Metabolic engineering

Improving cellulases production by Myceliophthora thermophila through disruption of protease genes

6 days ago   |   Springer

Abstract Objective To identify main protease genes for the proteolytic degradation of cellulases in M. thermophila and generate a lower-proteases fungal host that can be used...
Read more ...

Optimization of protein isolation by proteomic qualification from Cutaneotrichosporon oleaginosus

6 days ago   |   Springer

Abstract In the last decades, microbial oils have been extensively investigated as a renewable platform for biofuel and oleochemical production. Offering a potent alternative...
Read more ...

Multiplex CRISPR/Cas9‐mediated metabolic engineering increases soybean isoflavone content and resistance to soybean mosaic virus

13 days ago   |   Wiley

Abstract Isoflavonoids, which include a variety of secondary metabolites, are derived from the phenylpropanoid pathway and are distributed predominantly in leguminous plants...
Read more ...

Efficient Cas9-based genome editing of Rhodobacter sphaeroides for metabolic engineering

14 days ago   |   Microbial Cell Factories

Rhodobacter sphaeroides is a metabolically versatile bacterium that serves as a model for analysis of photosynthesis, hydrogen production and terpene biosynthesis. The...
Read more ...

High production of valencene in Saccharomyces cerevisiae through metabolic engineering

1 month ago   |   Microbial Cell Factories   |   2 articles

The biological synthesis of high value compounds in industry through metabolically engineered microorganism factories has received increasing attention in recent years...
Read more ...

Metabolic engineering Escherichia coli for efficient production of icariside D2

1 month ago   |   Biotechnology for Biofuels

Icariside D2 is a plant-derived natural glycoside with pharmacological activities of inhibiting angiotensin-converting enzyme and killing leukemia cancer cells. Production of...
Read more ...

Comprehensive analysis of metabolic sensitivity of 1,4‐butanediol producing Escherichia coli toward substrate and oxygen availability

1 month ago   |   Wiley

Abstract Nowadays, chemical production of 1,4‐butanediol is supplemented by biotechnological processes using a genetically modified Escherichia coli strain, which is an...
Read more ...

Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose

1 month ago   |   Microbial Cell Factories

Aromatic amino acids and their derivatives are valuable chemicals and are precursors for different industrially compounds. p-Coumaric acid is the main building block for...
Read more ...

Comprehensive analysis of metabolic sensitivity of 1,4‐butanediol producing E. coli towards substrate and oxygen availability

1 month ago   |   Wiley   |   2 articles

Abstract Nowadays, chemical production of 1,4‐butanediol is supplemented by biotechnological processes using a genetically modified E. coli strain, which is an industrial...
Read more ...

Metabolic engineering with ATP-citrate lyase and nitrogen source supplementation improves itaconic acid production in Aspergillus niger

2 monthes ago   |   Biotechnology for Biofuels

Bio-based production of organic acids promises to be an attractive alternative for the chemicals industry to substitute petrochemicals as building-block chemicals. In recent...
Read more ...


Register you to post on BioTech Mag

Free Registration

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Perceptive Unveils New $200M Fund to Invest in Early-Stage Biotechs

Perceptive Unveils New $200M Fund to Invest in Early-Stage Biotechs

Perceptive Advisors, an investment firm with a long track record of life science investing across all points of development, is now stepping up to pump money into companies at... Read more ...

Merck Makes a Big Blood Cancer Bet With $2.7B Deal for ArQule

Merck Makes a Big Blood Cancer Bet With $2.7B Deal for ArQule

Merck is acquiring cancer drug developer ArQule for $2.7 billion , a cash deal that brings it a promising early-stage compound that could challenge a blockbuster leukemia drug... Read more ...

KalVista Pharma Eye Drug Partnered With Merck Flunks Phase 2 Test

KalVista Pharma Eye Drug Partnered With Merck Flunks Phase 2 Test

A KalVista Pharmaceuticals eye drug at the center of a research collaboration with Merck has failed a mid-stage clinical trial. KalVista developed its drug, KVD001, to treat... Read more ...

Zentalis Steps Out With $147M Raised to Develop “Tried and True” Small Molecules

Zentalis Steps Out With $147M Raised to Develop “Tried and True” Small Molecules

Zentalis Pharmaceuticals is banking on small molecules for cancer-leaving the “cool technologies” aside for a “tried and true” approach, says the CEO, who wants to let the... Read more ...

Scripps Research, AbbVie Expand Drug Discovery Deal Beyond Cancer

Scripps Research, AbbVie Expand Drug Discovery Deal Beyond Cancer

The Scripps Research Institute and AbbVie have agreed to broaden an existing drug discovery agreement focused on cancer cell therapies to now encompass treatments for other... Read more ...

Eying Cancer Combos, Sanofi to Splash Out $2.5B on San Diego's Synthorx

Eying Cancer Combos, Sanofi to Splash Out $2.5B on San Diego's Synthorx

Synthorx is working to design new cytokine therapies for cancer using an “extended” genetic alphabet that could help avoid the shortcomings associated with earlier versions... Read more ...

Artificial Pancreas Keeps Patients Healthier: A Perspective

Artificial Pancreas Keeps Patients Healthier: A Perspective

The late Mayo endocrinologists Russell Wilder, M.D., and Randall Sprague, M.D., would be smiling today at the news for patients with diabetes. Much of their lives and careers... Read more ...

Aurinia Plans FDA Filing After Lupus Nephritis Drug Hits Phase 3 Goals

Aurinia Plans FDA Filing After Lupus Nephritis Drug Hits Phase 3 Goals

Aurinia shares spiked last week after voclosporin, an immunosuppressant being tested in patients with lupus nephritis, met its primary and secondary endpoints in a Phase 3... Read more ...

AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets

AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets

After joining AstraZeneca's Boston Bio Hub incubator last year, Gatehouse Bio is now teaming up with the pharma company to identify potential drug targets in respiratory and... Read more ...

Business Development Manager, Europe - Invetech - San Diego, CA

Selling a combination of consulting services and technical product solutions in biotech, cell and gene therapy markets. Global VP Commercial .From Fortive - Tue, 10 Dec 2019... Read more ...