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Journal of Biosciences

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AN RNAI-INDEPENDENT ROLE OF AP1-LIKE STRESS RESPONSE FACTOR PAP1 IN CENTROMERE AND MATING-TYPE SILENCING IN SCHIZOSACCAROMYCES POMBE

Abstract Gene silencing in S. pombe occurs by heterochromatin formation at the centromere , mating-type and telomere loci. It is mediated...

IDENTIFICATION OF UNIQUE SUBTYPE-SPECIFIC INTERACTION FEATURES IN CLASS II ZINC-DEPENDENT HDAC SUBTYPE BINDING POCKETS: A COMPUTATIONAL STUDY

Abstract Zinc-dependent HDAC subtypes exhibit differential expression in various cancer types and significantly contribute to oncogenic...

 
 
 

CHANGES IN MIR 21 AND 23B EXPRESSION IN POSTNATAL HYPERTROPHIC HEART DERIVED FROM GESTATIONAL DIABETES PRECEDE DILATED CARDIOMYOPATHY

Abstract Gestational diabetes mellitus increases the risk of fetal congenital ventricular hypertrophic cardiomyopathy. We explored...

METASTABLE BIOMOLECULAR CONDENSATES OF INTERFERON-INDUCIBLE ANTIVIRAL MX-FAMILY GTPASES: A PARADIGM SHIFT IN THE LAST THREE YEARS

Abstract Membraneless organelles in the cytoplasm and nucleus in the form of phase-separated biomolecular condensates are increasingly...

 
 
 

INFLUENCE OF NNAV1.5 ON MHC CLASS I EXPRESSION IN BREAST CANCER

Abstract Cancer metastasis occurs due to the ability of the tumour to evade immune recognition and response by altering the major histocompatibility...

EXOSOMAL CIRCRNA HIPK3 KNOCKDOWN INHIBITED CELL PROLIFERATION AND METASTASIS IN PROSTATE CANCER BY REGULATING MIR-212/BMI-1 PATHWAY

Abstract Prostate cancer is the second frequent malignancy among men in the world. Exosomal circular RNAs have been reported to function...

 
 
 

PROGNOSTIC VALUE AND IMMUNOLOGICAL CHARACTERISTICS OF A NOVEL AUTOPHAGY-RELATED SIGNATURE IN PANCREATIC CANCER

Abstract Autophagy affects the development, progression, and prognosis of various cancers including pancreatic cancer. To develop an...

IN VITRO ACTIVITY OF RECONSTITUTED RUBISCO ENZYME FROM GLOEOBACTER VIOLACEUS

Abstract RuBisCO (Ribulose 1,5 bisphosphate carboxylase/oxygenase) by virtue of its dual specificity towards oxygen and carbon dioxide...

 
 
 

CIRCRNA DERIVED FROM CLSPN IS AN ONCOGENE IN HUMAN GLIOBLASTOMA MULTIFORME BY REGULATING CELL GROWTH, MIGRATION AND INVASION VIA CERNA PATHWAY

Abstract Glioblastoma multiforme is the most aggressive and prevalent brain tumor in adults. The circRNA derived from CLSPN is remarkably...

N-3--L-HOMOSERINE LACTONE SUPPRESSES DENDRITIC CELL MATURATION BY UPREGULATING THE LONG NONCODING RNA NRIR

Abstract N -3--l-homoserine lactone , a small bacterial signaling molecule secreted by Pseudomonas aeruginosa , can block dendritic...

 
 
 

PSYCHROPHILES: A JOURNEY OF HOPE

Abstract Psychrophiles are organisms living in extremely cold conditions within the temperature range of −20°C to + 10°C. These organisms...

IL-3 INHIBITS RAT OSTEOCLAST DIFFERENTIATION INDUCED BY TNF-Α AND OTHER PRO-OSTEOCLASTOGENIC CYTOKINES

Abstract IL-3, a haematopoiesis regulatory factor, has previously been shown to inhibit both mouse and human osteoclast differentiation...

