediction of protein complexes

AbstractMotivationPrediction of protein complexes from protein-protein interaction networks is an important problem in systems biology, as they control different cellular... Read more ...