Genome

Co-opted transposons help perpetuate conserved higher-order chromosomal structures

2 hours ago   |   Genome Biology

Transposable elements make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include binding sites for...
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ScMAGeCK links genotypes with multiple phenotypes in single-cell CRISPR screens

2 hours ago   |   Genome Biology   |   2 articles

We present scMAGeCK, a computational framework to identify genomic elements associated with multiple expression-based phenotypes in CRISPR/Cas9 functional screening that uses...
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Unravelling arthropod genomic diversity over 500 million years of evolution

4 hours ago   |   ScienceDaily

The evolutionary innovations of insects and other arthropods are as numerous as they are wondrous, from terrifying fangs and stingers to exquisitely colored wings and ingenious...
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CircMeta: a unified computational framework for genomic feature annotation and differential expression analysis of circular RNAs

6 hours ago   |   Oxford Journals   |   2 articles

AbstractMotivationCircular RNAs , a class of non-coding RNAs generated from non-canonical back-splicing events, have emerged to play key roles in many biological processes...
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Gwasrapidd: an R package to query, download and wrangle GWAS catalog data

6 hours ago   |   Oxford Journals

AbstractMotivationThe National Human Genome Research Institute Catalog of Published Genome-Wide Association Studies Catalog has collected, curated and made available data from...
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Predicting the effects of SNPs on transcription factor binding affinity

6 hours ago   |   Oxford Journals

AbstractMotivationGenome-wide association studies have revealed that 88% of disease-associated single-nucleotide polymorphisms reside in noncoding regions. However, noncoding...
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DNA Rchitect: an R based visualizer for network analysis of chromatin interaction data

6 hours ago   |   Oxford Journals

AbstractMotivationVisualization of multiple genomic data generally requires the use of public or commercially hosted browsers. Flexible visualization of chromatin interaction...
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ArtiFuse-computational validation of fusion gene detection tools without relying on simulated reads

6 hours ago   |   Oxford Journals

AbstractMotivationGene fusions are an important class of transcriptional variants that can influence cancer development and can be predicted from RNA sequencing data by...
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MOOMIN - Mathematical explOration of 'Omics data on a MetabolIc Network

6 hours ago   |   Oxford Journals

AbstractMotivationAnalysis of differential expression of genes is often performed to understand how the metabolic activity of an organism is impacted by a perturbation...
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'Jumping genes' help stabilize DNA folding patterns

22 hours ago   |   Phys   |   2 articles

"Jumping genes"-bits of DNA that can move from one spot in the genome to another-are well-known for increasing genetic diversity over the long course of evolution. Now, new...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Kaitlyn Waters

IAmScience Kaitlyn Waters

By Mariah Cox | Bond LSC It's common knowledge that all Ph.D. candidates must complete research in preparation for a dissertation, but what happens when one's faculty mentor... Read more ...

Alumni Spotlight: Barry A. Johnson

Alumni Spotlight: Barry A. Johnson

Barry Johnson with his son and daughter. Barry Johnson '87 had a great experience at the university while working on his Bachelor's degree in Agricultural Engineering. Johnson... Read more ...

Bio Roundup: Coronavirus Concerns, Sarepta's CRL, Eye Drug OK'd & More

Bio Roundup: Coronavirus Concerns, Sarepta's CRL, Eye Drug OK'd & More

Company news slowed somewhat this week, perhaps as some took the federal Martin Luther King Jr. Day holiday away from the office and others recovered from back-to-back meetings... Read more ...

Q&A With Eric Seaborg: Science Writer, Author, and Outdoorsman

Q&A With Eric Seaborg: Science Writer, Author, and Outdoorsman

Eric Seaborg Eric Seaborg, a writer and author, outdoorsman and environmentalist, has a love for hiking that he shared with his father, the late chemist and Nobel laureate... Read more ...

Project to Rapidly Sequence Maize Pangenome Delivers Publicly Available Resource

Project to Rapidly Sequence Maize Pangenome Delivers Publicly Available Resource

Matt Hufford, associate professor at Iowa State University, helped produce a 26-line maize pangenome assembly collection Maize researchers have been rejoicing over a New Year's... Read more ...

Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

Epizyme won accelerated FDA approval Thursday for a drug developed to treat the rare cancer epithelioid sarcoma. The regulatory decision for the Epizyme drug, tazemetostat... Read more ...

CUBIC: an atlas of genetic architecture promises directed maize improvement

Identifying genotype-phenotype links and causative genes from quantitative trait loci is challenging for complex agronomically important traits. To accelerate maize gene... Read more ...

Co-opted transposons help perpetuate conserved higher-order chromosomal...

Transposable elements make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include binding sites for... Read more ...

Why eating yogurt may help lessen the risk of breast cancer

One of the causes of breast cancer may be inflammation triggered by harmful bacteria suggest researchers. Scientists advise consuming natural yogurt, which contains beneficial... Read more ...

Why cells need acidic lysosomes

Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to... Read more ...