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BMC Bioinformatics

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2-D CHEMICAL STRUCTURE IMAGE-BASED IN SILICO MODEL TO PREDICT AGONIST ACTIVITY FOR ANDROGEN RECEPTOR

Abnormal activation of human nuclear hormone receptors disrupts endocrine systems and thereby affects human health. There have been...

LITERATURE MINING FOR CONTEXT-SPECIFIC MOLECULAR RELATIONS USING MULTIMODAL REPRESENTATIONS

Biological contextual information helps understand various phenomena occurring in the biological systems consisting of complex molecular...

 
 
 

LITERATURE BASED DISCOVERY OF ALTERNATIVE TCM MEDICINE FOR ADVERSE REACTIONS TO DEPRESSION DRUGS

In recent years, Traditional Chinese Medicine and alternative medicine have been widely used along with western drugs as a complementary...

CORRECTION TO: DEEP USER IDENTIFICATION MODEL WITH MULTIPLE BIOMETRIC DATA

An amendment to this paper has been published and can be accessed via the original article.

 
 
 

CALCULATING THE MOST LIKELY INTRON SPLICING ORDERS IN S. POMBE, FRUIT FLY, ARABIDOPSIS THALIANA, AND HUMANS

Introns have been shown to be spliced in a defined order, and this order influences both alternative splicing regulation and splicing...

A RANK-BASED MARKER SELECTION METHOD FOR HIGH THROUGHPUT SCRNA-SEQ DATA

High throughput microfluidic protocols in single cell RNA sequencing collect mRNA counts from up to one million individual cells in...

 
 
 

NIMBUS: A NEGATIVE BINOMIAL REGRESSION BASED INTEGRATIVE METHOD FOR MUTATION BURDEN ANALYSIS

Identifying frequently mutated regions is a key approach to discover DNA elements influencing cancer progression. However, it is challenging...

NCMHAP: A NOVEL METHOD FOR HAPLOTYPE RECONSTRUCTION BASED ON NEUTROSOPHIC C-MEANS CLUSTERING

Single individual haplotype problem refers to reconstructing haplotypes of an individual based on several input fragments sequenced...

 
 
 

PYGNA: A UNIFIED FRAMEWORK FOR GENESET NETWORK ANALYSIS

Gene and protein interaction experiments provide unique opportunities to study the molecular wiring of a cell. Integrating high-throughput...

DIFFERENTIAL GENE REGULATORY PATTERN IN THE HUMAN BRAIN FROM SCHIZOPHRENIA USING TRANSCRIPTOMIC-CAUSAL NETWORK

Common and complex traits are the consequence of the interaction and regulation of multiple genes simultaneously, therefore characterizing...

 
 
 

PREDICTING MIRNA-DISEASE ASSOCIATIONS BY MULTIPLE META-PATHS FUSION GRAPH EMBEDDING MODEL

Many studies prove that miRNAs have significant roles in diagnosing and treating complex human diseases. However, conventional biological...

METALAFFA: A FLEXIBLE, END-TO-END, DISTRIBUTED COMPUTING-COMPATIBLE METAGENOMIC FUNCTIONAL ANNOTATION PIPELINE

Microbial communities have become an important subject of research across multiple disciplines in recent years. These communities are...

 
 
 

USING OPTIMAL CONTROL TO UNDERSTAND COMPLEX METABOLIC PATHWAYS

Optimality principles have been used to explain the structure and behavior of living matter at different levels of organization, from...

A METHOD FOR ESTIMATING COHERENCE OF MOLECULAR MECHANISMS IN MAJOR HUMAN DISEASE AND TRAITS

Phenotypes such as height and intelligence, are thought to be a product of the collective effects of multiple phenotype-associated...

 
 
 

CANCER PROGNOSIS PREDICTION USING SOMATIC POINT MUTATION AND COPY NUMBER VARIATION DATA: A COMPARISON OF GENE-LEVEL AND PATHWAY-BASED MODELS

Genomic profiling of solid human tumors by projects such as The Cancer Genome Atlas has provided important information regarding the...

