Nature

Engineered hydrogels for brain tumor culture and therapy

15 hours ago   |   Springer

Abstract Brain tumors' severity ranges from benign to highly aggressive and invasive. Bioengineering tools can assist in understanding the pathophysiology of these tumors from...
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Fabrication of paper-based devices for in vitro tissue modeling

15 hours ago   |   Springer

Abstract Paper devices have recently attracted considerable attention as a class of cost-effective cell culture substrates for various biomedical applications. The paper...
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TE-greedy-nester: structure-based detection of LTR retrotransposons and their nesting

18 hours ago   |   Oxford Journals

AbstractMotivationTransposable elements in eukaryotes often get inserted into one another, forming sequences that become a complex mixture of full-length elements and their...
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In vivo creation of plasmid pCRT01 and its use for the construction of carotenoid-producing Paracoccus spp. strains that grow efficiently on industrial wastes

1 day ago   |   Microbial Cell Factories

Carotenoids are natural tetraterpene pigments widely utilized in the food, pharmaceutical and cosmetic industries. Currently, chemical synthesis of these compounds outperforms...
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Immunomodulatory properties of bone marrow mesenchymal stem cells

1 day ago   |   Journal of Biosciences

Abstract Bone marrow mesenchymal stem cells are multipotent progenitor cells of mesodermal origin possessing multilineage differentiation potential and ease of expansion in...
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Sanofi Pays Kymera $150M to Kick Off Protein Degrader Partnership

Sanofi Pays Kymera $150M to Kick Off Protein Degrader Partnership

5 days ago   |   Xconomy

Kymera Therapeutics has signed a deal with French biopharma Sanofi to advance two potential treatments for immune-inflammatory diseases that leverage the Cambridge, MA-based...
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Gastruloids Stand In for Early Human Embryos

5 days ago   |   DNA Science

Remember human embryonic stem cells? We don't hear much about them anymore. And so I was surprised to see an application of the controversial cells to grow human embryo-like...
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Preventing breast cancer metastasis by reactivating natural killer immune cells

5 days ago   |   Fierce Biotech

Preventing breast cancer metastasis by reactivating natural killer immune cells aliu Thu, 07/09/2020 - 05:25
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The bottromycin epimerase BotH defines a group of atypical α/β-hydrolase-fold enzymes

6 days ago   |   ACS Division of Biological Chemistry

Nature Chemical Biology, Published online: 29 June 2020; doi:10.1038/s41589-020-0569-y BotH is an unusual α/β-hydrolase-fold enzyme that catalyzes epimerization of an aspartate...
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Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel

6 days ago   |   ACS Division of Biological Chemistry   |   4 articles

Nature Chemical Biology, Published online: 29 June 2020; doi:10.1038/s41589-020-0578-x Structural and biochemical analysis reveal that tetracenomycin X acts as an inhibitor of...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

The drug that Equillium licensed from India-based pharma giant Biocon has received authorization for emergency use in that country in patients hospitalized with COVID-19. The... Read more ...

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

A Blueprint Medicines cancer drug candidate currently under FDA review will have the marketing muscle of Roche behind it if it wins regulatory approval. The two companies are... Read more ...

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Have you had your say yet? The 2020 National Xconomy Awards represent the very best our life science industry has to offer. It is our privilege to recognize emerging companies... Read more ...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on Digital Health

Miss Xconomy's Xcelerating Life Sciences Boston: Biopharma's Future in Digital Health event or want to revisit the insightful content? Our new podcast and special report... Read more ...

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

At the year's start Thousand Oaks, CA-based Amgen closed a strategic collaboration with BeiGene, investing $2.8 billion to gain a presence in what's becoming an ever-more... Read more ...

Scientists Successfully Demonstrate a New Experiment in the Search for...

Scientists Successfully Demonstrate a New Experiment in the Search for Theorized ‘Neutrinoless' Process

The CUPID-Mo detector is installed in the Edelweiss cryostat at Modane Underground Laboratory in France. Nuclear physicists affiliated with the U.S. Department of Energy's... Read more ...

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

Three biotech companies collectively raised $584 million in their initial public offerings last week, continuing a streak of IPOs that has the healthcare sector playing a... Read more ...

Inverse Liquid Solid Chromatography to Evaluate Drug Interactions with...

Abstract Body‐on‐a‐chip and organ‐on‐a‐chip systems utilize polydimethylsiloxane because of the relative suitability of the material for fabrication of microfluidic channels... Read more ...

Expression, homology modeling and enzymatic characterization of a new...

Β-mannanase can hydrolyze β-1,4 glycosidic bond of mannan by the manner of endoglycosidase to generate mannan-oligosaccharides. Currently, β-mannanase has been widely applied... Read more ...

De novo resveratrol production through modular engineering of an Escherichia...

Resveratrol is a plant secondary metabolite with diverse, potential health-promoting benefits. Due to its nutraceutical merit, bioproduction of resveratrol via microbial... Read more ...