Gene

The HiFi difference: resolving the most complex genomic regions

4 days ago   |   By Pacific Biosciences

The combined accuracy, read length, and coverage uniformity of PacBio HiFi sequence reads enables the characterization of many previously inaccessible regions in the genome. Two new preprints by Oscar Rodriguez, William Gibson, Melissa Smith, Corey Watson and collaborators describe the use of HiFi sequencing to illuminate immunoglobulins , providing another powerful demonstration of how much there is still to discover and learn about human genomes. The studies also demonstrate the use of targeted HiFi sequencing best practices to study regions of interest at low cost and with high...
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