Chemical

Crossing boundaries

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00795-6 Crossing boundaries
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Designing stable DNAzymes

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00796-5 Designing stable DNAzymes
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Guiding light

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00794-7 Guiding light
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Focal assembly

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00797-4 Focal assembly
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Engineering AraC to make it responsive to light instead of arabinose

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 26 April 2021; doi:10.1038/s41589-021-00787-6 Engineering of a blue light-inducible AraC dimerization system in E. coli permits light-dependent, rather than arabinose-based, regulation of gene expression from standard PBAD promoters, enabling temporal and spatial control of bacterial systems.
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A stop sign for RAS trafficking

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 29 April 2021; doi:10.1038/s41589-021-00789-4 N-Ras lipidation cycling is known to regulate its trafficking and function. A new S-depalmitoylation inhibitor induces N-Ras membrane mislocalization, providing insights into N-Ras function and laying the foundation for a new cancer therapeutic strategy.
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ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 29 April 2021; doi:10.1038/s41589-021-00785-8 ABD957 is a potent and selective inhibitor of the ABHD17 family of depalmitoylases that disrupts N-Ras signaling in human acute myeloid leukemia cells and can synergize with MEK inhibition.
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Process for eliminating unneeded cells may also protect against cancer

Biologists find cell extrusion, a process that helps organisms eliminated unneeded cells, is triggered when cells can't replicate their DNA during cell division. In humans... Read more ...

New bonobo genome fine tunes great ape evolution studies

A new, high-quality bonobo genome assembly has been constructed. It is allowing scientists to more accurately compare the bonobo genome to that of other great apes - the... Read more ...

Director of Finance - Janux Therapeutics, Inc. - San Diego, CA

Janux is developing unique immunotherapies that generate tumor-specific immune responses to attack and kill tumors without destroying a patient's healthy tissue... $47,448... Read more ...

Resident Immune Cells Nurse Brain Cells after Seizure

Resident Immune Cells Nurse Brain Cells after Seizure

Mayo Clinic researchers have found evidence that a type of resident immune cell in the brain helps protect neurons after seizures. Their results, published in Cell Reports... Read more ...

Macrophage Communication is Key During Viral Infection

Macrophage Communication is Key During Viral Infection

A new finding from Mayo Clinic researchers and colleagues may suggest treatment options for severe viral infections and new avenues for research into tissue regeneration after... Read more ...

Expelling cancer by squeezing out rogue cells

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CVS now offering walk-in coronavirus vaccination at pharmacies in San Diego...

The pharmacy chain is also offering same-day appointment scheduling Read more ...

Cymbiotika Introduces Rya Organics for Its Market-leading CBD Products

SAN DIEGO-- CBD-Cymbiotika, a leading nutritional supplement brand known for creating pure, clinically backed supplements, announces the launch of Rya Organics. Read more ...

Synthesis, biological evaluation and docking studies of 1,2,4-oxadiazole...

1,2,4-oxadiazole derivatives exhibited significant anti-cancer activity when they were evaluated, against human cancer cell lines. They also showed anti-inflammatory... Read more ...

Manager, Site Operations | Astellas

Job Description Developing innovative therapies is one of the most challenging, most essential and personally rewarding fields in science. This is the most exciting time to be... Read more ...