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BMC Bioinformatics

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GENTLE: A NOVEL BIOINFORMATICS TOOL FOR GENERATING FEATURES AND BUILDING CLASSIFIERS FROM T CELL REPERTOIRE CANCER DATA

In the global effort to discover biomarkers for cancer prognosis, prediction tools have become essential resources. TCR repertoires...

ION-PUMPING MICROBIAL RHODOPSIN PROTEIN CLASSIFICATION BY MACHINE LEARNING APPROACH

Rhodopsin is a seven-transmembrane protein covalently linked with retinal chromophore that absorbs photons for energy conversion and...

 
 
 

DETECTING GENOMIC DELETIONS FROM HIGH-THROUGHPUT SEQUENCE DATA WITH UNSUPERVISED LEARNING

DEEPSELECTNET: DEEP NEURAL NETWORK BASED SELECTIVE SEQUENCING FOR OXFORD NANOPORE SEQUENCING

Nanopore sequencing allows selective sequencing, the ability to programmatically reject unwanted reads in a sample. Selective sequencing...

 
 
 

GDAPHEN, R PIPELINE TO IDENTIFY THE MOST IMPORTANT QUALITATIVE AND QUANTITATIVE PREDICTOR VARIABLES FROM PHENOTYPIC DATA

In individuals or animals suffering from genetic or acquired diseases, it is important to identify which clinical or phenotypic variables...

SINGLE-CELL SPATIAL EXPLORER: EASY EXPLORATION OF SPATIAL AND MULTIMODAL TRANSCRIPTOMICS

The development of single-cell technologies yields large datasets of information as diverse and multimodal as transcriptomes, immunophenotypes,...

 
 
 

EFFECTIVE MATRIX DESIGNS FOR COVID-19 GROUP TESTING

Grouping samples with low prevalence of positives into pools and testing these pools can achieve considerable savings in testing resources...

NF-CORE/CIRCRNA: A PORTABLE WORKFLOW FOR THE QUANTIFICATION, MIRNA TARGET PREDICTION AND DIFFERENTIAL EXPRESSION ANALYSIS OF CIRCULAR RNAS

Circular RNAs are a class of covalenty closed non-coding RNAs that have garnered increased attention from the research community due...

 
 
 

IDENTIFICATION OF PROGNOSTIC AND PREDICTIVE BIOMARKERS IN HIGH-DIMENSIONAL DATA WITH PPLASSO

In clinical trials, identification of prognostic and predictive biomarkers has became essential to precision medicine. Prognostic biomarkers...

ACCOMMODATING MULTIPLE POTENTIAL NORMALIZATIONS IN MICROBIOME ASSOCIATIONS STUDIES

Microbial communities are known to be closely related to many diseases, such as obesity and HIV, and it is of interest to identify...

 
 
 

SVHOUND: DETECTION OF REGIONS THAT HARBOR YET UNDETECTED STRUCTURAL VARIATION

Recent population studies are ever growing in number of samples to investigate the diversity of a population or species. These studies...

BADASS: BACTERIOCIN-DIVERSITY ASSESSMENT SOFTWARE

Bacteriocins are defined as thermolabile peptides produced by bacteria with biological activity against taxonomically related species....

 
 
 

MULTISCALE-CNN-4MCPRED: A MULTI-SCALE CNN AND ADAPTIVE EMBEDDING-BASED METHOD FOR MOUSE GENOME DNA N4-METHYLCYTOSINE PREDICTION

N4-methylcytosine is an important epigenetic mechanism, which regulates many cellular processes such as cell differentiation and gene...

PDA-PRGCN: IDENTIFICATION OF PIWI-INTERACTING RNA-DISEASE ASSOCIATIONS THROUGH SUBGRAPH PROJECTION AND RESIDUAL SCALING-BASED FEATURE AUGMENTATION

Emerging evidences show that Piwi-interacting RNAs play a pivotal role in numerous complex human diseases. Identifying potential piRNA-disease...

 
 
 

GENOMIC AND IMMUNOGENOMIC ANALYSIS OF THREE PROGNOSTIC SIGNATURE GENES IN LUAD

Searching for immunotherapy-related markers is an important research content to screen for target populations suitable for immunotherapy....

A SIGNATURE OF IMMUNE-RELATED GENES CORRELATING WITH CLINICAL PROGNOSIS AND IMMUNE MICROENVIRONMENT IN SEPSIS

Immune-related genes remain poorly understood in their function in the onset and progression of sepsis.

 
 
 

IDENTIFICATION OF BIOMARKERS PREDICTIVE OF METASTASIS DEVELOPMENT IN EARLY-STAGE COLORECTAL CANCER USING NETWORK-BASED REGULARIZATION

Colorectal cancer is the third most common cancer and the second most deathly worldwide. It is a very heterogeneous disease that can...

IDENTIFYING CANCER DRIVER GENES BASED ON MULTI-VIEW HETEROGENEOUS GRAPH CONVOLUTIONAL NETWORK AND SELF-ATTENTION MECHANISM

Correctly identifying the driver genes that promote cell growth can significantly assist drug design, cancer diagnosis and treatment....

 
 
 

XCORE: AN R PACKAGE FOR INFERENCE OF GENE EXPRESSION REGULATORS

Elucidating the Transcription Factors that drive the gene expression changes in a given experiment is a common question asked by researchers....

CORRECTION: A LIGHTWEIGHT CLASSIFICATION OF ADAPTOR PROTEINS USING TRANSFORMER NETWORKS

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Scientists are trying to resurrect the dodo centuries after the bird...

The list of extinct species that genetic engineering company Colossal wants to bring back to life is growing. The latest addition: the dodo. Read more ...

Six Berkeley Lab Scientists Named AAAS Fellows

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New software enables automated analysis of biomedical image data without...

The software JIPipe was developed by scientists at the Leibniz Institute for Natural Product Research and Infection Biology and significantly simplifies the analysis of images... Read more ...

Changes in hippocampal volume during a preceding 10-year period do not...

Abstract Hippocampal blood-brain barrier permeability may increase in normal healthy ageing and contribute to neurodegenerative disease. To examine this hypothesis, we... Read more ...

Morusin and mulberrin extend the lifespans of yeast and C. elegans via...

Abstract Compounds with lifespan extension activity are rare, although increasing research efforts have been invested in this field to find ways to extend healthy lifespan. By... Read more ...

GENTLE: a novel bioinformatics tool for generating features and building...

In the global effort to discover biomarkers for cancer prognosis, prediction tools have become essential resources. TCR repertoires contain important features that... Read more ...

NAD+ supplementation improves mAb productivity in CHO cells via a glucose...

Abstract Aerobic glycolysis and its by-product lactate accumulation are usually associated with adverse culture phenotypes such as poor cell viability and productivity. Due to... Read more ...

BSN 2023 - Call for Papers is Open!

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Associations between physical activity and cognitive dysfunction in older...

Abstract Canine cognitive dysfunction is a form of dementia that shares many similarities with Alzheimer's disease. Given that physical activity is believed to reduce risk of... Read more ...

Xylotrechus smei : a potential threat to red sanders cultivation

Abstract Red sanders is an economically important, endangered timber species endemic to the restricted forest tracts of the Eastern Ghats, India. Here, we report the occurrence... Read more ...