Genomics

New technique combines single-cell and metagenomic analyses to characterize microbes

2 days ago   |   By ScienceDaily

Metagenomic analysis has greatly advanced our understanding of the complex human microbiome without the need for extensive bacterial isolation and culturing. However, metagenome-assembled genomes may be imprecise and insufficiently differentiate closely related species. Now, researchers have developed a novel integrated framework that combines conventional metagenomics and single-cell genomics and can complement the lacunae in each approach, thus yielding better genome recovery and accurate resolution of complex microbial populations.
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