Genetics

CRISPR/Cas9‐mediated single and biallelic knockout of poplar STERILE APETALA leads to complete reproductive sterility

8 hours ago   |   Wiley

Abstract The spread of highly domesticated, exotic, or genetically‐modified organisms into wild and feral populations and/or their genes beyond the boundaries of plantations...
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Engineering the Gut Microbiome for Treatment of Obesity: A Review of Current Understanding and Progress

11 hours ago   |   Wiley

Abstract Background Obesity is a complex, multifactorial disease that is increasing in prevalence despite extensive research and efforts to curb it. Over the last decade, gut...
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Avian speciation: Uniform vs. particolored plumage

15 hours ago   |   ScienceDaily

Although carrion crows and hooded crows are almost indistinguishable genetically, they avoid mating with each other. Researchers have now identified a mutation that appears to...
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Cell type-specific genome scans of DNA methylation divergence indicate an important role for transposable elements

1 day ago   |   Genome Biology

In population genomics, genetic diversity measures play an important role in genome scans for divergent sites. In population epigenomics, comparable tools are rare although the...
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Genetic differences between global American Crocodile populations identified in DNA analysis

1 day ago   |   ScienceDaily

A genetic analysis of the American crocodile has re-established our understanding of its population structure, aiding its conservation.
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High‐resolution temporal dynamic transcriptome landscape reveals a GhCAL‐mediated flowering regulatory pathway in cotton

2 days ago   |   Wiley

Summary The transition from vegetative to reproductive growth is very important for early maturity in cotton. However, the genetic control of this highly dynamic and complex...
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Genomic analyses reveal the genetic basis of early maturity and identification of loci and candidate genes in upland cotton

2 days ago   |   Wiley

Summary Although upland cotton originated in the tropics, this early maturity cotton can be planted as far north as 46°N in China due to the accumulation of numerous phenotypic...
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Predicting mechanism of action of cellular perturbations with pathway activity signatures

3 days ago   |   Oxford Journals

AbstractMotivationMisregulation of signaling pathway activity is etiologic for many human diseases, and modulating activity of signaling pathways is often the preferred...
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Associate Director - Genetic Epidemiology - Retrophin - San Diego, CA

4 days ago   |   San Diego Biotechnology   |   4 articles

Excellent collaboration skills with strong attention to detail and the ability to multi-task and manage complexity. Experience in rare diseases is a plus. $80,000 a yearFrom...
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RNA key in helping stem cells know what to become

5 days ago   |   ScienceDaily

If every cell has the same genetic blueprint, why does an eye cell look and act so differently than a brain cell or skin cell? In a new study, researchers come one step closer...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

The drug that Equillium licensed from India-based pharma giant Biocon has received authorization for emergency use in that country in patients hospitalized with COVID-19. The... Read more ...

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

A Blueprint Medicines cancer drug candidate currently under FDA review will have the marketing muscle of Roche behind it if it wins regulatory approval. The two companies are... Read more ...

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Have you had your say yet? The 2020 National Xconomy Awards represent the very best our life science industry has to offer. It is our privilege to recognize emerging companies... Read more ...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on Digital Health

Miss Xconomy's Xcelerating Life Sciences Boston: Biopharma's Future in Digital Health event or want to revisit the insightful content? Our new podcast and special report... Read more ...

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

At the year's start Thousand Oaks, CA-based Amgen closed a strategic collaboration with BeiGene, investing $2.8 billion to gain a presence in what's becoming an ever-more... Read more ...

Scientists Successfully Demonstrate a New Experiment in the Search for...

Scientists Successfully Demonstrate a New Experiment in the Search for Theorized ‘Neutrinoless' Process

The CUPID-Mo detector is installed in the Edelweiss cryostat at Modane Underground Laboratory in France. Nuclear physicists affiliated with the U.S. Department of Energy's... Read more ...

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

Three biotech companies collectively raised $584 million in their initial public offerings last week, continuing a streak of IPOs that has the healthcare sector playing a... Read more ...

Expression, homology modeling and enzymatic characterization of a new...

Β-mannanase can hydrolyze β-1,4 glycosidic bond of mannan by the manner of endoglycosidase to generate mannan-oligosaccharides. Currently, β-mannanase has been widely applied... Read more ...

De novo resveratrol production through modular engineering of an Escherichia...

Resveratrol is a plant secondary metabolite with diverse, potential health-promoting benefits. Due to its nutraceutical merit, bioproduction of resveratrol via microbial... Read more ...

From monomer to fibril: Abeta‐amyloid binding to Aducanumab antibody studied...

Abstract Alzheimer's disease is one of the most common causes of dementia. It is believed that the aggregation of short Aβ‐peptides to form oligomeric and protofibrillar... Read more ...