Tissue
Upregulation of long noncoding RNA XIST has anticancer effects on ovarian cancer through sponging miR-106a
15 days ago | By Springer
Abstract
Ovarian cancer is a highly malignant tumor. X inactive specific transcript was identified as a cancer-related gene, while its therapeutic effect in OC was poorly defined. The present study was designed to investigate the effectual corollary of the lncRNA XIST in OC. RT-qPCR was used to detect the XIST and miR-106a expression levels of OC tissues and cell lines. OC cell apoptosis and proliferation were detected by flow cytometry, colony formation, and CCK-8 assays. Moreover, bioinformatics analysis was used to predict the targeted miRNA of XIST. The dual-luciferase reporter and RNA...
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An immune-related risk gene signature predicts the prognosis of breast cancer
15 days ago | By Springer
Abstract
Background
Accurate prediction of the outcome of breast cancer remains as a challenge due to its heterogeneous nature. We aimed to construct an immune-related risk signature to predict the overall outcome of breast cancer using bioinformatic approaches.
Methods
In this study, transcriptome and survival data obtained from The Cancer Genome Atlas database and the Gene Expression Omnibus database were used to identify differentially expressed genes between breast cancer and normal samples. A regulatory network was constructed based on the immune-related prognostic genes and...
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Tissue Bioinformatic Therapeutics Cancer Bioinformatics RNA Gene Genes Nature Genomics Immunity GenomeWorld Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
2nd International Conference on Tissue Science and Regenerative Medicine
This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...
Latin America Expansion
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LightCUD: a program for diagnosing IBD based on human gut microbiome data
The diagnosis of inflammatory bowel disease and discrimination between the types of IBD are clinically important. IBD is associated with marked changes in the intestinal... Read more ...
Comparing various protocols of human and bovine ovarian tissue...
Nowadays, the number of cancer survivors is significantly increasing as a result of efficient chemo/radio therapeutic treatments. Female cancer survivors may suffer from... Read more ...
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Multienzymes activity of metals and metal oxide nanomaterials: applications...
With the rapid advancement and progress of nanotechnology, nanomaterials with enzyme-like catalytic activity have fascinated the remarkable attention of researchers, due to... Read more ...
Modular vaccine platform based on the norovirus-like particle
Virus-like particle vaccines have recently emerged as a safe and effective alternative to conventional vaccine technologies. The strong immunogenic effects of VLPs can be... Read more ...
Few-layer graphene induces both primary and secondary genotoxicity in...
Toxicological evaluation of engineered nanomaterials is essential for occupational health and safety, particularly where bulk manufactured ENMs such as few-layer graphene are... Read more ...
FAO Promotes Innovation to Maintain Agri-Food Systems During the COVID-19...
Innovative approaches in agri-food systems were used by households and countries to help minimize the impact of the COVID-19 pandemic on food supply chains. More innovative... Read more ...