Brain

Circ 0003423 Alleviates ox-LDL-Induced Human Brain Microvascular Endothelial Cell Injury via the miR-589-5p/TET2 Network

8 days ago   |   By Springer

Abstract
Brain microvascular endothelial cells injury is one of the main causes of cerebrovascular diseases. Circular RNA has been found to be involved in the regulation of cerebrovascular diseases progression. However, the role and mechanism of circ 0003423 in cerebrovascular diseases is still unclear. In our study, oxidized low density lipoprotein -induced HBMEC-IM cells were used to construct cerebrovascular cell injury model in vitro. Quantitative real-time PCR was used to determine the expression levels of circ 0003423, miR-589-5p and Ten-eleven translocation 2. The interactions...
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