RNA

RNA key in helping stem cells know what to become

5 days ago   |   ScienceDaily

If every cell has the same genetic blueprint, why does an eye cell look and act so differently than a brain cell or skin cell? In a new study, researchers come one step closer...
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Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data

6 days ago   |   Genome Biology

High-throughput single-cell RNA-seq is a powerful tool for studying gene expression in single cells. Most current scRNA-seq bioinformatics tools focus on analysing overall...
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Executive Assistant - Arcturus Therapeutics - San Diego, CA

7 days ago   |   San Diego Biotechnology   |   6 articles

A high level of organizational skills and attention to detail is required. Our team has extensive experience in the discovery and development of RNA medicines,...From Indeed...
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Quantile normalization of single-cell RNA-seq read counts without unique molecular identifiers

10 days ago   |   Genome Biology   |   2 articles

Single-cell RNA-seq profiles gene expression of individual cells. Unique molecular identifiers remove duplicates in read counts resulting from polymerase chain reaction, a...
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Whole Genome Sequence of Xylella fastidiosa ATCC 35879 T and Detection of Genome Rearrangements Within Subsp. fastidiosa

11 days ago   |   Springer

Abstract Xylella fastidiosa is a Gram-negative and nutritionally fastidious bacterial pathogen causing Pierce's disease of grapevine and other plant diseases. X. fastidiosa...
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PRIME: a probabilistic imputation method to reduce dropout effects in single-cell RNA sequencing

11 days ago   |   Oxford Journals

AbstractSummarySingle-cell RNA sequencing technology provides a novel means to analyze the transcriptomic profiles of individual cells. The technique is vulnerable, however, to...
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Bayesian structural equation modeling in multiple omics data with application to circadian genes

11 days ago   |   Oxford Journals   |   2 articles

AbstractMotivationIt is well known that the integration among different data-sources is reliable because of its potential of unveiling new functionalities of the genomic...
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Using AnABlast for intergenic sORF prediction in the C. elegans genome

12 days ago   |   Oxford Journals

AbstractMotivationShort bioactive peptides encoded by small open reading frames play important roles in eukaryotes. Bioinformatics prediction of ORFs is an early step in a...
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Simulation, Power Evaluation, and Sample Size Recommendation for Single Cell RNA-seq

12 days ago   |   Oxford Journals

AbstractMotivationDetermining the sample size for adequate power to detect statistical significance is a crucial step at the design stage for high-throughput experiments. Even...
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GPress: a framework for querying General Feature Format files and expression files in a compressed form

13 days ago   |   Oxford Journals

AbstractMotivationSequencing data are often summarized at different annotation levels for further analysis, generally using the general feature format or its descendants, gene...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

The drug that Equillium licensed from India-based pharma giant Biocon has received authorization for emergency use in that country in patients hospitalized with COVID-19. The... Read more ...

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

A Blueprint Medicines cancer drug candidate currently under FDA review will have the marketing muscle of Roche behind it if it wins regulatory approval. The two companies are... Read more ...

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Have you had your say yet? The 2020 National Xconomy Awards represent the very best our life science industry has to offer. It is our privilege to recognize emerging companies... Read more ...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on Digital Health

Miss Xconomy's Xcelerating Life Sciences Boston: Biopharma's Future in Digital Health event or want to revisit the insightful content? Our new podcast and special report... Read more ...

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

At the year's start Thousand Oaks, CA-based Amgen closed a strategic collaboration with BeiGene, investing $2.8 billion to gain a presence in what's becoming an ever-more... Read more ...

Scientists Successfully Demonstrate a New Experiment in the Search for...

Scientists Successfully Demonstrate a New Experiment in the Search for Theorized ‘Neutrinoless' Process

The CUPID-Mo detector is installed in the Edelweiss cryostat at Modane Underground Laboratory in France. Nuclear physicists affiliated with the U.S. Department of Energy's... Read more ...

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

Three biotech companies collectively raised $584 million in their initial public offerings last week, continuing a streak of IPOs that has the healthcare sector playing a... Read more ...

Inverse Liquid Solid Chromatography to Evaluate Drug Interactions with...

Abstract Body‐on‐a‐chip and organ‐on‐a‐chip systems utilize polydimethylsiloxane because of the relative suitability of the material for fabrication of microfluidic channels... Read more ...

Expression, homology modeling and enzymatic characterization of a new...

Β-mannanase can hydrolyze β-1,4 glycosidic bond of mannan by the manner of endoglycosidase to generate mannan-oligosaccharides. Currently, β-mannanase has been widely applied... Read more ...

De novo resveratrol production through modular engineering of an Escherichia...

Resveratrol is a plant secondary metabolite with diverse, potential health-promoting benefits. Due to its nutraceutical merit, bioproduction of resveratrol via microbial... Read more ...