Therapies

Glycol chitosan-based tacrolimus-loaded nanomicelle therapy ameliorates lupus nephritis

9 hours ago   |   Journal of Nanobiotechnology

Recently, we developed hydrophobically modified glycol chitosan nanomicelles loaded with tacrolimus for the targeted renal delivery of TAC. Herein, we determined whether the...
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Nanoparticle-mediated synergistic chemoimmunotherapy for tailoring cancer therapy: recent advances and perspectives

9 hours ago   |   Journal of Nanobiotechnology

Nowadays, a potent challenge in cancer treatment is considered the lack of efficacious strategy, which has not been able to significantly reduce mortality. Chemoimmunotherapy...
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Senior Scientist, Early Pipeline Development - Novartis Gene Therapies - San Diego, CA

1 day ago   |   San Diego Biotechnology   |   7 articles

Bachelor's Bioprocessing, Biochemical Engineering, or Gene Therapy with 8 years' experience of relevant process development experience in biotechnology/... From Novartis Gene...
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Rapid impedance spectroscopy for monitoring tissue impedance, temperature, and treatment outcome during electroporation-based therapies

2 days ago   |   EMBS

Electroporation-based therapies employ high voltage pulsed electric fields to permeabilize tumor tissue; this results in a detectable impedance change. Impedance...
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Novavax CFO Greg Covino makes a quick exit as leadership carousel keeps turning; Kite execs fly away to a cell therapy upstart teaming up with Lyell

2 days ago   |   San Diego Biotechnology   |   2 articles

Greg Covino? If it seems like Covid-19 vaccine bridesmaid Novavax is shuttling staffers in and out, you're not alone. This week, Greg Covino announced he's leaving the biotech...
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EMA starts review of GSK and Vir's COVID-19 antibody therapy

2 days ago   |   Fierce Biotech   |   2 articles

EMA starts review of GSK and Vir's COVID-19 antibody therapy ntaylor Fri, 04/16/2021 - 06:39
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Scientist/Senior Scientist Autoimmune Disease Thearapy - Sorrento Therapeutics - San Diego, CA

2 days ago   |   San Diego Biotechnology   |   3 articles

Scientist to develop and evaluate candidate therapies for the treatment of autoimmune diseases, such as systemic lupus erythematosus, multiple sclerosis, asthma...From Sorrento...
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Avrobio is using ‘pods' to create gene therapies, and it believes the approach could change the game altogether

3 days ago   |   San Diego Biotechnology

Geoff MacKay Where other companies have gone big, Avrobio is going small. Its manufacturing operation is no different. Instead of trying to keep up with the validation of new...
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In surprising twist, some Alzheimer's plaques may be protective, not destructive

3 days ago   |   San Diego Biotechnology

LA JOLLA-One of the characteristic hallmarks of Alzheimer's disease is the buildup of amyloid-beta plaques in the brain. Most therapies designed to treat AD target these...
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Researchers demonstrate very high specificity of prime editors in plants

3 days ago   |   Phys

Prime editing , a 'search-and-replace' CRISPR-based genome editing technique, has great potential for gene therapy and agriculture. It can introduce desired base conversions...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Power of light and oxygen clears Alzheimer's disease protein in live mice

A small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the brains of Alzheimer's disease... Read more ...

Inferring Metal Binding Sites in Flexible Regions of Proteins

ABSTRACT Metal ions are central to the molecular function of many proteins. Thus their knowledge in experimentally determined structure is important; however, such structures... Read more ...

Molecular basis for higher affinity of SARS‐CoV‐2 spike RBD for human ACE2...

Abstract Severe acute respiratory syndrome coronavirus‐2 has caused substantially more infections, deaths, and economic disruptions than the 2002‐2003 SARS‐CoV. The key to... Read more ...

The vaccine rollout is in full swing. What does that mean for COVID testing?

Public health experts say testing remains an important tool in tracking and controlling the spread of the pandemic Read more ...

Glycol chitosan-based tacrolimus-loaded nanomicelle therapy ameliorates...

Recently, we developed hydrophobically modified glycol chitosan nanomicelles loaded with tacrolimus for the targeted renal delivery of TAC. Herein, we determined whether the... Read more ...

Nanoparticle-mediated synergistic chemoimmunotherapy for tailoring cancer...

Nowadays, a potent challenge in cancer treatment is considered the lack of efficacious strategy, which has not been able to significantly reduce mortality. Chemoimmunotherapy... Read more ...

Alginate-chitosan core-shell microcapsule cultures of hepatic cells in a...

A small scale stirred bioreactor was designed and the effect of different agitation rates was investigated on HepG2 cells cultured in alginate-chitosan core-shell microcapsule... Read more ...

Aliphatic extractive effects on acetic acid catalysis of typical...

Xylo-oligosaccharide is the spotlight of functional sugar that improves the economic benefits of lignocellulose biorefinery. Acetic acid acidolysis technology provides a... Read more ...

Multi-omics analysis provides insights into lignocellulosic biomass...

Wood-decay basidiomycetes are effective for the degradation of highly lignified and recalcitrant plant substrates. The degradation of lignocellulosic materials by brown-rot... Read more ...

Lyophilized alginate-based microspheres containing Lactobacillus fermentum...

Lactobacillus fermentum D12 is an exopolysaccharide producing strain whose genome contains a putative eps operon. Whole-genome analysis of D12 was performed to disclose the... Read more ...