Clinical

A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

1 day ago   |   Genome Biology   |   2 articles

Oncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a...
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Cancer immune control dynamics: a clinical data driven model of systemic immunity in patients with metastatic melanoma

1 day ago   |   BMC Bioinformatics

Recent clinical advances in cancer immuno-therapeutics underscore the need for improved understanding of the complex relationship between cancer and the multiple...
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Thiopeptides encoding biosynthetic gene clusters mined from bacterial genomes

1 day ago   |   Journal of Biosciences

Abstract Currently, we are at the threshold of the ‘post-antibiotic era' due to the global emergence of antimicrobial resistance , and hence there is a dire need to discover...
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Clinically applicable machine learning approaches to identify attributes of Chronic Kidney Disease for use in low-cost diagnostic screening

1 day ago   |   EMBS

Objective: Chronic kidney disease is a major public health concern worldwide. High costs of late-stage diagnosis and insufficient testing facilities can contribute to high...
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Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer

1 day ago   |   Genome Biology

Muscle-invasive bladder cancers are characterized by their distinct expression of luminal and basal genes, which could be used to predict key clinical features such as disease...
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Nanotechnology based solutions for anti-leishmanial impediments: a detailed insight

1 day ago   |   Journal of Nanobiotechnology

As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous...
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Antioxidant and C5a-blocking strategy for hepatic ischemia-reperfusion injury repair

1 day ago   |   Journal of Nanobiotechnology

Nonspecific liver uptake of nanomaterials after intravenous injection has hindered nanomedicine for clinical translation. However, nanomaterials' propensity for liver...
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Designing Multi-epitope Diagnosis of Gal d 5 and Gal d 6 Based on Immunoinformatics Approaches Against Egg Yolk Allergy

1 day ago   |   Springer   |   2 articles

Abstract Recent serological tests have shown that children who are allergic to egg white are also susceptible to egg yolk allergen components. Based on the clinical status and...
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Learning Multiparametric Biomarkers for Assessing MR-Guided Focused Ultrasound Treatments

2 days ago   |   EMBS

A significant challenge for noninvasive MR-guided focused ultrasound treatment is assessing the viability of treated tissue during and immediately after MRgFUS procedures...
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Senior Biostatistician - Biological Dynamics - San Diego, CA

2 days ago   |   San Diego Biotechnology   |   4 articles

The Senior Biostatistician provides statistical expertise and leadership to analytical and clinical development projects.From Biological Dynamics - Fri, 16 Apr 2021 05:39:53...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Power of light and oxygen clears Alzheimer's disease protein in live mice

A small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the brains of Alzheimer's disease... Read more ...

Inferring Metal Binding Sites in Flexible Regions of Proteins

ABSTRACT Metal ions are central to the molecular function of many proteins. Thus their knowledge in experimentally determined structure is important; however, such structures... Read more ...

Molecular basis for higher affinity of SARS‐CoV‐2 spike RBD for human ACE2...

Abstract Severe acute respiratory syndrome coronavirus‐2 has caused substantially more infections, deaths, and economic disruptions than the 2002‐2003 SARS‐CoV. The key to... Read more ...

The vaccine rollout is in full swing. What does that mean for COVID testing?

Public health experts say testing remains an important tool in tracking and controlling the spread of the pandemic Read more ...

Glycol chitosan-based tacrolimus-loaded nanomicelle therapy ameliorates...

Recently, we developed hydrophobically modified glycol chitosan nanomicelles loaded with tacrolimus for the targeted renal delivery of TAC. Herein, we determined whether the... Read more ...

Nanoparticle-mediated synergistic chemoimmunotherapy for tailoring cancer...

Nowadays, a potent challenge in cancer treatment is considered the lack of efficacious strategy, which has not been able to significantly reduce mortality. Chemoimmunotherapy... Read more ...

Alginate-chitosan core-shell microcapsule cultures of hepatic cells in a...

A small scale stirred bioreactor was designed and the effect of different agitation rates was investigated on HepG2 cells cultured in alginate-chitosan core-shell microcapsule... Read more ...

Aliphatic extractive effects on acetic acid catalysis of typical...

Xylo-oligosaccharide is the spotlight of functional sugar that improves the economic benefits of lignocellulose biorefinery. Acetic acid acidolysis technology provides a... Read more ...

Multi-omics analysis provides insights into lignocellulosic biomass...

Wood-decay basidiomycetes are effective for the degradation of highly lignified and recalcitrant plant substrates. The degradation of lignocellulosic materials by brown-rot... Read more ...

Lyophilized alginate-based microspheres containing Lactobacillus fermentum...

Lactobacillus fermentum D12 is an exopolysaccharide producing strain whose genome contains a putative eps operon. Whole-genome analysis of D12 was performed to disclose the... Read more ...