CDKAM: A TAXONOMIC CLASSIFICATION TOOL USING DISCRIMINATIVE K-MERS AND APPROXIMATE MATCHING STRATEGIES

Current taxonomic classification tools use exact string matching algorithms that are effective to tackle the data from the next generation...

 
 
 

REPAHR: AN IMPROVED APPROACH FOR DE NOVO REPEAT IDENTIFICATION BY ASSEMBLY OF THE HIGH-FREQUENCY READS

Repetitive sequences account for a large proportion of eukaryotes genomes. Identification of repetitive sequences plays a significant...

SEARCH AND COMPARISON OF GENOMIC FEATURE PATTERNS IN MULTIPLE GENOME BROWSER TRACKS

Genome browsers are widely used for locating interesting genomic regions, but their interactive use is obviously limited to inspecting...

 
 
 

OPOSSOM-BROWSER: AN INTERACTIVE TOOL TO EXPLORE OMICS DATA LANDSCAPES IN HEALTH SCIENCE

OposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses,...

IMPLEMENTATION OF HOMOLOGY BASED AND NON-HOMOLOGY BASED COMPUTATIONAL METHODS FOR THE IDENTIFICATION AND ANNOTATION OF ORPHAN ENZYMES: USING MYCOBACTERIUM TUBERCULOSIS H37RV AS A CASE STUDY

Homology based methods are one of the most important and widely used approaches for functional annotation of high-throughput microbial...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Four months in, Baker lab hits the ground running and won't be stopping...

Four months in, Baker lab hits the ground running and won't be stopping anytime soon

Post doctorate Harim Tavares from the Baker lab works in “the hood,” which is a space used to prevent researchers and other outside factors from contaminating cells. By Lauren... Read more ...

IAmScience Karl Kerns

IAmScience Karl Kerns

By Becca Wolf | Bond LSC It's all about the journey and Karl Kerns has been places. Originally from a small town in southwestern Iowa, Kerns did his undergrad years at Iowa... Read more ...

IAmScience Alana Rodney

IAmScience Alana Rodney

By Lauren Hines | Bond LSC Research assistant Alana Rodney walked into her high school science class a few years ago expecting to fill another credit. However, it was there... Read more ...

Regulators Classify Gene-Edited Rice Varieties with Disease Resistance as...

Regulators Classify Gene-Edited Rice Varieties with Disease Resistance as Equivalent to Conventional Varieties

Crops resist bacterial leaf blight; ruling clears path to provide smallholder farmers with a safe, affordable option for preventing destructive disease A farmer works on paddy... Read more ...

Finding a Link between Xenoestrogens and Autism

Finding a Link between Xenoestrogens and Autism

California mice | photo by Roger Meissen, Bond LSC By Becca Wolf | Bond LSC It's hard to see a family member treated differently because of a behavior disorder, but those with... Read more ...

IAmScience Norma Castro-Guerrero

IAmScience Norma Castro-Guerrero

By Becca Wolf | Bond LSC If you like your work, you won't ever work a day in your life. That's the case for Norma Castro-Guerrero, a research scientist in David Mendoza's lab... Read more ...

Plant vs. Pathogen

Plant vs. Pathogen

Research scientist Jianbin Su studies the immune system in lettuce on the third floor of the Bond Life Science Center. By Lauren Hines | Bond LSC Scientist Jianbin Su's... Read more ...

Influenza: How it Transmits from Birds to Pigs

Influenza: How it Transmits from Birds to Pigs

Henry Wan | Photo by Roger Meissen, Bond LSC By Becca Wolf Geese will soon fill the skies as they migrate south in V-formation as the weather gets colder and the leaves start... Read more ...

Beyond the Vaccine

Beyond the Vaccine

Lucas Woods from the Weisman lab watches lung cancer cells and oral epithelial cells grow. | photo by Lauren Hines, Bond LSC By Lauren Hines | Bond LSC Vaccine development... Read more ...

Egyptian Genome Added to Growing List of Population-Specific Reference Genomes

Egyptian Genome Added to Growing List of Population-Specific Reference Genomes

We're excited to report that another team has used PacBio long-read sequencing to produce a population-specific reference genome - this time an Egyptian genome that should... Read more ...