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BMC Bioinformatics

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TMBED: TRANSMEMBRANE PROTEINS PREDICTED THROUGH LANGUAGE MODEL EMBEDDINGS

Despite the immense importance of transmembrane proteins for molecular biology and medicine, experimental 3D structures for TMPs remain...

DEVELOPMENT AND VALIDATION OF THE POTENTIAL BIOMARKERS BASED ON M6A-RELATED LNCRNAS FOR THE PREDICTIONS OF OVERALL SURVIVAL IN THE LUNG ADENOCARCINOMA AND DIFFERENTIAL ANALYSIS WITH CUPROPTOSIS

The treatment and prognosis of lung adenocarcinoma remains a challenge. The study aimed to conduct a systematic analysis of the predictive...

 
 
 

SMASH: A SCALABLE, GENERAL MARKER GENE IDENTIFICATION FRAMEWORK FOR SINGLE-CELL RNA-SEQUENCING

Single-cell RNA-sequencing is revolutionising the study of cellular and tissue-wide heterogeneity in a large number of biological scenarios,...

ELIMINATOR: ESSENTIALITY ANALYSIS USING MULTISYSTEM NETWORKS AND INTEGER PROGRAMMING

A gene is considered as essential when it is indispensable for cells to grow and replicate in a certain environment. However, gene...

 
 
 

RISK SCORE PREDICTION MODEL BASED ON SINGLE NUCLEOTIDE POLYMORPHISM FOR PREDICTING MALARIA: A MACHINE LEARNING APPROACH

The malaria risk prediction is currently limited to using advanced statistical methods, such as time series and cluster analysis on...

IMPROVED PREDICTION OF GENE EXPRESSION THROUGH INTEGRATING CELL SIGNALLING MODELS WITH MACHINE LEARNING

A key problem in bioinformatics is that of predicting gene expression levels. There are two broad approaches: use of mechanistic models...

 
 
 

IN-SILICO DESIGN OF AN IMMUNOINFORMATICS BASED MULTI-EPITOPE VACCINE AGAINST LEISHMANIA DONOVANI

Visceral Leishmaniasis is a fatal vector-borne parasitic disorder occurring mainly in tropical and subtropical regions. VL falls under...

FUSED INVERSE-NORMAL METHOD FOR INTEGRATED DIFFERENTIAL EXPRESSION ANALYSIS OF RNA-SEQ DATA

Use of next-generation sequencing technologies to transcriptomics for gene expression profiling has found widespread application in...

 
 
 

DAGBAGM: LEARNING DIRECTED ACYCLIC GRAPHS OF MIXED VARIABLES WITH AN APPLICATION TO IDENTIFY PROTEIN BIOMARKERS FOR TREATMENT RESPONSE IN OVARIAN CANCER

Applying directed acyclic graph models to proteogenomic data has been shown effective for detecting causal biomarkers of complex diseases....

CRANET: A COMPREHENSIVE RESIDUAL ATTENTION NETWORK FOR INTRACRANIAL ANEURYSM IMAGE CLASSIFICATION

Rupture of intracranial aneurysm is the first cause of subarachnoid hemorrhage, second only to cerebral thrombosis and hypertensive...

 
 
 

COGITO: AUTOMATED AND GENERIC COMPARISON OF ANNOTATED GENOMIC INTERVALS

Genetic and epigenetic biological studies often combine different types of experiments and multiple conditions. While the corresponding...

IMPUTACCUR: FAST AND USER-FRIENDLY CALCULATION OF GENOTYPE-IMPUTATION ACCURACY-MEASURES

ImputAccur is a software tool to measure genotype-imputation accuracy. Imputation of untyped markers is a standard approach in genome-wide...

 
 
 

SEMPLME: A TOOL FOR INTEGRATING DNA METHYLATION EFFECTS IN TRANSCRIPTION FACTOR BINDING AFFINITY PREDICTIONS

Aberrant DNA methylation in transcription factor binding sites has been shown to lead to anomalous gene regulation that is strongly...

