Biological

So-called junk DNA hides useful compounds

9 hours ago   |   Phys

Bio-Protection Research Centre scientists and collaborators have made a discovery that potentially opens the door to new medicines and biological pesticides.
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PsSubpathway: a software package for flexible identification of phenotype-specific subpathways in cancer progression

11 hours ago   |   Oxford Journals

AbstractSummarySubpathways, which are defined as local gene subregions within a biological pathway, have been reported to be associated with the occurrence and development of...
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Logomaker: beautiful sequence logos in Python

11 hours ago   |   Oxford Journals

AbstractSequence logos are visually compelling ways of illustrating the biological properties of DNA, RNA, and protein sequences, yet it is currently difficult to generate and...
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A new way to regulate gene expression

11 hours ago   |   Phys

Sometimes, unexpected research results are simply due to experimental error. Other times, it's the opposite-the scientists have uncovered a new phenomenon that reveals an even...
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Vertical and horizontal integration of multi-omics data with miodin

13 hours ago   |   Springer

Abstract Background Studies on multiple modalities of omics data such as transcriptomics, genomics and proteomics are growing in popularity, since they allow us to investigate...
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Robust Inductive Matrix Completion Strategy to Explore Associations Between LincRNAs and Human Disease Phenotypes

14 hours ago   |   IEEE/ACM

Over the past few years, it has been established that a number of long intergenic non-coding RNAs are linked to a wide variety of human diseases. The relationship among many...
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3gClust: Human Protein Cluster Analysis

14 hours ago   |   IEEE/ACM

We present a human protein cluster analysis by combining: 1) n-gram based amino acid frequency features, 2) optimal feature selection, 3) hierarchical clustering, and 4)...
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LncRNA MALAT1 Promotes Oxygen-Glucose Deprivation and Reoxygenation Induced Cardiomyocytes Injury Through Sponging miR-20b to Enhance beclin1-Mediated Autophagy

17 hours ago   |   Springer   |   2 articles

Abstract Background/Aims LncRNA metastasis-associated lung adenocarcinoma transcript 1 is reported to be highly expressed in myocardial I/R injury and closely related to...
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Proteome changes of porcine follicular fluid during follicle development

1 day ago   |   Springer

Abstract Background Ovarian follicular fluid influences follicle and oocyte growth, but the fluctuation of its protein content during folliculogenesis has not been...
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Finding the smallest genes could yield outsized benefits

1 day ago   |   San Diego Biotechnology

LA JOLLA-While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Perceptive Unveils New $200M Fund to Invest in Early-Stage Biotechs

Perceptive Unveils New $200M Fund to Invest in Early-Stage Biotechs

Perceptive Advisors, an investment firm with a long track record of life science investing across all points of development, is now stepping up to pump money into companies at... Read more ...

Merck Makes a Big Blood Cancer Bet With $2.7B Deal for ArQule

Merck Makes a Big Blood Cancer Bet With $2.7B Deal for ArQule

Merck is acquiring cancer drug developer ArQule for $2.7 billion , a cash deal that brings it a promising early-stage compound that could challenge a blockbuster leukemia drug... Read more ...

KalVista Pharma Eye Drug Partnered With Merck Flunks Phase 2 Test

KalVista Pharma Eye Drug Partnered With Merck Flunks Phase 2 Test

A KalVista Pharmaceuticals eye drug at the center of a research collaboration with Merck has failed a mid-stage clinical trial. KalVista developed its drug, KVD001, to treat... Read more ...

Zentalis Steps Out With $147M Raised to Develop “Tried and True” Small Molecules

Zentalis Steps Out With $147M Raised to Develop “Tried and True” Small Molecules

Zentalis Pharmaceuticals is banking on small molecules for cancer-leaving the “cool technologies” aside for a “tried and true” approach, says the CEO, who wants to let the... Read more ...

Scripps Research, AbbVie Expand Drug Discovery Deal Beyond Cancer

Scripps Research, AbbVie Expand Drug Discovery Deal Beyond Cancer

The Scripps Research Institute and AbbVie have agreed to broaden an existing drug discovery agreement focused on cancer cell therapies to now encompass treatments for other... Read more ...

Eying Cancer Combos, Sanofi to Splash Out $2.5B on San Diego's Synthorx

Eying Cancer Combos, Sanofi to Splash Out $2.5B on San Diego's Synthorx

Synthorx is working to design new cytokine therapies for cancer using an “extended” genetic alphabet that could help avoid the shortcomings associated with earlier versions... Read more ...

Artificial Pancreas Keeps Patients Healthier: A Perspective

Artificial Pancreas Keeps Patients Healthier: A Perspective

The late Mayo endocrinologists Russell Wilder, M.D., and Randall Sprague, M.D., would be smiling today at the news for patients with diabetes. Much of their lives and careers... Read more ...

Aurinia Plans FDA Filing After Lupus Nephritis Drug Hits Phase 3 Goals

Aurinia Plans FDA Filing After Lupus Nephritis Drug Hits Phase 3 Goals

Aurinia shares spiked last week after voclosporin, an immunosuppressant being tested in patients with lupus nephritis, met its primary and secondary endpoints in a Phase 3... Read more ...

AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets

AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets

After joining AstraZeneca's Boston Bio Hub incubator last year, Gatehouse Bio is now teaming up with the pharma company to identify potential drug targets in respiratory and... Read more ...

Business Development Manager, Europe - Invetech - San Diego, CA

Selling a combination of consulting services and technical product solutions in biotech, cell and gene therapy markets. Global VP Commercial .From Fortive - Tue, 10 Dec 2019... Read more ...