Cancer

A pathogenic variant in CHEK2 shows a founder effect in Portuguese Roma patients with thyroid cancer

4 days ago   |   Springer

Abstract Purpose Germline mutations in DNA repair-related genes have been recently reported in cases with familial non-medullary thyroid carcinoma. A Portuguese family from the...
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Curcumin loaded sub-30 nm targeting therapeutic lipid nanoparticles for synergistically blocking nasopharyngeal cancer growth and metastasis

6 days ago   |   Journal of Nanobiotechnology

Systemic chemotherapy is still the primary treatment for advanced-stage nasopharyngeal carcinoma , but only limited therapeutic success has been achieved in the past decade...
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Identification of unique subtype-specific interaction features in Class II zinc-dependent HDAC subtype binding pockets: A computational study

6 days ago   |   Journal of Biosciences

Abstract Zinc-dependent HDAC subtypes exhibit differential expression in various cancer types and significantly contribute to oncogenic cell transformation, and hence are...
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An engineered microfluidic blood‐brain barrier model to evaluate the anti‐metastatic activity of β‐boswellic acid

7 days ago   |   Wiley

Abstract Background The development of anti-cancer drugs with the ability to inhibit brain metastasis through the blood-brain barrier is substantially limited due to the lack...
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Amplification of oxidative stress with lycorine and gold-based nanocomposites for synergistic cascade cancer therapy

7 days ago   |   Journal of Nanobiotechnology

Despite advances of surgery and neoadjuvant chemotherapy during the past few decades, the therapeutic efficacy of current therapeutic protocol for osteosarcoma is still...
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Intratumoral administration of astatine-211-labeled gold nanoparticle for alpha therapy

7 days ago   |   Journal of Nanobiotechnology

211At is a high-energy α-ray emitter with a relatively short half-life and a high cytotoxicity for cancer cells. Its dispersion can be imaged using clinical scanners, and it...
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Discovery within human cell cycle process to bring new understanding of cellular diseases

7 days ago   |   ScienceDaily

New research has uncovered an essential mechanism coordinating the processes of cell division and adhesion within humans. This discovery has profound potential for advancing...
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Gilead-partnered Teneobio and its next-gen cancer work snapped up by Amgen for $2.5B

7 days ago   |   Fierce Biotech   |   2 articles

Gilead-partnered Teneobio and its next-gen cancer work snapped up by Amgen for $2.5B badams Wed, 07/28/2021 - 04:30
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GSK culls phase 2 RSV vaccine in kids, as feladilimab flops again in lung cancer

7 days ago   |   Fierce Biotech   |   2 articles

GSK culls phase 2 RSV vaccine in kids, as feladilimab flops again in lung cancer ntaylor Wed, 07/28/2021 - 08:54
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Ipsen pens early-stage, $14.5M programmed cell death cancer deal with BAKX Therapeutics

7 days ago   |   Fierce Biotech

Ipsen pens early-stage, $14.5M programmed cell death cancer deal with BAKX Therapeutics badams Wed, 07/28/2021 - 09:00
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

MicroRNA-17-5p Promotes Cardiac Hypertrophy by Targeting Mfn2 to Inhibit...

Abstract Pathological cardiac hypertrophy is the leading cause of heart failure, and miRNAs have been recognized as key factors in cardiac hypertrophy. This study aimed to... Read more ...

Scientist, Hematologic and Immunologic Toxicology - La Jolla, CA - Johnson &...

As part of the cutting-edge Global Predictive, Investigative and Translational Toxicology Team, the candidate will have the opportunity to work within...From Johnson & Johnson... Read more ...

Bringing Protection Back in Line

Bringing Protection Back in Line

Research refines platform to address immune disorders Dr. Esma Yolcu and Dr. Haval Shirwan, Co-pioneers of ProtEx technology By Davis Suppes | Bond LSC The things that protect... Read more ...

After 40 Years, HIV Presents Research Problems New and Old

After 40 Years, HIV Presents Research Problems New and Old

In the years since AIDS was first described in medical research, the scientific map of that disease has changed enormously. Once it was relatively empty. Now scientists... Read more ...

Exosomal circRNA HIPK3 knockdown inhibited cell proliferation and metastasis...

Abstract Prostate cancer is the second frequent malignancy among men in the world. Exosomal circular RNAs have been reported to function in PCa progression. The current study... Read more ...

Prognostic value and immunological characteristics of a novel...

Abstract Autophagy affects the development, progression, and prognosis of various cancers including pancreatic cancer. To develop an autophagy-related prognostic model of... Read more ...

Chiral nanomaterials for tumor therapy: autophagy, apoptosis, and...

Chirality is a fundamental characteristic of natural molecules and a crucial factor in the biochemical reactions of living cells and organisms. Recently, researchers have... Read more ...

Ramil the snow leopard tests positive for COVID at the San Diego Zoo

Zoo staff say the animal's symptoms are mild and are still investigating how he got infected Read more ...

Enhanced lignin biodegradation by consortium of white rot fungi: microbial...

As one of the major components of lignocellulosic biomass, lignin has been considered as the most abundant renewable aromatic feedstock in the world. Comparing with thermal or... Read more ...

Design and heterologous expression of a novel dimeric LL37 variant in Pichia...

The antimicrobial peptide LL37 is produced by white blood cells and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing... Read more ...