Genes

New 'time machine' technique to measure cells

1 day ago   |   ScienceDaily   |   2 articles

Using a new single-cell technique, researchers have uncovered a way to understand the programming behind how stem cells make particular cell types. The research uncovered new...
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Identification of X-chromosomal genes that drive sex differences in embryonic stem cells through a hierarchical CRISPR screening approach

1 day ago   |   Genome Biology   |   2 articles

X-chromosomal genes contribute to sex differences, in particular during early development, when both X chromosomes are active in females. Double X-dosage shifts female...
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Identification of citrus immune regulators involved in defence against Huanglongbing using a new functional screening system

1 day ago   |   Wiley

Summary Huanglongbing is the most devastating citrus disease in the world. Almost all commercial citrus varieties are susceptible to the causal bacterium, Candidatus...
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Imaging of multiple fluorescent proteins in canopies enables synthetic biology in plants

1 day ago   |   Wiley

Summary Reverse genetics approaches have revolutionized plant biology and agriculture. Phenomics has the prospect of bridging plant phenotypes with genes, including transgenes...
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The celery genome sequence reveals sequential paleo‐polyploidizations, karyotype evolution and resistance gene reduction in apiales

1 day ago   |   Wiley   |   2 articles

Summary Celery , a member of the Apiaceae family, is among the most important and globally grown vegetables. Here, we report a high‐quality genome sequence assembly, anchored...
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A chromosome‐level genome assembly provides insights into ascorbic acid accumulation and fruit softening in guava

1 day ago   |   Wiley   |   2 articles

Summary Guava is an important fleshy‐fruited tree of the Myrtaceae family that is widely cultivated in tropical and subtropical areas of the world and has attracted...
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Overexpression of GmMYB14 improves high‐density yield and drought tolerance of soybean through regulating plant architecture mediated by the brassinosteroid pathway

1 day ago   |   Wiley

Summary MYB transcription factors have been reported to regulate the biosynthesis of secondary metabolites, as well as to mediate plant adaption to abiotic stresses, including...
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Three AP2/ERF family members modulate flavonoid synthesis by regulating type IV chalcone isomerase in citrus

1 day ago   |   Wiley

Summary Flavanones and flavones are excellent source of bioactive compounds but the molecular basis of their highly efficient production remains elusive. Chalcone isomerase...
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Thiopeptides encoding biosynthetic gene clusters mined from bacterial genomes

1 day ago   |   Journal of Biosciences

Abstract Currently, we are at the threshold of the ‘post-antibiotic era' due to the global emergence of antimicrobial resistance , and hence there is a dire need to discover...
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Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer

1 day ago   |   Genome Biology

Muscle-invasive bladder cancers are characterized by their distinct expression of luminal and basal genes, which could be used to predict key clinical features such as disease...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Power of light and oxygen clears Alzheimer's disease protein in live mice

A small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the brains of Alzheimer's disease... Read more ...

Inferring Metal Binding Sites in Flexible Regions of Proteins

ABSTRACT Metal ions are central to the molecular function of many proteins. Thus their knowledge in experimentally determined structure is important; however, such structures... Read more ...

Molecular basis for higher affinity of SARS‐CoV‐2 spike RBD for human ACE2...

Abstract Severe acute respiratory syndrome coronavirus‐2 has caused substantially more infections, deaths, and economic disruptions than the 2002‐2003 SARS‐CoV. The key to... Read more ...

The vaccine rollout is in full swing. What does that mean for COVID testing?

Public health experts say testing remains an important tool in tracking and controlling the spread of the pandemic Read more ...

Glycol chitosan-based tacrolimus-loaded nanomicelle therapy ameliorates...

Recently, we developed hydrophobically modified glycol chitosan nanomicelles loaded with tacrolimus for the targeted renal delivery of TAC. Herein, we determined whether the... Read more ...

Nanoparticle-mediated synergistic chemoimmunotherapy for tailoring cancer...

Nowadays, a potent challenge in cancer treatment is considered the lack of efficacious strategy, which has not been able to significantly reduce mortality. Chemoimmunotherapy... Read more ...

Alginate-chitosan core-shell microcapsule cultures of hepatic cells in a...

A small scale stirred bioreactor was designed and the effect of different agitation rates was investigated on HepG2 cells cultured in alginate-chitosan core-shell microcapsule... Read more ...

Aliphatic extractive effects on acetic acid catalysis of typical...

Xylo-oligosaccharide is the spotlight of functional sugar that improves the economic benefits of lignocellulose biorefinery. Acetic acid acidolysis technology provides a... Read more ...

Multi-omics analysis provides insights into lignocellulosic biomass...

Wood-decay basidiomycetes are effective for the degradation of highly lignified and recalcitrant plant substrates. The degradation of lignocellulosic materials by brown-rot... Read more ...

Lyophilized alginate-based microspheres containing Lactobacillus fermentum...

Lactobacillus fermentum D12 is an exopolysaccharide producing strain whose genome contains a putative eps operon. Whole-genome analysis of D12 was performed to disclose the... Read more ...