ISOLATION OF A NOVEL DNA APTAMER AGAINST LIPL32 AS A POTENTIAL DIAGNOSTIC AGENT FOR THE DETECTION OF PATHOGENIC LEPTOSPIRA

Abstract Leptospirosis is a potentially life-threatening zoonosis caused by pathogenic Leptospira and for rapid diagnostics, direct...

METHODS FOR ADDRESSING HOST CELL PROTEIN IMPURITIES IN BIOPHARMACEUTICAL PRODUCT DEVELOPMENT

Abstract The high demand for monoclonal antibody therapeutics in recent years has resulted in significant efforts to improve their...

 
 
 

RAPID PRODUCTION OF MULTIMERIC RNA APTAMERS STABILIZED BY A DESIGNED PSEUDO‐CIRCULAR STRUCTURE IN E. COLI

Abstract RNA aptamers bind specifically and selectively to various macromolecules, cell surfaces and viruses and find broad applications...

MINI‐ AND MACRO‐SCALE DIRECT PERFUSION BIOREACTORS WITH OPTIMIZED FLOW FOR ENGINEERING 3D TISSUES

Abstract Bioreactors enabling direct perfusion of cell suspensions or culture media through the pores of 3D scaffolds have long been...

 
 
 

A SIMPLIFIED DIRECT ON‐CHIP FORWARD OR REVERSE IMMUNOASSAY FOR EVALUATING PROTEIN‐PROTEIN INTERACTIONS IN THE SERUM

Abstract Background The identification of protein-protein interactions is a great challenge. In this study, we fabricated a gold surface-modified...

SODIUM FORMATE REDIRECTS CARBON FLUX AND ENHANCES HETEROLOGOUS MEVALONATE PRODUCTION IN METHYLOBACTERIUM EXTORQUENS AM1

Abstract Methylobacterium extorquens AM1 , a model strain of methylotrophic cell factories could be used to produce fine chemicals...

 
 
 

IMMOBILIZATION OF ARG‐GLY‐ASP PEPTIDES ON SILK FIBROIN VIA GLY‐ALA‐GLY‐ALA‐GLY‐SER SEQUENCES

Abstract A simple method by which the functional peptide of Gly-Arg-Gly-Asp-Ser is immobilized on the surface of silk fibroin films...

INTERACTIONS OF HEPARIN DERIVATIVES WITH RECOMBINANT HUMAN KERATINOCYTE GROWTH FACTOR: STRUCTURAL STABILITY AND BIOACTIVITY EFFECT STUDY

Abstract Heparin and heparan sulfate are important glycosaminoglycans that can regulate the activities of many vital proteins, especially...

 
 
 

UNDERSTANDING THE IN SILICO ASPECTS OF BACTERIAL CATABOLIC CASCADE FOR STYRENE DEGRADATION

Abstract Styrene is a non-polar organic compound used in very high-volume for the industrial scale production of commercially important...

A SINGLE‐CELL SURGERY MICROFLUIDIC DEVICE FOR TRANSPLANTING TUMOR CYTOPLASM INTO DENDRITIC CELLS WITHOUT NUCLEI MIXING

Abstract This study aimed to demonstrate the feasibility of generating tumor cell vaccine models by single-cell surgery in a microfluidic...

 
 
 

A NOVEL PLANT‐MADE MONOCLONAL ANTIBODY ENHANCES THE SYNERGETIC POTENCY OF AN ANTIBODY COCKTAIL AGAINST THE SARS‐COV‐2 OMICRON VARIANT

Summary Abstract This study describes a novel, neutralizing monoclonal antibody , 11D7, discovered by mouse immunization and hybridoma...

CRISPR‐INDUCED MIRNA156‐RECOGNITION ELEMENT MUTATIONS IN TASPL13 IMPROVE MULTIPLE AGRONOMIC TRAITS IN WHEAT

Summary Summary Increase of grain yield is always a major objective of wheat genetic improvement. The SQUAMOSA-promoter binding protein-like...

 
 
 

IN SILICO MODELLING HUMAN VPS13 PROTEINS ASSOCIATED WITH DONOR AND TARGET MEMBRANES SUGGESTS LIPID TRANSFER MECHANISMS

Abstract The VPS13 protein family constitutes a novel class of bridge-like lipid transferases. Autosomal recessive inheritance of mutations...

