Tissue

Circ 0002711 knockdown suppresses cell growth and aerobic glycolysis by modulating miR-1244/ROCK1 axis in ovarian cancer

10 days ago   |   By Journal of Biosciences

Abstract
It has been well investigated that circular RNAs play important roles in various cancers. The function of circ 0002711 and its underlying mechanisms in ovarian cancer remain unknown. qRT-PCR and western blot were performed to detect the expressions of circ 0002711, microRNA-1244 , and Rho kinase 1 in OC tissues and cells. MTT assay and colony formation assay were employed to evaluate cell proliferation. Detection of lactate production, glucose uptake, and ATP level and oxygen consumption were used to determine Warburg effect. Western blot was used to examine glycolysis or...
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Circ-HIPK3 regulates YAP1 expression by sponging miR-381-3p to promote oral squamous cell carcinoma development

10 days ago   |   By Journal of Biosciences

Abstract
Circular RNAs have been reported to play important roles in human cancers. Circular RNA homeodomain interacting protein kinase 3 was investigated to be involved in tumorigenesis. However, the functions of circ-HIPK3 in oral squamous cell carcinoma remain vague. The expression of circ-HIPK3, microRNA -381-3p and Yes-associated protein1 was detected by qRT-PCR or western blot. Cell proliferation, apoptosis, invasion and migration were measured by MTT assay, flow cytometry, or transwell assay. The dual-luciferase reporter assay was employed to test the target correlations miR-381-3p...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

The role of the gut microbiota on the metabolic status of obese children

The term “metabolically healthy obese ” denotes a hale and salutary status, yet this connotation has not been validated in children, and may, in fact, be a misnomer. As... Read more ...

Role of Snf-β in lipid accumulation in the high lipid‐producing fungus Mucor...

Mucor circinelloides WJ11 is a high-lipid producing strain and an excellent producer of γ-linolenic acid which is crucial for human health. We have previously identified genes... Read more ...

Targeting hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase for...

Hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase is a central enzyme of the so-called “esters” pathway to monolignols. As originally envisioned, HCT functions twice... Read more ...

Increased expression of fatty acid and ABC transporters enhances seed oil...

Lipid transporters play an essential role in lipid delivery and distribution, but their influence on seed oil production in oilseed crops is not well studied. Read more ...

Colorimetric LPMO assay with direct implication for cellulolytic activity

Lytic polysaccharide monooxygenases are important industrial enzymes known for their catalytic degradation of recalcitrant polymers such as cellulose or chitin. Their activity... Read more ...

Novartis Gene Therapies: Senior Manager, Process Science - Operations

Novartis Gene Therapies: Overview Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological... Read more ...

Ambrx, Inc.: Clinical Operations Director

Ambrx, Inc.: Ambrx Inc., is a clinical-stage biopharmaceutical company focused on developing Precision Biologics using an expanded genetic code. Ambrx technology La Jolla, CA... Read more ...

CNN: Critical component for Covid-19 vaccines is in short supply

CNN: Critical component for Covid-19 vaccines is in short supply

GreenLight Biosciences is mentioned in a CNN report on the short supply of key ingredients for Covid-19 vaccines. GreenLight Biosciences is mentioned in a CNN report on the... Read more ...

Retroviruses are re-writing the koala genome and causing cancer

Koalas are facing multiple environmental and health issues which threaten their survival. Along with habitat loss - accelerated by last year's devastating bush fires - domestic... Read more ...

Using the Power of Genomics to Find Answers for Rare Disease Patients and...

Using the Power of Genomics to Find Answers for Rare Disease Patients and Families

Sunday is Rare Disease Day - a time to honor the patients, families, caregivers, and healthcare professionals who are part of the rare disease community.  At PacBio, we are... Read more ...