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BMC Bioinformatics

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SVNN: AN EFFICIENT PACBIO-SPECIFIC PIPELINE FOR STRUCTURAL VARIATIONS CALLING USING NEURAL NETWORKS

Once aligned, long-reads can be a useful source of information to identify the type and position of structural variations. However,...

ORFIK: A COMPREHENSIVE R TOOLKIT FOR THE ANALYSIS OF TRANSLATION

With the rapid growth in the use of high-throughput methods for characterizing translation and the continued expansion of multi-omics,...

 
 
 

SIMULATION STUDY AND COMPARATIVE EVALUATION OF VIRAL CONTIGUOUS SEQUENCE IDENTIFICATION TOOLS

Viruses, including bacteriophages, are important components of environmental and human associated microbial communities. Viruses can...

MACHINE LEARNING-BASED PREDICTION OF SURVIVAL PROGNOSIS IN CERVICAL CANCER

Accurately forecasting the prognosis could improve cervical cancer management, however, the currently used clinical features are difficult...

 
 
 

A MACHINE LEARNING FRAMEWORK THAT INTEGRATES MULTI-OMICS DATA PREDICTS CANCER-RELATED LNCRNAS

LncRNAs are a type of non-coding RNA molecule with transcript length longer than 200 nucleotides. LncRNA has been novel candidate biomarkers...

PREDICTION OF UNCONVENTIONAL PROTEIN SECRETION BY EXOSOMES

In eukaryotes, proteins targeted for secretion contain a signal peptide, which allows them to proceed through the conventional ER/Golgi-dependent...

 
 
 

APPLICATION OF CONVOLUTIONAL NEURAL NETWORKS TOWARDS NUCLEI SEGMENTATION IN LOCALIZATION-BASED SUPER-RESOLUTION FLUORESCENCE MICROSCOPY IMAGES

Automated segmentation of nuclei in microscopic images has been conducted to enhance throughput in pathological diagnostics and biological...

IOAT: AN INTERACTIVE TOOL FOR STATISTICAL ANALYSIS OF OMICS DATA AND CLINICAL DATA

With the development of high-throughput sequencing technology, a huge amount of multi-omics data has been accumulated. Although there...

 
 
 

MULTI-LABELLED PROTEINS RECOGNITION FOR HIGH-THROUGHPUT MICROSCOPY IMAGES USING DEEP CONVOLUTIONAL NEURAL NETWORKS

Proteins are of extremely vital importance in the human body, and no movement or activity can be performed without proteins. Currently,...

CORRECTION TO: AN INTRODUCTION TO NEW ROBUST LINEAR AND MONOTONIC CORRELATION COEFFICIENTS

An amendment to this paper has been published and can be accessed via the original article.

 
 
 

NUCOME: A COMPREHENSIVE DATABASE OF NUCLEOSOME ORGANIZATION REFERENCED LANDSCAPES IN MAMMALIAN GENOMES

Nucleosome organization is involved in many regulatory activities in various organisms. However, studies integrating nucleosome organization...

CHEMICAL MAP-BASED PREDICTION OF NUCLEOSOME POSITIONING USING THE BIOCONDUCTOR PACKAGE NUCPOS

Assessing the nucleosome-forming potential of specific DNA sequences is important for understanding complex chromatin organization....

 
 
 

INCREASED PEAK DETECTION ACCURACY IN OVER-DISPERSED CHIP-SEQ DATA WITH SUPERVISED SEGMENTATION MODELS

Histone modification constitutes a basic mechanism for the genetic regulation of gene expression. In early 2000s, a powerful technique...

PREDICTING BIOLOGICAL PATHWAYS OF CHEMICAL COMPOUNDS WITH A PROFILE-INSPIRED APPROACH

Assignment of chemical compounds to biological pathways is a crucial step to understand the relationship between the chemical repertory...

 
 
 

NOVEL DEEP LEARNING-BASED TRANSCRIPTOME DATA ANALYSIS FOR DRUG-DRUG INTERACTION PREDICTION WITH AN APPLICATION IN DIABETES

Drug-drug interaction is a serious public health issue. The L1000 database of the LINCS project has collected millions of genome-wide...

CORRECTION TO: EYE‑COLOR AND TYPE‑2 DIABETES PHENOTYPE PREDICTION FROM GENOTYPE DATA USING DEEP LEARNING METHODS

An amendment to this paper has been published and can be accessed via the original article.

 
 
 

FORECASTING THE SPREAD OF COVID-19 USING LSTM NETWORK

The novel coronavirus is caused by severe acute respiratory syndrome coronavirus 2, and within a few months, it has become a global...

PPALIGN: OPTIMAL ALIGNMENT OF POTTS MODELS REPRESENTING PROTEINS WITH DIRECT COUPLING INFORMATION

To assign structural and functional annotations to the ever increasing amount of sequenced proteins, the main approach relies on sequence-based...

 
 
 

EXPANDING THE TAXONOMIC RANGE IN THE FECAL METAGENOME

Except for bacteria, the taxonomic diversity of the human fecal metagenome has not been widely studied, despite the potential importance...

EXPLORING THE FUNCTIONAL COMPOSITION OF THE HUMAN MICROBIOME USING A HAND-CURATED MICROBIAL TRAIT DATABASE

Even when microbial communities vary wildly in their taxonomic composition, their functional composition is often surprisingly stable....

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

DermTech to Partner with University of Barcelona for Research Study on...

LA JOLLA, Calif.--DermTech, Inc. , a leader in precision dermatology enabled by a non-invasive skin genomics platform, announced today a collaboration with researchers from the... Read more ...

Switching from Western diet to a balanced diet may reduce skin, joint...

Diet rich in sugar and fat leads to disruption in the gut's microbial culture and contributes to inflammatory skin diseases such as psoriasis. Research shows that switching to... Read more ...

Some seafloor microbes can take the heat: And here's what they eat

In two new studies on life in the seafloor of the Guaymas Basin, in the Gulf of California, scientists show that distinct regions within the Basin harbor specially adapted... Read more ...

Flash mob in the nucleus

The nucleus is much more than a storage compartment for chromosomes: It also contains the complex machinery producing transcripts of the genes that are currently needed and... Read more ...

Alchemab's new well-connected CEO will lead biotech on journey to address...

Alchemab's new well-connected CEO will lead biotech on journey to address hard-to-treat diseases aarmstrong Tue, 06/22/2021 - 10:03 Read more ...

Ready, set, go - how stem cells synchronize to repair the spinal cord in...

Few animals can regenerate their spinal cord after an injury. The axolotl can mobilize stem cells in its spinal cord to regrow the lost tissue. An international team of... Read more ...

Cohesin opens up for cell division

Scientists have uncovered a mechanism that allows a protein complex to bind to DNA without impeding some of the important processes of cell division. Their findings could... Read more ...

Illuminating the mechanism behind how plants regulate starch synthesis

Biologists have used rice to successfully illuminate the mechanism by which plants regulate the amount of starch produced via photosynthesis. This knowledge could contribute... Read more ...

Halozyme Announces Janssen Receives European Marketing Authorizations for...

SAN DIEGO: SAN DIEGO, June 22, 2021 /PRNewswire/ - Halozyme Therapeutics, Inc. today announced that the European Commission has granted the Janssen Pharmaceutical Companies of... Read more ...

Iris and Matthew Strauss Give $2 Million to Endow Faculty Chair at UC San Diego

Iris and Matthew Strauss Give $2 Million to Endow Faculty Chair at UC San Diego

Longtime supporters of cancer research and patient care at Moores Cancer Center at UC San Diego Health have given University of California San Diego School of Medicine $2... Read more ...