 
 
 

TEACH, TRAIN AND TEST: LABORATORY EXERCISES USING FLIES

MULTIPLE ALLELIC ASSOCIATIONS FROM GENES INVOLVED IN ENERGY METABOLISM WERE IDENTIFIED IN CELIAC DISEASE

Abstract Energy metabolism is a critical factor that influences disease pathogenesis. Recent high-throughput genomic studies have enabled...

 
 
 

TARGET OF RAPAMYCIN GENE IS VITAL FOR WHITEFLY SURVIVAL AND REPRODUCTION

Abstract The whitefly Bemisia tabaci is a devastating polyphagous pest that causes significant losses in several economically important...

THE BOSCOMBE VALLEY MYSTERY: A LESSON IN THE PERILS OF DOGMATISM IN SCIENCE

Abstract The central dogma enunciated by Francis Crick and the postulate that sequence defines protein structure and function put forth...

 
 
 

DETERMINATION OF ANTIOXIDANT CAPACITY AND FLAVONOID COMPOSITION OF ONION LANDRACE ‘KRISHNAPURAM' BULB USING HPLC-ESI-ITMS

Abstract This study reports for the first-time antioxidant activity and flavonoid composition of KP onion landrace which is useful...

TRIGLYCERIDE REGULATE ACE2 LEVEL THROUGH MTHFD1

Abstract Obesity has been followed with interest as a risk factor for COVID-19, with triglycerides as one of four common criteria used...

 
 
 

PD BIBIM: BICLUSTERING-BASED BIOMARKER IDENTIFICATION IN ESCC MICROARRAY DATA

Abstract To promote diligent analysis of the progression of a disease, it is important to identify interesting biomarkers for the disease....

EXPLORING THE SIGNATURE GUT AND ORAL MICROBIOME IN INDIVIDUALS OF SPECIFIC AYURVEDA PRAKRITI

Abstract Diagnosis and treatment of various diseases in Ayurveda , the Indian system of medicine, relies on ‘ prakriti ' phenotyping...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

MicroRNA-17-5p Promotes Cardiac Hypertrophy by Targeting Mfn2 to Inhibit...

Abstract Pathological cardiac hypertrophy is the leading cause of heart failure, and miRNAs have been recognized as key factors in cardiac hypertrophy. This study aimed to... Read more ...

Scientist, Hematologic and Immunologic Toxicology - La Jolla, CA - Johnson &...

As part of the cutting-edge Global Predictive, Investigative and Translational Toxicology Team, the candidate will have the opportunity to work within...From Johnson & Johnson... Read more ...

Bringing Protection Back in Line

Bringing Protection Back in Line

Research refines platform to address immune disorders Dr. Esma Yolcu and Dr. Haval Shirwan, Co-pioneers of ProtEx technology By Davis Suppes | Bond LSC The things that protect... Read more ...

After 40 Years, HIV Presents Research Problems New and Old

After 40 Years, HIV Presents Research Problems New and Old

In the years since AIDS was first described in medical research, the scientific map of that disease has changed enormously. Once it was relatively empty. Now scientists... Read more ...

Exosomal circRNA HIPK3 knockdown inhibited cell proliferation and metastasis...

Abstract Prostate cancer is the second frequent malignancy among men in the world. Exosomal circular RNAs have been reported to function in PCa progression. The current study... Read more ...

Prognostic value and immunological characteristics of a novel...

Abstract Autophagy affects the development, progression, and prognosis of various cancers including pancreatic cancer. To develop an autophagy-related prognostic model of... Read more ...

Chiral nanomaterials for tumor therapy: autophagy, apoptosis, and...

Chirality is a fundamental characteristic of natural molecules and a crucial factor in the biochemical reactions of living cells and organisms. Recently, researchers have... Read more ...

Ramil the snow leopard tests positive for COVID at the San Diego Zoo

Zoo staff say the animal's symptoms are mild and are still investigating how he got infected Read more ...

Enhanced lignin biodegradation by consortium of white rot fungi: microbial...

As one of the major components of lignocellulosic biomass, lignin has been considered as the most abundant renewable aromatic feedstock in the world. Comparing with thermal or... Read more ...

Design and heterologous expression of a novel dimeric LL37 variant in Pichia...

The antimicrobial peptide LL37 is produced by white blood cells and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing... Read more ...