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Microbial Cell Factories

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EXPRESSION, HOMOLOGY MODELING AND ENZYMATIC CHARACTERIZATION OF A NEW Β-MANNANASE BELONGING TO GLYCOSIDE HYDROLASE FAMILY 1 FROM ENTEROBACTER AEROGENES B19

Β-mannanase can hydrolyze β-1,4 glycosidic bond of mannan by the manner of endoglycosidase to generate mannan-oligosaccharides. Currently,...

DE NOVO RESVERATROL PRODUCTION THROUGH MODULAR ENGINEERING OF AN ESCHERICHIA COLI-SACCHAROMYCES CEREVISIAE CO-CULTURE

Resveratrol is a plant secondary metabolite with diverse, potential health-promoting benefits. Due to its nutraceutical merit, bioproduction...

 
 
 

IN VIVO CREATION OF PLASMID PCRT01 AND ITS USE FOR THE CONSTRUCTION OF CAROTENOID-PRODUCING PARACOCCUS SPP. STRAINS THAT GROW EFFICIENTLY ON INDUSTRIAL WASTES

Carotenoids are natural tetraterpene pigments widely utilized in the food, pharmaceutical and cosmetic industries. Currently, chemical...

DESIGN AND DEVELOPMENT OF A CHIMERIC VACCINE CANDIDATE AGAINST ZOONOTIC HEPATITIS E AND FOOT-AND-MOUTH DISEASE

Zoonotic hepatitis E virus infection emerged as a serious threat in the industrialized countries. The aim of this study is exploring...

 
 
 

THE INFLUENCE OF TRANSKETOLASE ON LIPID BIOSYNTHESIS IN THE YEAST YARROWIA LIPOLYTICA

During the pentose phosphate pathway , two important components, NADPH and pentoses, are provided to the cell. Previously it was shown...

NUCLEIC ACIDS IN INCLUSION BODIES OBTAINED FROM E. COLI CELLS EXPRESSING HUMAN INTERFERON-GAMMA

Inclusion bodies are protein aggregates in recombinant bacterial cells containing mainly the target recombinant protein. Although it...

 
 
 

MOLECULAR CHARACTERIZATION AND HETEROLOGOUS EXPRESSION OF TWO Α-GLUCOSIDASES FROM METSCHNIKOWIA SPP, BOTH PRODUCERS OF HONEY SUGARS

Α-Glucosidases are widely distributed enzymes with a varied substrate specificity that are traditionally used in biotechnological industries...

A PROGRAMMABLE CRISPR/CAS9-BASED PHAGE DEFENSE SYSTEM FOR ESCHERICHIA COLI BL21

Escherichia coli BL21 is arguably the most popular host for industrial production of proteins, and industrial fermentations are often...

 
 
 

AN ALTERNATIVE FOR PROTEINASE K-HEAT-SENSITIVE PROTEASE FROM FUNGUS ONYGENA CORVINA FOR BIOTECHNOLOGY: CLONING, ENGINEERING, EXPRESSION, CHARACTERIZATION AND SPECIAL APPLICATION FOR PROTEIN SEQUENCING

A neutral, heat-sensitive serine protease originating from the feather-degrading fungus Onygena corvina was described and defined as...

ENHANCED MULTI-STRESS TOLERANCE AND GLUCOSE UTILIZATION OF SACCHAROMYCES CEREVISIAE BY OVEREXPRESSION OF THE SNF1 GENE AND VARIED BETA ISOFORM OF SNF1 DOMINATES IN STRESSES

The Saccharomyces cerevisiae Snf1 complex is a member of the AMP-activated protein kinase family and plays an important role in response...

 
 
 

BIOSURFACTANT FROM VAGINAL LACTOBACILLUS CRISPATUS BC1 AS A PROMISING AGENT TO INTERFERE WITH CANDIDA ADHESION

Lactobacillus spp. dominating the vaginal microbiota of healthy women contribute to the prevention of urogenital and sexually transmitted...

IDENTIFICATION AND CHARACTERIZATION OF A MOONLIGHTING PROTEIN-ENOLASE FOR SURFACE DISPLAY IN STREPTOCOCCUS THERMOPHILUS

Streptococcus thermophilus is an important food starter and receiving more attention to serve as cell factories for production of high-valued...

 
 
 

METABOLIC ROLE OF PYROPHOSPHATE-LINKED PHOSPHOFRUCTOKINASE PFK FOR C1 ASSIMILATION IN METHYLOTUVIMICROBIUM ALCALIPHILUM 20Z

Methanotrophs is a promising biocatalyst in biotechnological applications with their ability to utilize single carbon feedstock to...

