10 minutes ago | Oxford Journals

AbstractMotivationSpatial transcriptomics technology is increasingly being applied because it enables the measurement of spatial gene expression in an intact tissue along with...
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Predicting effective drug combinations using gradient tree boosting based on features extracted from drug-protein heterogeneous network

40 minutes ago | Springer | 2 articles

Abstract Background Although targeted drugs have contributed to impressive advances in the treatment of cancer patients, their clinical benefits on tumor therapies are greatly...
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Genomic cut and paste using a class 1 CRISPR system

48 minutes ago | Phys

Almost from the moment DNA was discovered, the ability to fix or remove disease-causing genes in affected patients has been something of a holy grail of medicine. Now that this...
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Finding the smallest genes could yield outsized benefits

48 minutes ago | Phys

While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But these tiny...
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Identification of Hub Genes in Pediatric Medulloblastoma by Multiple-Microarray Analysis

1 hour ago | Springer

Abstract Pediatric medulloblastoma is the leading cause of cancer-related death in children. However, few studies have reported gene expression profiles of pediatric...
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AveXis Inc.: Senior Scientific Training Specialist - cGMP Gene Therapy

7 hours ago | San Diego Biotechnology

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego...
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Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study

8 hours ago | Springer

Abstract Pineoblastomas are rare, aggressive pediatric brain tumors of the pineal gland with modest overall survival despite intensive therapy. We sought to define the clinical...
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CRISPR System: A High-throughput Toolbox for Research and Treatment of Parkinson's Disease

8 hours ago | Springer

Abstract In recent years, the innovation of gene-editing tools such as the CRISPR/Cas9 system improves the translational gap of treatments mediated by gene therapy. The...
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Three transcriptional regulators positively regulate the biosynthesis of polycyclic tetramate macrolactams in Streptomyces xiamenensis 318

9 hours ago | Springer

Abstract Polycyclic tetramate macrolactams are a widely distributed class of structurally complex natural products, and most of them exhibit multiple biological activities...
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Faint gray bands in Drosophila melanogaster polytene chromosomes are formed by coding sequences of housekeeping genes

10 hours ago | Springer

Abstract In Drosophila melanogaster , the chromatin of interphase polytene chromosomes appears as alternating decondensed interbands and dense black or thin gray bands...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets

After joining AstraZeneca's Boston Bio Hub incubator last year, Gatehouse Bio is now teaming up with the pharma company to identify potential drug targets in respiratory and... Read more ...

IAmScience Mannie Liscum

For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...

Identification of Hub Genes in Pediatric Medulloblastoma by...

Abstract Pediatric medulloblastoma is the leading cause of cancer-related death in children. However, few studies have reported gene expression profiles of pediatric... Read more ...

MiR-338-5p ameliorates pathological cardiac hypertrophy by targeting CAMKIIδ

Abstract Pathological cardiac hypertrophy is characterized by an increase in cardiomyocyte size and thickening of the ventricular walls during the adaptive response to maintain... Read more ...

BioMed Realty Welcomes Amgen to Its Gateway of Pacific Campus

SAN DIEGO--BioMed Realty Welcomes Amgen to its Landmark Life Science Gateway of Pacific Campus in South San Francisco... Read more ...

FlowEMMi: an automated model-based clustering tool for microbial cytometric data

Abstract Background Flow cytometry is a powerful single-cell based measurement method to ascertain multidimensional optical properties of millions of cells. FCM is widely used... Read more ...

ASH: Amgen's BiTE stalls multiple myeloma relapse in mice in combo with BMS'...

Amgen is developing two bispecific T-cell engagers for multiple myeloma, one of which is designed with a longer half-life that could lessen the infusion time required for... Read more ...

ASH: Roche bispecific delivers for hard-to-treat lymphoma patients failed by...

Roche has rolled out new data showing mosunetuzumab can trigger complete responses in a tough group-lymphoma patients failed by CAR-Ts and other drugs. The phase 1/2b linked... Read more ...

AveXis Inc.: Senior Scientific Training Specialist - cGMP Gene Therapy

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...

Process Engineer I - Genentech - Oceanside, CA

Focus will be on one or more areas such as design, implementation and/or start-up of new and/or existing facilities with respect to process and/or clean utility...From... Read more ...