Repeat expansion disorder

INDIGO Expands Discovery Platform to Include Zebrafish Assays

1 day ago   |   Indigo Biosciences

Expansion Meets Industry Demand for Pre-Clinical Models for Cancer and Environmental Research State College, PA - INDIGO Biosciences, the recognized industry leader in nuclear...
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TET methylcytosine oxidases: new insights from a decade of research

3 days ago   |   Journal of Biosciences

Abstract In mammals, DNA methyltransferases transfer a methyl group from S-adenosylmethionine to the 5 position of cytosine in DNA. The product of this reaction...
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Emendo Eyes the Clinic for CRISPR Therapy That Makes Single-Gene Edits

Emendo Eyes the Clinic for CRISPR Therapy That Makes Single-Gene Edits

3 days ago   |   Xconomy

CRISPR gene editing offers the potential to selectively edit the genetic mutations causing inherited diseases, but Emendo Biotherapeutics CEO David Baram contends it's not...
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Differential network analysis of multiple human tissue interactomes highlights tissue-selective processes and genetic disorder genes

4 days ago   |   Oxford Journals

AbstractMotivationDifferential network analysis, designed to highlight network changes between conditions, is an important paradigm in network biology. However, differential...
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The Immune Epitope Database and Analysis Resource Program 2003-2018: reflections and outlook

4 days ago   |   Springer   |   2 articles

Abstract The Immune Epitope Database and Analysis Resource contains information related to antibodies and T cells across an expansive scope of research fields (infectious...
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Fabrication and characterization of PLGA nanoparticles encapsulating large CRISPR-Cas9 plasmid

4 days ago   |   Journal of Nanobiotechnology

The clustered regularly interspaced short palindromic repeats and Cas9 protein system is a revolutionary tool for gene therapy. Despite promising reports of the utility of...
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Researchers solve protein structures to fight asthma

5 days ago   |   Phys

Biophysicists from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases have teamed up with colleagues from Canada, the U.S., Japan, France, and Germany...
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Selective inhibition of matrix metalloproteinase 10 with a single-domain antibody

7 days ago   |   ACS Division of Biological Chemistry

Since their discovery, the matrix metalloproteinase family of proteases have been considered as therapeutic targets in numerous diseases and disorders. Unfortunately, clinical...
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Why can't Bertrand Might cry? Scientists offer an answer: missing water channels

9 days ago   |   San Diego Biotechnology

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that cells from children with NGLY1 deficiency-a rare disorder first described in 2012-lack...
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Emendo Biotherapeutics Nabs $61M for “Next-Generation CRISPR” R&D

Emendo Biotherapeutics Nabs $61M for “Next-Generation CRISPR” R&D

10 days ago   |   Xconomy

Emendo Biotherapeutics, a company aiming to apply CRISPR gene editing to a wider range of genetic diseases, has raised $61 million in financing. The Series B round was led by...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Kaitlyn Waters

IAmScience Kaitlyn Waters

By Mariah Cox | Bond LSC It's common knowledge that all Ph.D. candidates must complete research in preparation for a dissertation, but what happens when one's faculty mentor... Read more ...

Alumni Spotlight: Barry A. Johnson

Alumni Spotlight: Barry A. Johnson

Barry Johnson with his son and daughter. Barry Johnson '87 had a great experience at the university while working on his Bachelor's degree in Agricultural Engineering. Johnson... Read more ...

Bio Roundup: Coronavirus Concerns, Sarepta's CRL, Eye Drug OK'd & More

Bio Roundup: Coronavirus Concerns, Sarepta's CRL, Eye Drug OK'd & More

Company news slowed somewhat this week, perhaps as some took the federal Martin Luther King Jr. Day holiday away from the office and others recovered from back-to-back meetings... Read more ...

Q&A With Eric Seaborg: Science Writer, Author, and Outdoorsman

Q&A With Eric Seaborg: Science Writer, Author, and Outdoorsman

Eric Seaborg Eric Seaborg, a writer and author, outdoorsman and environmentalist, has a love for hiking that he shared with his father, the late chemist and Nobel laureate... Read more ...

Project to Rapidly Sequence Maize Pangenome Delivers Publicly Available Resource

Project to Rapidly Sequence Maize Pangenome Delivers Publicly Available Resource

Matt Hufford, associate professor at Iowa State University, helped produce a 26-line maize pangenome assembly collection Maize researchers have been rejoicing over a New Year's... Read more ...

Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

Epizyme won accelerated FDA approval Thursday for a drug developed to treat the rare cancer epithelioid sarcoma. The regulatory decision for the Epizyme drug, tazemetostat... Read more ...

CUBIC: an atlas of genetic architecture promises directed maize improvement

Identifying genotype-phenotype links and causative genes from quantitative trait loci is challenging for complex agronomically important traits. To accelerate maize gene... Read more ...

Co-opted transposons help perpetuate conserved higher-order chromosomal...

Transposable elements make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include binding sites for... Read more ...

Why eating yogurt may help lessen the risk of breast cancer

One of the causes of breast cancer may be inflammation triggered by harmful bacteria suggest researchers. Scientists advise consuming natural yogurt, which contains beneficial... Read more ...

Why cells need acidic lysosomes

Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to... Read more ...