Bioinformatics

GCRNN: graph convolutional recurrent neural network for compound-protein interaction prediction

14 days ago   |   By BMC Bioinformatics

Compound-protein interaction prediction is necessary to investigate health regulatory functions and promotes drug discovery. Machine learning is becoming increasingly important in bioinformatics for applicatio...
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Unprecedented multiscale model of protein behavior linked to cancer-causing mutations

14 days ago   |   By Phys

Lawrence Livermore National Laboratory researchers and a multi-institutional team of scientists have developed a highly detailed, machine learning-backed multiscale model revealing the importance of lipids to the signaling dynamics of RAS, a family of proteins whose mutations are linked to numerous cancers.
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Scientists use Summit supercomputer, deep learning to predict protein functions at genome scale

14 days ago   |   By Phys

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

An unexpected attraction of nucleic acids and fat

All cells on Earth are enveloped in a fatty layer of lipids. Lipid membranes protect the content of the cells, including genetic information such as RNA and DNA. A new study... Read more ...

Designed SARS‐CoV‐2 receptor binding domain variants form stable monomers

Abstract The receptor binding domain of the SARS-CoV-2 spike -protein is a prime target of virus-neutralizing antibodies present in convalescent sera of COVID-19 patients and... Read more ...

Engineering Acetobacterium woodii for the production of isopropanol and...

Abstract The capability of four genetically modified A. woodii strains for improved production of acetone from CO 2 and hydrogen was tested. The acetone biosynthesis pathway... Read more ...

L‐Lactate oxidase‐mediated removal of L‐lactic acid derived from...

Abstract Background : There has been an increasing demand for optically pure D-lactic and L-lactic acid for the production of stereocomplex-type polylactic acid. The D-lactic... Read more ...

Structure‐based discovery of small molecules improving stability of human...

Abstract The production of biopharmaceuticals in engineered plant-based systems is a promising technology that has proven its suitability for the production of various... Read more ...

Leaf Angle: A Target of Genetic Improvement in Cereal Crops Tailored for...

Summary High-density planting is an effective measure for increasing crop yield per unit land area. Leaf angle is a key trait of plant architecture and a target for genetic... Read more ...

Ontology-based identification and prioritization of candidate drugs for...

Drug repurposing can improve the return of investment as it finds new uses for existing drugs. Literature-based analyses exploit factual knowledge on drugs and diseases, e.g... Read more ...

Proliferation and differentiation of primary bovine myoblasts using...

Abstract Recently, cultured meat obtained from livestock-derived cells is being considered as a sustainable food source that reduces the use of natural resources. This study... Read more ...

Novel modified culture medium for enhancing redifferentiation of...

Abstract The dedifferentiation of articular chondrocytes during in vitro expansion deteriorates the hyaline cartilage regeneration. Many approaches have been developed to... Read more ...

UFGI Publication Round-up: Week of 1/24/22

Mitogen-Activated Protein Kinase 4-Regulated Metabolic Networks. Lin C, Lott AA, Zhu W, Dufresne CP, Chen S. Int J Mol Sci. 2022 Jan 14;23(2):880. doi... Read more ...