METABOLIC ENGINEERING OF ESCHERICHIA COLI FOR EFFICIENT PRODUCTION OF L-ALANYL-L-GLUTAMINE

L-Alanyl-l-glutamine is a functional dipeptide with high water solubility, good thermal stability and high bioavailability. It is widely...

 
 
 

GLUTEN HYDROLYZING ACTIVITY OF BACILLUS SPP ISOLATED FROM SOURDOUGH

Celiac disease is an intestinal chronic disorder with multifactorial etiology resulting in small intestinal mucosal injuries and malabsorption....

DNA STEGANOGRAPHY: HIDING UNDETECTABLE SECRET MESSAGES WITHIN THE SINGLE NUCLEOTIDE POLYMORPHISMS OF A GENOME AND DETECTING MUTATION-INDUCED ERRORS

As cell engineering technology advances, more complex synthetically designed cells and metabolically engineered cells are being developed....

 
 
 

A GLUCOTOLERANT Β-GLUCOSIDASE FROM THE FUNGUS TALAROMYCES AMESTOLKIAE AND ITS CONVERSION INTO A GLYCOSYNTHASE FOR GLYCOSYLATION OF PHENOLIC COMPOUNDS

The interest for finding novel β-glucosidases that can improve the yields to produce second-generation biofuels is still very high....

HIGHLY ENANTIOSELECTIVE SYNTHESIS OF -1,3-BUTANEDIOL VIA DERACEMIZATION OF THE CORRESPONDING RACEMATE BY A WHOLE-CELL STEREOINVERTING CASCADE SYSTEM

Deracemization, the transformation of the racemate into a single stereoisomeric product in 100% theoretical yield, is an appealing...

 
 
 

DEVELOPMENT OF A NEW GENE EXPRESSION VECTOR FOR THERMUS THERMOPHILUS USING A SILICA-INDUCIBLE PROMOTER

Thermostable enzymes are commonly produced in mesophilic hosts for research and bioengineering purposes. However, these hosts do not...

A NEW GENERATION OF RECOMBINANT POLYPEPTIDES COMBINES MULTIPLE PROTEIN DOMAINS FOR EFFECTIVE ANTIMICROBIAL ACTIVITY

Although most of antimicrobial peptides , being relatively short, are produced by chemical synthesis, several AMPs have been produced...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

After Biologic COVID-19 Drug OK'd in India, Equillium Plans a US Test

The drug that Equillium licensed from India-based pharma giant Biocon has received authorization for emergency use in that country in patients hospitalized with COVID-19. The... Read more ...

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

Roche, Blueprint Medicines Team Up Again in $775M RET Cancer Drug Pact

A Blueprint Medicines cancer drug candidate currently under FDA review will have the marketing muscle of Roche behind it if it wins regulatory approval. The two companies are... Read more ...

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Last Chance for Xconomy Awards Nominations - Deadline is Friday, July 17

Have you had your say yet? The 2020 National Xconomy Awards represent the very best our life science industry has to offer. It is our privilege to recognize emerging companies... Read more ...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on...

New Xconomy Podcast & Special Report Feature Boston Biophama Leaders on Digital Health

Miss Xconomy's Xcelerating Life Sciences Boston: Biopharma's Future in Digital Health event or want to revisit the insightful content? Our new podcast and special report... Read more ...

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

Amgen Doubles Down on BeiGene Collaboration, Investing $421M More

At the year's start Thousand Oaks, CA-based Amgen closed a strategic collaboration with BeiGene, investing $2.8 billion to gain a presence in what's becoming an ever-more... Read more ...

Scientists Successfully Demonstrate a New Experiment in the Search for...

Scientists Successfully Demonstrate a New Experiment in the Search for Theorized ‘Neutrinoless' Process

The CUPID-Mo detector is installed in the Edelweiss cryostat at Modane Underground Laboratory in France. Nuclear physicists affiliated with the U.S. Department of Energy's... Read more ...

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

3 Biotech IPOs Together Rake In Over a Half Billion to Advance Treatments

Three biotech companies collectively raised $584 million in their initial public offerings last week, continuing a streak of IPOs that has the healthcare sector playing a... Read more ...

Expression, homology modeling and enzymatic characterization of a new...

Β-mannanase can hydrolyze β-1,4 glycosidic bond of mannan by the manner of endoglycosidase to generate mannan-oligosaccharides. Currently, β-mannanase has been widely applied... Read more ...

De novo resveratrol production through modular engineering of an Escherichia...

Resveratrol is a plant secondary metabolite with diverse, potential health-promoting benefits. Due to its nutraceutical merit, bioproduction of resveratrol via microbial... Read more ...

From monomer to fibril: Abeta‐amyloid binding to Aducanumab antibody studied...

Abstract Alzheimer's disease is one of the most common causes of dementia. It is believed that the aggregation of short Aβ‐peptides to form oligomeric and protofibrillar... Read more ...