Chemical

Launching the missile

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00683-5 Launching the missile
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It's a trap!

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00680-8 It's a trap!
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Advanced rules of relays

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-0632-8 Transfer of ubiquitin onto target proteins requires controlled interplay between E2 conjugating enzymes and E3 ligases. The structure of a trapped E2~Ub/RCR E3 transfer intermediate provides novel insight into the diversity of mechanisms used to fine tune this relay.
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Hijacking protein degradation

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00685-3 Targeted protein degradation provides a powerful complement to small-molecule inhibition in modulating protein activity and allows access to otherwise intractable drug targets.
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Clarifying the translational potential of B-I09

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00654-w Clarifying the translational potential of B-I09
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Kinase ins and outs

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00682-6 Kinase ins and outs
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Reversal of nucleobase methylation by dioxygenases

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00675-5 This Review summarizes the chemical and physical properties of methylated nucleobases in DNA and RNA, proposes a chemical classification of methylation types, and discusses recent advance in demethylation reactions mediated by dioxygenases.
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Fine-tuning adhesives

4 days ago   |   By ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00681-7 Fine-tuning adhesives
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Explicación sobre estudios de terapias experimentales contra la COVID-19

Explicación sobre estudios de terapias experimentales contra la COVID-19

Según queda claro después de meses de pandemia, la COVID-19 afecta a la gente de varias maneras. Algunos pueden infectarse y no presentar síntomas , mientras otros tienen... Read more ...

Toxic Cellular Ooze Linked to Biological Age, Disease and Disability

Toxic Cellular Ooze Linked to Biological Age, Disease and Disability

Cells in the body usually do what they're told. In response to cues, cells divide, grow, shrink or die as needed. But there are some cells that start to ignore the body's order... Read more ...

Aging and Immune Decline: Destiny or Dynamic?

Aging and Immune Decline: Destiny or Dynamic?

Aging is typically linked with the point in time when it causes problems. But there are many types of aging. There's chronological age, which we celebrate each year, sometimes... Read more ...

Berkeley Lab Building Efficiency Campaign Drives $95M in Annual Energy Savings

Berkeley Lab Building Efficiency Campaign Drives $95M in Annual Energy Savings

By Natalie Pawelski One hundred and four U.S. companies, schools, governments, and institutions are taking their building energy savings to a new level with the Department of... Read more ...

Chasing Their Tails but Getting Somewhere: Reimagining the Shape of Noise...

Chasing Their Tails but Getting Somewhere: Reimagining the Shape of Noise Leads to Improved Molecular Models

Univ. of Tennessee undergrad Elliot Perryman worked with Biosciences staff scientist Peter Zwart during his fall 2019 Berkeley Lab Undergraduate Research internship. Tenacity... Read more ...

WFH Series: Kestrel McCorkle

WFH Series: Kestrel McCorkle

As we navigate this interesting time of working from home, we asked a few GreenLighter's what their tips and tricks are staying inspired and connected with co-workers. This... Read more ...

Associate Scientist, Biologics Analytical Operations, Oceanside, CA - Gilead...

Gilead provides a work environment free of harassment and prohibited conduct. Demonstrate ability to learn new techniques/knowledge quickly.From Indeed - Wed, 21 Oct 2020... Read more ...

Emergent BioSolutions: Specialist I, QA

Emergent BioSolutions: Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect... Read more ...

Repairing the photosynthetic enzyme Rubisco

Manajit Hayer-Hartl, head of the research group "Chaperonin-assisted Protein Folding," has a long-standing interest in the central enzyme of photosynthesis called Rubisco. Her... Read more ...

Integrative analysis of key candidate genes and signaling pathways in...

Summary Cytotoxic T lymphocyte-associated antigen-4 , the first immune checkpoint to be targeted clinically, has provided an effective treatment option for various... Read more ...