A DEEP LEARNING FRAMEWORK FOR IDENTIFYING ESSENTIAL PROTEINS BASED ON MULTIPLE BIOLOGICAL INFORMATION

Essential Proteins are demonstrated to exert vital functions on cellular processes and are indispensable for the survival and reproduction...

 
 
 

MULTI-SCALED SELF-ATTENTION FOR DRUG-TARGET INTERACTION PREDICTION BASED ON MULTI-GRANULARITY REPRESENTATION

Drug-target interaction prediction plays a crucial role in drug discovery. Although the advanced deep learning has shown promising...

IN SILICO DESIGN OF A MULTI-EPITOPE VACCINE AGAINST HPV16/18

Cervical cancer is the fourth most common cancer affecting women and is caused by human Papillomavirus infections that are sexually...

 
 
 

MULTIPLE ROLES OF APOLIPOPROTEIN B MRNA EDITING ENZYME CATALYTIC SUBUNIT 3B IN HUMAN TUMORS: A PAN-CANCER ANALYSIS

Although there have been some recent cell and animal experiments indicating that expression of the gene encoding apolipoprotein B mRNA...

INVESTIGATION OF DIRIGENT LIKE DOMAINS FROM BACTERIAL GENOMES

DIRs are mysterious protein that have the ability to scavenge free radicals, which, are highly reactive with molecules in their vicinity....

 
 
 

JOINT ANALYSIS OF SCATAC-SEQ DATASETS USING EPICONV

Technical improvement in ATAC-seq makes it possible for high throughput profiling the chromatin states of single cells. However, data...

FCFDR: AN R PACKAGE TO LEVERAGE CONTINUOUS AND BINARY FUNCTIONAL GENOMIC DATA IN GWAS

Genome-wide association studies are limited in power to detect associations that exceed the stringent genome-wide significance threshold....

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

See-through zebrafish, new imaging method put blood stem cells in...

For the first time, researchers can get a high-resolution view of single blood stem cells thanks to a little help from microscopy and zebrafish. Read more ...

Technology Transfer Associate II - Argonaut Manufacturing Services...

An understanding of LEAN practices and the use of continuous improvement tools like Kaizen, 5 why's, fishbone diagrams, DMAIC, poka... Read more ...

Delay-Dependent Stability Analysis of Interfered Digital Filters with...

Abstract This work investigates stability of interfered digital filters with time-varying delay and saturation overflow arithmetic. A criterion is proposed to guarantee... Read more ...

High Energy Efficiency and Linearity Switching Scheme Without Reset Energy...

Abstract A high energy efficiency and linearity switching scheme is proposed for the successive approximation register analog-to-digital converter. With the tri-level switching... Read more ...

Research team models moving 'washers' that help DNA replicate

Knowing the structure of a complex biological system isn't nearly enough to understand how it works. It helps to know how the system moves. Read more ...

Petco evolves organizational design to enable next phase of growth

SAN DIEGO, Aug. 9, 2022 /PRNewswire/ - Petco Health and Wellness Company, Inc. today announced an evolution in its organizational design and new roles to enable continued... Read more ...

Research Assitant - CrossLife Technologies Inc. - Carlsbad, CA

Strong experience in molecular biology including standard cloning techniques, vector design, sequence analysis, DNA and RNA extraction, cDNA synthesis,...From Indeed... Read more ...

CT scanner captures entire wooly mammoth tusk

For the first time, researchers successfully captured CT images of an entire wooly mammoth tusk, according to a new "Images in Radiology" article published in the journal... Read more ...

Buyer II - Salk Institute for Biological Studies - San Diego, CA

Prior experience in a biotechnology or nonprofit academic research environment. Procures laboratory and administrative supplies and services within the level of...From Salk... Read more ...

Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability

CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry... Read more ...