Protein

Exploration of key residues and conformational change of anti‐terminator protein GlpP for ligand and RNA binding

1 hour ago | Wiley | 2 articles

Abstract Anti‐terminator protein GlpP regulates gene expression of glycerol uptake operon at post‐transcriptional level in a number of bacteria. By now, the molecular dynamics...
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Robust Principal Component Analysis‐based Prediction of Protein‐Protein Interaction Hot spots

1 hour ago | Wiley | 2 articles

ABSTRACT Proteins often exert their function by binding to other cellular partners. The hot spots are key residues for protein‐protein binding. Their identification may shed...
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Laboratory evolution of a sortase enzyme that modifies amyloid-β protein

8 hours ago | ACS Division of Biological Chemistry | 6 articles

Nature Chemical Biology, Published online: 11 January 2021; doi:10.1038/s41589-020-00706-1 Laboratory evolution of the bacterial transpeptidase sortase A coupled with yeast...
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A cytochrome c is the natural electron acceptor for nicotine oxidoreductase

8 hours ago | ACS Division of Biological Chemistry | 6 articles

Nature Chemical Biology, Published online: 11 January 2021; doi:10.1038/s41589-020-00712-3 Unlike other amine oxidase-family enzymes, nicotine oxidoreductase reacts very slowly...
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AnaptysBio, Inc.: Senior Scientist II

1 day ago | San Diego Biotechnology

AnaptysBio, Inc.: Position Summary The candidate will play a lead role in Protein Sciences, with responsibilities to include the supervision of protein purification an San...
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PC2P: Parameter-free network-based prediction of protein complexes

1 day ago | Oxford Journals

AbstractMotivationPrediction of protein complexes from protein-protein interaction networks is an important problem in systems biology, as they control different cellular...
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A network-based deep learning methodology for stratification of tumor mutations

1 day ago | Oxford Journals

AbstractMotivationTumor stratification has a wide range of biomedical and clinical applications, including diagnosis, prognosis and personalized treatment. However, cancer is...
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Model analyzes how viruses escape the immune system

2 days ago | ScienceDaily

MIT researchers have devised a way to computationally model viral escape, using models that were originally developed to model language. The model can predict which sections of...
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Post Doctoral Scientist - Microbiology - CrossLife Technologies Inc. - Carlsbad, CA

2 days ago | San Diego Biotechnology | 2 articles

She/He will engage in the design and microbial production of protein building blocks that generate innovative materials with programmable patterns,...From Indeed - Fri, 15 Jan...
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Designer cytokine makes paralyzed mice walk again

2 days ago | ScienceDaily

Using gene therapy, a research team has succeeded in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves.
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Novartis Gene Therapies: Scientist I, Process Science - Downstream

Novartis Gene Therapies: Overview Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological... Read more ...

Emergent BioSolutions: Scientist

Emergent BioSolutions: Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect... Read more ...

Scientist - Emergent Biosolutions - San Diego, CA

Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect, innovation and...From Emergent... Read more ...

Gilead Sciences, Inc.: Manager, Maintenance

Gilead Sciences, Inc.: Manager, Maintenance United States - California - Oceanside Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers... Read more ...

AnaptysBio, Inc.: Senior Scientist II

AnaptysBio, Inc.: Position Summary The candidate will play a lead role in Protein Sciences, with responsibilities to include the supervision of protein purification an San... Read more ...

Emergent BioSolutions: Senior Manager, Product Development

Emergent BioSolutions: Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect... Read more ...

MendelVar: gene prioritisation at GWAS loci using phenotypic enrichment of...

AbstractMotivationGene prioritisation at human GWAS loci is challenging due to linkage disequilibrium and long-range gene regulatory mechanisms. However, identifying the causal... Read more ...

A two-step approach to testing overall effect of gene-environment...

AbstractMotivationWhile gene-environment interactions contribute importantly to many different phenotypes, detecting such interactions requires well-powered studies and has... Read more ...

A network-based deep learning methodology for stratification of tumor mutations

AbstractMotivationTumor stratification has a wide range of biomedical and clinical applications, including diagnosis, prognosis and personalized treatment. However, cancer is... Read more ...

Recognition of small molecule-RNA binding sites using RNA sequence and structure

AbstractMotivationRNA molecules become attractive small-molecule drug targets to treat disease in recent years. Computer-aided drug design can be facilitated by detecting the... Read more ...