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Microbial Cell Factories

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PROTEIN OVER-EXPRESSION IN ESCHERICHIA COLI TRIGGERS ADAPTATION ANALOGOUS TO ANTIMICROBIAL RESISTANCE

The E. coli pET system is the most widely used protein over-expression system worldwide. It relies on the assumption that all cells...

MOLECULAR, STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF A NOVEL RECOMBINANT CHLOROPHYLLASE FROM CYANOBACTERIUM OSCILLATORIA ACUMINATA PCC 6304

Chlorophyllase catalyzes the hydrolysis of chlorophyll and produces chlorophyllide and phytol. Cyanobacterial chlorophyllases are likely...

 
 
 

HIGHLY SELECTIVE SYNTHESIS OF D-AMINO ACIDS VIA STEREOINVERSION OF CORRESPONDING COUNTERPART BY AN IN VIVO CASCADE CELL FACTORY

D-Amino acids are increasingly used as building blocks to produce pharmaceuticals and fine chemicals. However, establishing a universal...

QUANTITATIVE PROTEOMIC ANALYSIS TO REVEAL EXPRESSION DIFFERENCES FOR BUTANOL PRODUCTION FROM GLYCEROL AND GLUCOSE BY CLOSTRIDIUM SP. STRAIN CT7

Clostridium sp. strain CT7 is a new emerging microbial cell factory with high butanol production ratio owing to its non-traditional...

 
 
 

STUDY ON THE ISOPRENE-PRODUCING CO-CULTURE SYSTEM OF SYNECHOCOCCUS ELONGATES-ESCHERICHIA COLI THROUGH OMICS ANALYSIS

The majority of microbial fermentations are currently performed in the batch or fed-batch manner with the high process complexity and...

IMPROVED PRODUCTION OF GERMACRENE A, A DIRECT PRECURSOR OF SS-ELEMENE, IN ENGINEERED SACCHAROMYCES CEREVISIAE BY EXPRESSING A CYANOBACTERIAL GERMACRENE A SYNTHASE

The sesquiterpene germacrene A is a direct precursor of ß-elemene that is a major component of the Chinese medicinal herb Curcuma wenyujin...

 
 
 

EFFECTIVE PRODUCTION OF HUMAN GROWTH FACTORS IN ESCHERICHIA COLI BY FUSING WITH SMALL PROTEIN 6HFH8

Growth factors are signaling proteins that affect cellular processes such as growth, proliferation, and differentiation. GFs are used...

EFFECT OF OVEREXPRESSION OF SNF1 ON THE TRANSCRIPTIONAL AND METABOLIC LANDSCAPE OF BAKER'S YEAST UNDER FREEZING STRESS

Freezing stress is the key factor that affecting the cell activity and fermentation performance of baker's yeast in frozen dough production....

 
 
 

WHOLE GENOME SEQUENCING AND METABOLOMICS ANALYSES REVEAL THE BIOSYNTHESIS OF NEROL IN A MULTI-STRESS-TOLERANT MEYEROZYMA GUILLIERMONDII GXDK6

Nerol , an acyclic monoterpene, naturally presents in plant essential oils, and is used widely in food, cosmetics and pharmaceuticals...

THE DAMAGE AND TOLERANCE MECHANISMS OF PHAFFIA RHODOZYMA MUTANT STRAIN MK19 GROWN AT 28 °C

Phaffia rhodozyma has many desirable properties for astaxanthin production, including rapid heterotrophic metabolism and high cell...

 
 
 

HETEROLOGOUS EXPRESSION OF PHANEROCHAETE CHRYSOSPORIUM CELLOBIOSE DEHYDROGENASE IN TRICHODERMA REESEI

Cellobiose dehydrogenase from Phanerochaete chrysosporium is a key enzyme in lignocellulose depolymerization, biosensors and biofuel...

CONSTRUCTION AND CHARACTERIZATION OF A NOVEL GLUCOSE DEHYDROGENASE-LEUCINE DEHYDROGENASE FUSION ENZYME FOR THE BIOSYNTHESIS OF L-TERT-LEUCINE

Biosynthesis of l-tert-leucine , a significant pharmaceutical intermediate, by a cofactor regeneration system friendly and efficiently...

 
 
 

RHAMNOLIPID THE GLYCOLIPID BIOSURFACTANT: EMERGING TRENDS AND PROMISING STRATEGIES IN THE FIELD OF BIOTECHNOLOGY AND BIOMEDICINE

Rhamnolipids are surface-active compounds and belong to the class of glycolipid biosurfactants, mainly produced from Pseudomonas aeruginosa....

MAXIMIZING PHB CONTENT IN SYNECHOCYSTIS SP. PCC 6803: A NEW METABOLIC ENGINEERING STRATEGY BASED ON THE REGULATOR PIRC

PHB represents a promising bioplastic alternative with good biodegradation properties. Furthermore, PHB can be produced in a completely...

