Genetics
To save koalas from fire, we need to start putting their genetic material on ice
8 hours ago | Phys
Thousands of koalas may have died in fires burning through New South Wales but expert evidence to a state parliamentary inquiry on Monday said we are unlikely to ever know the...
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Longitudinal linear combination test for gene set analysis
12 hours ago | Springer | 2 articles
Abstract
Background
Although microarray studies have greatly contributed to recent genetic advances, lack of replication has been a continuing concern in this area. Complex...
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Human genetics and genomics research in Ecuador: historical survey, current state, and future directions
12 hours ago | Springer
Abstract
Background
In South America, the history of human genetics is extensive and its beginnings go back to the onset of the twentieth century. In Ecuador, the historical...
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Eying Cancer Combos, Sanofi to Splash Out $2.5B on San Diego's Synthorx
19 hours ago | Xconomy
Synthorx is working to design new cytokine therapies for cancer using an “extended” genetic alphabet that could help avoid the shortcomings associated with earlier versions...
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Finding the smallest genes could yield outsized benefits
1 day ago | San Diego Biotechnology
LA JOLLA-While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But...
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Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?
1 day ago | Springer
Abstract
Background
The canine hookworm, Ancylostoma caninum is the most prevalent and important intestinal nematode parasite of dogs in the USA. Hookworms are typically well...
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Finding the smallest genes could yield outsized benefits
1 day ago | Phys
While scientists know of about 25,000 genes that code for biologically important proteins, additional, smaller genes hiding in our DNA may be just as important. But these tiny...
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CRISPR System: A High-throughput Toolbox for Research and Treatment of Parkinson's Disease
1 day ago | Springer
Abstract
In recent years, the innovation of gene-editing tools such as the CRISPR/Cas9 system improves the translational gap of treatments mediated by gene therapy. The...
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SPG8 mutations in Italian families: clinical data and literature review
1 day ago | Springer
Abstract
Background
Spastic paraplegia type 8 is an autosomal-dominant form of hereditary spastic paraplegia caused by a mutation in the KIAA0196 gene. SPG8 accounts for 1% of...
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Understanding sheath blight resistance in rice: the road behind and the road ahead
2 days ago | Wiley
Abstract
Rice Sheath blight disease, caused by the basidiomycetous necrotrophy Rhizoctonia solani, became one of the major threats to the rice cultivation worldwide, especially...
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World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
2nd International Conference on Tissue Science and Regenerative Medicine
This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...
Perceptive Unveils New $200M Fund to Invest in Early-Stage Biotechs
Perceptive Advisors, an investment firm with a long track record of life science investing across all points of development, is now stepping up to pump money into companies at... Read more ...
Merck Makes a Big Blood Cancer Bet With $2.7B Deal for ArQule
Merck is acquiring cancer drug developer ArQule for $2.7 billion , a cash deal that brings it a promising early-stage compound that could challenge a blockbuster leukemia drug... Read more ...
KalVista Pharma Eye Drug Partnered With Merck Flunks Phase 2 Test
A KalVista Pharmaceuticals eye drug at the center of a research collaboration with Merck has failed a mid-stage clinical trial. KalVista developed its drug, KVD001, to treat... Read more ...
Zentalis Steps Out With $147M Raised to Develop “Tried and True” Small Molecules
Zentalis Pharmaceuticals is banking on small molecules for cancer-leaving the “cool technologies” aside for a “tried and true” approach, says the CEO, who wants to let the... Read more ...
Scripps Research, AbbVie Expand Drug Discovery Deal Beyond Cancer
The Scripps Research Institute and AbbVie have agreed to broaden an existing drug discovery agreement focused on cancer cell therapies to now encompass treatments for other... Read more ...
Eying Cancer Combos, Sanofi to Splash Out $2.5B on San Diego's Synthorx
Synthorx is working to design new cytokine therapies for cancer using an “extended” genetic alphabet that could help avoid the shortcomings associated with earlier versions... Read more ...
Artificial Pancreas Keeps Patients Healthier: A Perspective
The late Mayo endocrinologists Russell Wilder, M.D., and Randall Sprague, M.D., would be smiling today at the news for patients with diabetes. Much of their lives and careers... Read more ...
Aurinia Plans FDA Filing After Lupus Nephritis Drug Hits Phase 3 Goals
Aurinia shares spiked last week after voclosporin, an immunosuppressant being tested in patients with lupus nephritis, met its primary and secondary endpoints in a Phase 3... Read more ...
AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets
After joining AstraZeneca's Boston Bio Hub incubator last year, Gatehouse Bio is now teaming up with the pharma company to identify potential drug targets in respiratory and... Read more ...
Alzheimer's drug candidates reverse broader aging, study shows
LA JOLLA-In mouse models of Alzheimer's disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, Salk... Read more ...