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BMC Bioinformatics

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BEST: A WEB SERVER FOR BRAIN EXPRESSION SPATIO-TEMPORAL PATTERN ANALYSIS

Dysregulated gene expression patterns have been reported in several mental disorders. Limited by the difficulty of obtaining samples,...

IMMUNE REPERTOIRE FINGERPRINTING BY PRINCIPAL COMPONENT ANALYSIS REVEALS SHARED FEATURES IN SUBJECT GROUPS WITH COMMON EXPOSURES

Advances in next-generation sequencing of antibody repertoires have led to an explosion in B cell receptor sequence data from donors...

 
 
 

AN IMPROVED RANDOM FOREST-BASED COMPUTATIONAL MODEL FOR PREDICTING NOVEL MIRNA-DISEASE ASSOCIATIONS

A large body of evidence shows that miRNA regulates the expression of its target genes at post-transcriptional level and the dysregulation...

IDENTIFYING GENE-SPECIFIC SUBGROUPS: AN ALTERNATIVE TO BICLUSTERING

Transcriptome analysis aims at gaining insight into cellular processes through discovering gene expression patterns across various...

 
 
 

A NOVEL TARGET CONVERGENCE SET BASED RANDOM WALK WITH RESTART FOR PREDICTION OF POTENTIAL LNCRNA-DISEASE ASSOCIATIONS

In recent years, lncRNAs have been proved to be closely related to the occurrence and development of many serious diseases that are...

RELATION EXTRACTION BETWEEN BACTERIA AND BIOTOPES FROM BIOMEDICAL TEXTS WITH ATTENTION MECHANISMS AND DOMAIN-SPECIFIC CONTEXTUAL REPRESENTATIONS

The Bacteria Biotope task is a biomedical relation extraction that aims to study the interaction between bacteria and their locations....

 
 
 

A HYBRID DEEP LEARNING FRAMEWORK FOR BACTERIAL NAMED ENTITY RECOGNITION WITH DOMAIN FEATURES

Microbes have been shown to play a crucial role in various ecosystems. Many human diseases have been proved to be associated with bacteria,...

A DISEASE-RELATED GENE MINING METHOD BASED ON WEAKLY SUPERVISED LEARNING MODEL

Predicting disease-related genes is helpful for understanding the disease pathology and the molecular mechanisms during the disease...

 
 
 

VIRTUAL GRID ENGINE: A SIMULATED GRID ENGINE ENVIRONMENT FOR LARGE-SCALE SUPERCOMPUTERS

Supercomputers have become indispensable infrastructures in science and industries. In particular, most state-of-the-art scientific...

EXPLORING THE 2D AND 3D STRUCTURAL PROPERTIES OF TOPOLOGICALLY ASSOCIATING DOMAINS

Topologically associating domains are genomic regions with varying lengths. The interactions within TADs are more frequent than those...

 
 
 

DELTARPKM: AN R PACKAGE FOR A RAPID DETECTION OF DIFFERENTIAL GENE PRESENCE BETWEEN RELATED BACTERIAL GENOMES

Comparative genomics has seen the development of many software performing the clustering, polymorphism and gene content analysis of...

AMON: ANNOTATION OF METABOLITE ORIGINS VIA NETWORKS TO INTEGRATE MICROBIOME AND METABOLOME DATA

Untargeted metabolomics of host-associated samples has yielded insights into mechanisms by which microbes modulate health. However,...

 
 
 

DETECTION OF BIOLOGICAL SWITCHES USING THE METHOD OF GRÖEBNER BASES

Bistability and ability to switch between two stable states is the hallmark of cellular responses. Cellular signaling pathways often...

CORRECTION TO: PREDICTING PROTEIN INTER-RESIDUE CONTACTS USING COMPOSITE LIKELIHOOD MAXIMIZATION AND DEEP LEARNING

Following publication of the original article , the author explained that there are several errors in the original article

 
 
 

HKPOCKET: HUMAN KINASE POCKET DATABASE FOR DRUG DESIGN

The kinase pocket structural information is important for drug discovery targeting cancer or other diseases. Although some kinase sequence,...

POTENTIAL BASED, SPATIAL SIMULATION OF DYNAMICALLY NESTED PARTICLES

To study cell biological phenomena which depend on diffusion, active transport processes, or the locations of species, modeling and...

 
 
 

ATTENTION MECHANISM ENHANCED LSTM WITH RESIDUAL ARCHITECTURE AND ITS APPLICATION FOR PROTEIN-PROTEIN INTERACTION RESIDUE PAIRS PREDICTION

Recurrent neural network is a good way to process sequential data, but the capability of RNN to compute long sequence data is inefficient....

MANHATTAN++: DISPLAYING GENOME-WIDE ASSOCIATION SUMMARY STATISTICS WITH MULTIPLE ANNOTATION LAYERS

Over the last 10 years, there have been over 3300 genome-wide association studies. Almost every GWAS study provides a Manhattan plot...

 
 
 

A GENERAL-PURPOSE SIGNAL PROCESSING ALGORITHM FOR BIOLOGICAL PROFILES USING ONLY FIRST-ORDER DERIVATIVE INFORMATION

Automatic signal-feature extraction algorithms are crucial for profile processing in bioinformatics. Both baseline drift and noise...

HIERARCHICAL CLUSTERING OF MAXIMUM PARSIMONY RECONCILIATIONS

Maximum parsimony reconciliation in the duplication-transfer-loss model is a widely-used method for analyzing the evolutionary histories...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Mannie Liscum

IAmScience Mannie Liscum

For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...

Pineoblastoma segregates into molecular sub-groups with distinct...

Abstract Pineoblastomas are rare, aggressive pediatric brain tumors of the pineal gland with modest overall survival despite intensive therapy. We sought to define the clinical... Read more ...

The majority of A-to-I RNA editing is not required for mammalian homeostasis

Abstract Background Adenosine-to-inosine RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I... Read more ...

CRISPR System: A High-throughput Toolbox for Research and Treatment of...

Abstract In recent years, the innovation of gene-editing tools such as the CRISPR/Cas9 system improves the translational gap of treatments mediated by gene therapy. The... Read more ...

Exploration of cryptic organic photosensitive compound as Zincphyrin IV in...

Abstract Zincphyrin IV is a potential organic photosensitizer which is of significant interest for applications in biomedicine, materials science, agriculture , and chemistry... Read more ...

Three transcriptional regulators positively regulate the biosynthesis of...

Abstract Polycyclic tetramate macrolactams are a widely distributed class of structurally complex natural products, and most of them exhibit multiple biological activities... Read more ...

Faint gray bands in Drosophila melanogaster polytene chromosomes are formed...

Abstract In Drosophila melanogaster , the chromatin of interphase polytene chromosomes appears as alternating decondensed interbands and dense black or thin gray bands... Read more ...

A New Risk-Based Fuzzy Cognitive Model and Its Application to Decision-Making

Abstract Cognitive information in real-world decision-making problems is usually associated with all sorts of ambiguities and uncertainties. Fuzzy sets have been proposed as a... Read more ...

Analyzing the action of evolutionarily conserved modules on HMW-GS 1Ax1...

Abstract Key message The specific and high-level expression of 1Ax1 is determined by different promoter regions. HMW-GS synthesis occurs in aleurone layer cells. Heterologous... Read more ...

Achromobacter sp. FB-14 harboring ACC deaminase activity augmented rice...

Abstract Soil salinity is one of the major plant growth and yield-limiting constraints in arid and semi-arid regions of the world. In addition to the oxidative damage... Read more ...