Chemical

Crossing boundaries

5 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00795-6 Crossing boundaries
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Designing stable DNAzymes

5 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00796-5 Designing stable DNAzymes
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Guiding light

5 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00794-7 Guiding light
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Focal assembly

5 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00797-4 Focal assembly
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Engineering AraC to make it responsive to light instead of arabinose

5 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00787-6 Engineering of a blue light-inducible AraC dimerization system in E. coli permits light-dependent, rather than arabinose-based, regulation of gene expression from standard PBAD promoters, enabling temporal and spatial control of bacterial systems.
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A stop sign for RAS trafficking

5 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 29 April 2021; doi:10.1038/s41589-021-00789-4 N-Ras lipidation cycling is known to regulate its trafficking and function. A new S-depalmitoylation inhibitor induces N-Ras membrane mislocalization, providing insights into N-Ras function and laying the foundation for a new cancer therapeutic strategy.
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ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth

5 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 29 April 2021; doi:10.1038/s41589-021-00785-8 ABD957 is a potent and selective inhibitor of the ABHD17 family of depalmitoylases that disrupts N-Ras signaling in human acute myeloid leukemia cells and can synergize with MEK inhibition.
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Susan Bukata, MD, Named Chair of the Department of Orthopaedic Surgery

Bukata is only the fourth woman in the U.S. to lead a health system's orthopedic surgery department. Read more ...

A trait of the rare few whose bodies naturally control HIV: 'trained' immune...

Scientists have discover that 'elite controllers' have myeloid dendritic cells that display characteristics of trained innate immune cells. Read more ...

How mitochondria make the cut

With the help of their custom-built super-resolution microscope, biophysicists have discovered where and why mitochondria divide, putting to rest controversy about the... Read more ...

Sustained delivery of MMP-9 siRNA via thermosensitive hydrogel accelerates...

Excessive expression of matrix metalloproteinase 9 impedes healing of diabetic chronic wounds, thus wound dressing that could effectively inhibit the expression of MMP-9 offers... Read more ...

The unpredictable carbon nanotube biocorona and a functionalization method...

The intrinsic physicochemical properties of carbon nanotubes make them unique tools in nanotechnology. Their elemental composition, resilience, thermal properties, and surface... Read more ...

Enhancement of doxorubicin anti-cancer activity by vascular targeting using...

Gold nanospheres tagged with peptides containing isoDGR , an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor... Read more ...

Immune response induced by oral administration with a Saccharomyces...

The global pandemic of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 highlights the need to develop safe and effective vaccines with a top... Read more ...

Thin, Large-Area Device Converts Infrared Light into Images

An infrared imager developed by UC San Diego engineers could be used to see through smog and fog; easily locate blood vessels on a patient; and see through silicon wafers to... Read more ...

Blanks for the Memory

UC San Diego researchers report that one kind of perceptual learning can occur in memory-impaired persons who do not actually remember what they learned. Read more ...

Wishbone Day Raises Awareness of Osteogenesis Imperfecta

Today, May 6th, is Wishbone Day , to raise awareness about osteogenesis imperfecta . Also known as “brittle bone disease,” OI is a consequence of mutations that disrupt the... Read more ...