Protein

Characterization of the peroxiredoxin 1 subfamily from Tetrahymena thermophila

23 days ago   |   By Springer

Abstract
Peroxiredoxins are antioxidant enzymes that use redox active Cys residues to reduce H 2 O 2 and various organic hydroperoxides to less reactive products, and thereby protect cells against oxidative stress. In yeasts and mammals, the Prx1 proteins are sensitive to hyperoxidation and consequent loss of their peroxidase activity whereas in most bacteria they are not. In this paper we report the characterization of the Prx1 family in the non-parasitic protist Tetrahymena thermophila. In this organism, four genes potentially encoding Prx1 have been identified. In particular, we show...
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