TRANSCRIPTOME ANALYSIS OF SF9 INSECT CELLS DURING PRODUCTION OF RECOMBINANT ADENO‐ASSOCIATED VIRUS

Abstract The insect cell-baculovirus expression vector system has emerged as an alternative time- and cost-efficient production platform...

 
 
 

SEQUENCING OF CAMELINA NEGLECTA, A DIPLOID PROGENITOR OF THE HEXAPLOID OILSEED CAMELINA SATIVA

Summary Camelina neglecta is a diploid species from the genus Camelina, which includes the versatile oilseed Camelina sativa. These...

ISSUE INFORMATION

Front cover image: The upper panel are photo of rice plants showing developmental traits, and the bottom-panel are rice blast lesions...

 
 
 

A POLLEN EXPRESSED PME GENE AT TCB1 LOCUS CONFERS MAIZE UNILATERAL CROSS‐INCOMPATIBILITY

Plant Biotechnology Journal, Accepted Article.

UPGRADING THE GENOME OF AN ELITE JAPONICA RICE VARIETY KONGYU 131 FOR LODGING RESISTANCE IMPROVEMENT

Summary Developing a new rice variety requires tremendous efforts and years of input. To improve the defect traits of the excellent...

 
 
 

ENHANCING GENE EDITING AND GENE TARGETING EFFICIENCIES IN ARABIDOPSIS THALIANA BY USING AN INTRON‐CONTAINING VERSION OF TTLBCAS12A

Plant Biotechnology Journal, Accepted Article.

COEXPRESSION OF TWO DESATURASES PROVIDES OPTIMIZED REDUCTION OF SATURATES IN CAMELINA OIL

Summary Reducing the saturate content of vegetable oils is key to increasing their utility and adoption as a feedstock for the production...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Visage Announces Support of Amazon HealthLake Imaging

Visage is working with AWS to streamline and further accelerate access to imaging data with Amazon HealthLake Imaging SAN DIEGO, Nov. 27, 2022 /PRNewswire/ - Visage Imaging... Read more ...

Bio-nanocomplexes with autonomous O2 generation efficiently inhibit triple...

As one kind of aggressive cancer, triple-negative breast cancer has become one of the major causes of women mortality worldwide. Recently, combinational chemo-PDT therapy based... Read more ...

Cellular nanomechanics derived from pattern-dependent focal adhesion and...

Gene transfection was supposed to be the most promising technology to overcome the vast majority of diseases and it has been popularly reported in clinical applications of gene... Read more ...

Toxic effects of trace phenol/guanidine isothiocyanate on cells cultured...

A mixture of phenol and guanidine isothiocyanate (“P/GI”, the principal components of TRIzol™ and similar products) is routinely used to isolate RNA, DNA, and proteins from a... Read more ...

Translational Oncology Lead - Pfizer - La Jolla, CA

Further, these efforts will identify target patient populations with additional focus applied to pharmacodynamic assessments of target engagement and PK/PD...From... Read more ...

An efficient preparation and biocatalytic synthesis of novel...

C-glycosylated flavonoids are a main type of structural modification and can endow flavonoids with greater stability, bioactivity, and bioavailability. Although some... Read more ...

A novel design for biodiesel production from methanol + mutton bone fat mixture

Bioenergy plays a significant role in the green transition. In this work, the conversion of methanol and mutton bone fat oil for bioenergy production was studied. The... Read more ...

Synthesis of nanosize zinc oxide through aqueous sol-gel route in polyol medium

This study is aimed to synthesize nanosize zinc oxide by acid catalyzed sol-gel process using zinc nitrate hexahydrate as precursor, aqueous isopropanol as solvent and glycerin... Read more ...

Synthesis, in silico studies and biological screening of...

A new series of -2--5--4,5-dihydropyrazol-1-yl)benzothiazole derivatives was synthesized and the chemical structures of synthesized compounds were deduced by IR and ... Read more ...

Scientist I, Manufacturing Sciences - Thermo Fisher Scientific - San Diego, CA

Experience in the IVD medical device and/or biotechnology industry is preferred. The Scientist I will support within the Technical Operations Organization in...From Thermo... Read more ...