Gene Therapy

Designer cytokine makes paralyzed mice walk again

1 day ago   |   ScienceDaily

Using gene therapy, a research team has succeeded in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves.
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Rejuvenate Bio: Senior Scientist - Protein Engineering

2 days ago   |   San Diego Biotechnology

Competitive + moving, full health and Dental: Rejuvenate Bio: Using Rosetta to reengineer protein interactions to make cells do cool things using gene therapy San Diego, CA ...
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Senior Finance Manager - Cell and Gene Therapy - Thermo Fisher Scientific - Carlsbad, CA

2 days ago   |   San Diego Biotechnology

The candidate will be responsible for driving and managing key operating mechanisms in the global business such as forecasting and strategic planning, Data...From Thermo Fisher...
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Research Associate, In Vivo Gene Therapy - Poseida Therapeutics Inc - San Diego, CA

4 days ago   |   San Diego Biotechnology   |   14 articles

Poseida Therapeutics is seeking a talented and self-motivated research associate to join our Gene Therapy team. These may include but are not limited to:From Poseida...
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Research Scientist/Senior Research Scientist, Liver- targeted Gene Therapy - Poseida Therapeutics Inc - San Diego, CA

4 days ago   |   San Diego Biotechnology   |   14 articles

Poseida Therapeutics s seeking a talented and self-motivated scientist/senior scientist to join our Gene Therapy team. These may include but are not limited to:From Poseida...
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Research Scientist/Senior Research Scientist, Liver- targeted Gene Therapy - Poseida Therapeutics Inc - San Diego, CA

4 days ago   |   San Diego Biotechnology   |   14 articles

Ability to document, organize, communicate and present complex data sets to key stakeholders from diverse backgrounds. These may include but are not limited to:From Poseida...
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Quality Control Testing, Characterization and Critical Quality Attributes of Adeno‐Associated Virus Vectors Used for Human Gene Therapy

Quality Control Testing, Characterization and Critical Quality Attributes of Adeno‐Associated Virus Vectors Used for Human Gene Therapy

4 days ago   |   Wiley   |   6 articles

This article describes quality control testing and characterization of adeno‐associated virus gene therapy vectors for clinical product development. It explores the...
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Evaluation of the Single‐Use Fixed‐Bed Bioreactors in Scalable Virus Production

Evaluation of the Single‐Use Fixed‐Bed Bioreactors in Scalable Virus Production

4 days ago   |   Wiley   |   6 articles

Adherent cells can attach and grow in three‐dimensional fixed‐bed matrix. The single use disposable upstream technology has been implemented in many different viral vector and...
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Biomanufacturing of Gene Therapy Vectors

4 days ago   |   Wiley

Biotechnology Journal, Volume 16, Issue 1, January 2021.
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Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production

Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production

4 days ago   |   Wiley   |   6 articles

Modified Vaccinia Ankara virus is a viral vector used for gene therapies. Here, MVA virus is produced with AGE1.CR.pIX suspension cells using different platform technologies...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

PacBio and Invitae Team Up to Develop Ultra-High-Throughput Clinical Whole...

PacBio and Invitae Team Up to Develop Ultra-High-Throughput Clinical Whole Genome Sequencing Platform

The power of PacBio HiFi reads has enabled transformative research into human disease. A new collaboration with Invitae, a leader in medical genetics, is intended to help... Read more ...

STAT: Businesses across the vaccine supply chain must work together to make...

STAT: Businesses across the vaccine supply chain must work together to make Covid-19 vaccines

Andrey Zarur, CEO of GreenLight Biosciences, writes for STAT about the vaccine supply chain and how we need to work together to make Covid-19 vaccines. Credit: LEON NEAL/GETTY... Read more ...

IAmScience Leland Cseke

IAmScience Leland Cseke

By Becca Wolf | Bond LSC In a cluttered basement in Dearborn, Michigan, one could find Leland Cseke conducting amateur plant tissue culture experiments on his family's pool... Read more ...

Study: X-Rays Surrounding ‘Magnificent 7' May Be Traces of Sought-After Particle

Study: X-Rays Surrounding ‘Magnificent 7' May Be Traces of Sought-After Particle

An artistic rendering of the XMM-Newton space telescope. A study of archival data from the XMM-Newton and the Chandra X-ray space telescopes found evidence of high levels of... Read more ...

MendelVar: gene prioritisation at GWAS loci using phenotypic enrichment of...

AbstractMotivationGene prioritisation at human GWAS loci is challenging due to linkage disequilibrium and long-range gene regulatory mechanisms. However, identifying the causal... Read more ...

A two-step approach to testing overall effect of gene-environment...

AbstractMotivationWhile gene-environment interactions contribute importantly to many different phenotypes, detecting such interactions requires well-powered studies and has... Read more ...

A network-based deep learning methodology for stratification of tumor mutations

AbstractMotivationTumor stratification has a wide range of biomedical and clinical applications, including diagnosis, prognosis and personalized treatment. However, cancer is... Read more ...

Recognition of small molecule-RNA binding sites using RNA sequence and structure

AbstractMotivationRNA molecules become attractive small-molecule drug targets to treat disease in recent years. Computer-aided drug design can be facilitated by detecting the... Read more ...

ShinyÉPICo: a graphical pipeline to analyze Illumina DNA methylation arrays

AbstractSummaryIllumina DNA methylation bead arrays provide a cost-effective platform for the simultaneous analysis of a high number of human samples. However, the analysis can... Read more ...

PC2P: Parameter-free network-based prediction of protein complexes

AbstractMotivationPrediction of protein complexes from protein-protein interaction networks is an important problem in systems biology, as they control different cellular... Read more ...