 
 
 

HETEROLOGOUS EXPRESSION OF THE ATYPICAL TETRACYCLINE CHELOCARDIN REVEALS THE FULL SET OF GENES REQUIRED FOR ITS BIOSYNTHESIS

Chelocardin exhibits a broad-spectrum antibiotic activity and showed promising results in a small phase II clinical study conducted...

MANIPULATING THE POSITION OF DNA EXPRESSION CASSETTES USING LOCATION TAGS FUSED TO DCAS9 TO IMPROVE METABOLIC PATHWAY EFFICIENCY

Deactivated Cas9 led to significant improvement of CRISPR/Cas9-based techniques because it can be fused with a variety of functional...

 
 
 

EXPRESSING A CYTOSOLIC PYRUVATE DEHYDROGENASE COMPLEX TO INCREASE FREE FATTY ACID PRODUCTION IN SACCHAROMYCES CEREVISIAE

Saccharomyces cerevisiae is being exploited as a cell factory to produce fatty acids and their derivatives as biofuels. Previous studies...

DESIGNING NEXT GENERATION RECOMBINANT PROTEIN EXPRESSION PLATFORMS BY MODULATING THE CELLULAR STRESS RESPONSE IN ESCHERICHIA COLI

A cellular stress response is triggered upon recombinant protein synthesis which acts as a global feedback regulator of protein expression....

 
 
 

ENGINEERING THE CALVIN-BENSON-BASSHAM CYCLE AND HYDROGEN UTILIZATION PATHWAY OF RALSTONIA EUTROPHA FOR IMPROVED AUTOTROPHIC GROWTH AND POLYHYDROXYBUTYRATE PRODUCTION

CO2 is fixed by all living organisms with an autotrophic metabolism, among which the Calvin-Benson-Bassham cycle is the most important...

ENGINEERING LACTOCOCCUS LACTIS AS A MULTI-STRESS TOLERANT BIOSYNTHETIC CHASSIS BY DELETING THE PROPHAGE-RELATED FRAGMENT

In bioengineering, growth of microorganisms is limited because of environmental and industrial stresses during fermentation. This study...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

FT: Vaccine makers race to fix vaccine supply issues

FT: Vaccine makers race to fix vaccine supply issues

GreenLight Biosciences explain to the Financial Times the vaccine supply issues for a Covid-19 vaccine. GreenLight Biosciences spoke to the Financial Times about the vaccine... Read more ...

Primer on Carbon Dioxide Removal Provides Vital Resource at Critical Time

Primer on Carbon Dioxide Removal Provides Vital Resource at Critical Time

Berkeley Lab researchers are working on ways to sequester more carbon in soil, including through agricultural practices. Scientists say that any serious plan to address... Read more ...

A 1-Atom-Deep Look at a Water-Splitting Catalyst

A 1-Atom-Deep Look at a Water-Splitting Catalyst

This illustration shows two possible types of surface layers for a catalyst that performs the water-splitting reaction, the first step in making hydrogen fuel: The gray surface... Read more ...

New Research Technique Sheds Light on Least Understood Part of Lithium Batteries

New Research Technique Sheds Light on Least Understood Part of Lithium Batteries

A scientist works on the MALDI (matrix-assisted laser desorption/ionization) mass spectrometer at Berkeley Lab's Molecular Foundry. One of the aspects of lithium-ion batteries... Read more ...

Ozone Generators May Help Remediate Contamination Caused by Thirdhand Smoke

Ozone Generators May Help Remediate Contamination Caused by Thirdhand Smoke

Residue from cigarettes can linger on indoor surfaces for years and even decades. In 10 years of studying thirdhand smoke, which is the toxic cigarette residue that clings to... Read more ...

Financial Times: Get vaccine new variant ready

Financial Times: Get vaccine new variant ready

GreenLight Biosciences explain to the Financial Times how messenger RNA can help get the Covid-19 vaccine new variant ready. GreenLight Biosciences spoke to the Financial Times... Read more ...

Shine On: Avalanching Nanoparticles Break Barriers to Imaging Cells in Real Time

Shine On: Avalanching Nanoparticles Break Barriers to Imaging Cells in Real Time

From left: Experimental images of thulium-doped avalanching nanoparticles separated by 300 nanometers; at right, simulations of the same material. (Credit: Berkeley Lab and... Read more ...

How a gene linked to the circadian clock could point to new prostate cancer...

How a gene linked to the circadian clock could point to new prostate cancer treatments arlene.weintraub Fri, 01/15/2021 - 08:15 Read more ...

Sinopharm claims COVID-19 vaccine safe in kids aged 3 and up

Sinopharm claims COVID-19 vaccine safe in kids aged 3 and up ntaylor Fri, 01/15/2021 - 07:49 Read more ...

Ex-Merck scientist accused of stealing trade secrets on Keytruda, raising...

Ex-Merck scientist accused of stealing trade secrets on Keytruda, raising threat of 10-year prison term ntaylor Fri, 01/15/2021 - 05:49 Read more ...