Cancer

Core-shell nanoparticles suppress metastasis and modify the tumour-supportive activity of cancer-associated fibroblasts

2 hours ago   |   Journal of Nanobiotechnology

Although accumulating evidence suggests that the crosstalk between malignant cells and cancer-associated fibroblasts actively contributes to tumour growth and metastatic...
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'Ancient' cellular discovery key to new cancer therapies

5 hours ago   |   ScienceDaily

Researchers have uncovered a metabolic system which could lead to new strategies for therapeutic cancer treatment. A team has found a link between a metabolic system in a...
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Carlsbad's Tyra Biosciences nets $50 million to combat drug resistance in cancer therapies

6 hours ago   |   San Diego Biotechnology

Early stage startup will hunt for drugs that can be deployed in precision oncology...
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Chi-Med stops pivotal pancreatic cancer trial upon early success

12 hours ago   |   Fierce Biotech

Hutchison China MediTech has stopped a phase 3 trial of surufatinib in pancreatic neuroendocrine tumors early for positive efficacy. An independent data monitoring committee...
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Trovagene to Present New Clinical Data for Onvansertib in Metastatic KRAS-Mutated Colorectal Cancer at ASCO 2020 Gastrointestinal Cancers Symposium

15 hours ago   |   San Diego Biotechnology   |   2 articles

SAN DIEGO, Jan. 21, 2020 /PRNewswire/ - Trovagene, Inc. , a clinical-stage, oncology therapeutics company developing onvansertib for the treatment of various cancers including...
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Calidi Biotherapeutics Secures Series A Investments to Advance Manufacturing

19 hours ago   |   San Diego Biotechnology

SAN DIEGO-- biotech-Calidi Biotherapeutics, Inc., a clinical?stage immuno-oncology company at the forefront of cell-based oncolytic virus immunotherapies for cancer, today...
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An overview of immunoinformatics approaches and databases linking T cell receptor repertoires to their antigen specificity

21 hours ago   |   Springer

Abstract Recent advances in molecular and bioinformatic methods have greatly improved our ability to study the formation of an adaptive immune response towards foreign...
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Establishing Suspension Cell Cultures for Improved Manufacturing of Oncolytic Adenovirus

1 day ago   |   Wiley

Recent clinical trials have shown the potential of oncolytic adenoviruses as a cancer immunotherapy. A successful transition of oncolytic adenovirus to clinical applications...
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Clinical Genomic Liaison - San Diego/West Coast - Decipher Biosciences - San Diego, CA

3 days ago   |   San Diego Biotechnology   |   2 articles

Experience in urology and/or cancer genomics is preferred, pharmaceutical or biotech industry experience also considered. Other duties may be assigned.From Decipher Biosciences...
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Hypoxia-induced changes in intragenic DNA methylation correlate with alternative splicing in breast cancer

3 days ago   |   Journal of Biosciences   |   2 articles

Abstract The tumor microenvironment is marked by gradients in the level of oxygen and nutrients, with oxygen levels reaching a minimum at the core of the tumor, a condition...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Of Science and Sea Urchins: Researchers Plumb Oceans for Biological Insights

Of Science and Sea Urchins: Researchers Plumb Oceans for Biological Insights

The ocean is home to more biodiversity than anywhere else on the planet-making it a largely untapped source of opportunity for researchers studying marine organisms as a source... Read more ...

Holistic process development to mitigate proteolysis of a subunit rotavirus...

Abstract To meet the challenges of global health, vaccine design and development must be reconsidered to achieve cost of goods as low as 15¢ per dose. A new recombinant... Read more ...

Core-shell nanoparticles suppress metastasis and modify the...

Although accumulating evidence suggests that the crosstalk between malignant cells and cancer-associated fibroblasts actively contributes to tumour growth and metastatic... Read more ...

Ternary nanocomposite carriers based on organic clay-lipid vesicles as an...

This study aimed to develop a new colon-targeted drug delivery system via the preparation of ternary nanocomposite carriers based on organic polymer, aminoclay and lipid... Read more ...

New image analysis method for time-lapse microscopy shows how giant viruses...

Viruses are probably the most peculiar "life forms" known to us, with each species having unique characteristics. One thing common to all viruses is that they attack a "host... Read more ...

Advancing the application of genomic sequences through 'Kmasker plants'

The development of next-generation-sequencing has enabled researchers to investigate genomes that might previously have been considered too complex or too expensive... Read more ...

Benchmarking principal component analysis for large-scale single-cell...

Principal component analysis is an essential method for analyzing single-cell RNA-seq datasets, but for large-scale scRNA-seq datasets, computation time is long and consumes... Read more ...

Internet Freedom Ten Years In

Hillary Clinton gave her first speech on internet freedom 10 years ago today... Read more ...

Sismonr: Simulation of In Silico Multi-Omic Networks with adjustable ploidy...

AbstractSummaryWe present sismonr, an R package for an integral generation and simulation of in silico biological systems. The package generates gene regulatory networks, which... Read more ...

METADOCK 2: A high-throughput parallel metaheuristic scheme for molecular...

AbstractMotivationMolecular docking methods are extensively used to predict the interaction between protein-ligand systems in terms of structure and binding affinity, through... Read more ...