Biological
So-called junk DNA hides useful compounds
9 hours ago | Phys
Bio-Protection Research Centre scientists and collaborators have made a discovery that potentially opens the door to new medicines and biological pesticides.
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PsSubpathway: a software package for flexible identification of phenotype-specific subpathways in cancer progression
11 hours ago | Oxford Journals
AbstractSummarySubpathways, which are defined as local gene subregions within a biological pathway, have been reported to be associated with the occurrence and development of...
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Logomaker: beautiful sequence logos in Python
11 hours ago | Oxford Journals
AbstractSequence logos are visually compelling ways of illustrating the biological properties of DNA, RNA, and protein sequences, yet it is currently difficult to generate and...
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A new way to regulate gene expression
11 hours ago | Phys
Sometimes, unexpected research results are simply due to experimental error. Other times, it's the opposite-the scientists have uncovered a new phenomenon that reveals an even...
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Vertical and horizontal integration of multi-omics data with miodin
13 hours ago | Springer
Abstract
Background
Studies on multiple modalities of omics data such as transcriptomics, genomics and proteomics are growing in popularity, since they allow us to investigate...
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Robust Inductive Matrix Completion Strategy to Explore Associations Between LincRNAs and Human Disease Phenotypes
14 hours ago | IEEE/ACM
Over the past few years, it has been established that a number of long intergenic non-coding RNAs are linked to a wide variety of human diseases. The relationship among many...
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3gClust: Human Protein Cluster Analysis
14 hours ago | IEEE/ACM
We present a human protein cluster analysis by combining: 1) n-gram based amino acid frequency features, 2) optimal feature selection, 3) hierarchical clustering, and 4)...
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LncRNA MALAT1 Promotes Oxygen-Glucose Deprivation and Reoxygenation Induced Cardiomyocytes Injury Through Sponging miR-20b to Enhance beclin1-Mediated Autophagy
17 hours ago | Springer | 2 articles
Abstract
Background/Aims
LncRNA metastasis-associated lung adenocarcinoma transcript 1 is reported to be highly expressed in myocardial I/R injury and closely related to...
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Proteome changes of porcine follicular fluid during follicle development
1 day ago | Springer
Abstract
Background
Ovarian follicular fluid influences follicle and oocyte growth, but the fluctuation of its protein content during folliculogenesis has not been...
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Finding the smallest genes could yield outsized benefits
1 day ago | San Diego Biotechnology
LA JOLLA-While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But...
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World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
2nd International Conference on Tissue Science and Regenerative Medicine
This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...
Perceptive Unveils New $200M Fund to Invest in Early-Stage Biotechs
Perceptive Advisors, an investment firm with a long track record of life science investing across all points of development, is now stepping up to pump money into companies at... Read more ...
Merck Makes a Big Blood Cancer Bet With $2.7B Deal for ArQule
Merck is acquiring cancer drug developer ArQule for $2.7 billion , a cash deal that brings it a promising early-stage compound that could challenge a blockbuster leukemia drug... Read more ...
KalVista Pharma Eye Drug Partnered With Merck Flunks Phase 2 Test
A KalVista Pharmaceuticals eye drug at the center of a research collaboration with Merck has failed a mid-stage clinical trial. KalVista developed its drug, KVD001, to treat... Read more ...
Zentalis Steps Out With $147M Raised to Develop “Tried and True” Small Molecules
Zentalis Pharmaceuticals is banking on small molecules for cancer-leaving the “cool technologies” aside for a “tried and true” approach, says the CEO, who wants to let the... Read more ...
Scripps Research, AbbVie Expand Drug Discovery Deal Beyond Cancer
The Scripps Research Institute and AbbVie have agreed to broaden an existing drug discovery agreement focused on cancer cell therapies to now encompass treatments for other... Read more ...
Eying Cancer Combos, Sanofi to Splash Out $2.5B on San Diego's Synthorx
Synthorx is working to design new cytokine therapies for cancer using an “extended” genetic alphabet that could help avoid the shortcomings associated with earlier versions... Read more ...
Artificial Pancreas Keeps Patients Healthier: A Perspective
The late Mayo endocrinologists Russell Wilder, M.D., and Randall Sprague, M.D., would be smiling today at the news for patients with diabetes. Much of their lives and careers... Read more ...
Aurinia Plans FDA Filing After Lupus Nephritis Drug Hits Phase 3 Goals
Aurinia shares spiked last week after voclosporin, an immunosuppressant being tested in patients with lupus nephritis, met its primary and secondary endpoints in a Phase 3... Read more ...
AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets
After joining AstraZeneca's Boston Bio Hub incubator last year, Gatehouse Bio is now teaming up with the pharma company to identify potential drug targets in respiratory and... Read more ...
Business Development Manager, Europe - Invetech - San Diego, CA
Selling a combination of consulting services and technical product solutions in biotech, cell and gene therapy markets. Global VP Commercial .From Fortive - Tue, 10 Dec 2019... Read more ...