THE QBED TRACK: A NOVEL GENOME BROWSER VISUALIZATION FOR POINT PROCESSES

AbstractSummaryTransposon calling cards is a genomic assay for identifying transcription factor binding sites in both bulk and single...

NEOANTIMON: A MULTIFUNCTIONAL R PACKAGE FOR IDENTIFICATION OF TUMOR-SPECIFIC NEOANTIGENS

AbstractSummaryIt is known that some mutant peptides, such as those resulting from missense mutations and frameshift insertions, can...

 
 
 

GENE CIRCUIT EXPLORER : AN INTERACTIVE WEB-APP FOR VISUALIZING, SIMULATING AND ANALYZING GENE REGULATORY CIRCUITS

AbstractSummaryGeneEx is an interactive web-app that employs an ODE-based mathematical modeling approach to simulate, visualize, and...

COGENT: EVALUATING THE CONSISTENCY OF GENE CO-EXPRESSION NETWORKS

AbstractSummaryGene co-expression networks can be constructed in multiple different ways, both in the use of different measures of...

 
 
 

AFID: A TOOL FOR AUTOMATED IDENTIFICATION AND EXCLUSION OF AUTOFLUORESCENT OBJECTS FROM MICROSCOPY IMAGES

AbstractMotivationAutofluorescence is a long-standing problem that has hindered the analysis of images of tissues acquired by fluorescence...

SEEDS: DATA DRIVEN INFERENCE OF STRUCTURAL MODEL ERRORS AND UNKNOWN INPUTS FOR DYNAMIC SYSTEMS BIOLOGY

AbstractSummaryDynamic models formulated as ordinary differential equations can provide information about the mechanistic and causal...

 
 
 

HISCF: LEVERAGING HIGHER-ORDER STRUCTURES FOR CLUSTERING ANALYSIS IN BIOLOGICAL NETWORKS

AbstractMotivationClustering analysis in a biological network is to group biological entities into functional modules, thus providing...

INFERENCE OF VIRAL QUASISPECIES WITH A PAIRED DE BRUIJN GRAPH

AbstractMotivationRNA viruses exhibit a high mutation rate and thus they exist in infected cells as a population of closely related...

 
 
 

PCAMATCHR: A FLEXIBLE R PACKAGE FOR OPTIMAL CASE-CONTROL MATCHING USING WEIGHTED PRINCIPAL COMPONENTS

AbstractSummaryA concern when conducting genome-wide association studies is the potential for population stratification, i.e. ancestry...

CHESPA/CHESCA-SPARKY: AUTOMATED NMR DATA ANALYSIS PLUGINS FOR SPARKY TO MAP PROTEIN ALLOSTERY

AbstractMotivationCorrelated NMR chemical shift changes identified through the CHEmical Shift Projection Analysis and CHEmical Shift...

 
 
 

ANNOTATING HIGH-IMPACT 5'UNTRANSLATED REGION VARIANTS WITH THE UTRANNOTATOR

AbstractSummaryCurrent tools to annotate the predicted effect of genetic variants are heavily biased towards protein-coding sequence....

SHARK: FISHING RELEVANT READS IN AN RNA-SEQ SAMPLE

AbstractMotivationRecent advances in high throughput RNA-Seq technologies allow to produce massive datasets. When a study focuses only...

 
 
 

FAST GAP-AFFINE PAIRWISE ALIGNMENT USING THE WAVEFRONT ALGORITHM

AbstractMotivationPairwise alignment of sequences is a fundamental method in modern molecular biology, implemented within multiple...

INCORPORATING PRIOR KNOWLEDGE INTO REGULARIZED REGRESSION

AbstractMotivationAssociated with genomic features like gene expression, methylation, and genotypes, used in statistical modeling of...

 
 
 

MR-CLUST: CLUSTERING OF GENETIC VARIANTS IN MENDELIAN RANDOMIZATION WITH SIMILAR CAUSAL ESTIMATES

AbstractMotivationMendelian randomization is an epidemiological technique that uses genetic variants as instrumental variables to estimate...

EPIDOPE: A DEEP NEURAL NETWORK FOR LINEAR B-CELL EPITOPE PREDICTION

AbstractMotivationBy binding to specific structures on antigenic proteins, the so-called epitopes, B-cell antibodies can neutralize...

 
 
 

PANGPCR: PREDICTIONS FOR MULTIPLE TARGETS, REPURPOSING AND SIDE EFFECTS

AbstractSummaryDrug discovery targeting G protein-coupled receptors , the largest known class of therapeutic targets, is challenging....

THE VEGA SUITE OF PROGRAMS: AN VERSATILE PLATFORM FOR CHEMINFORMATICS AND DRUG DESIGN PROJECTS

AbstractThe purpose of the paper is to offer an overview of the latest release of the VEGA suite of programs. This software has been...

 
 
 

SMI-BLAST: A NOVEL SUPERVISED SEARCH FRAMEWORK BASED ON PSI-BLAST FOR PROTEIN REMOTE HOMOLOGY DETECTION

AbstractMotivationAs one of the most important and widely used mainstream iterative search tool for protein sequence search, an accurate...

SAIGEGDS - AN EFFICIENT STATISTICAL TOOL FOR LARGE-SCALE PHEWAS WITH MIXED MODELS

AbstractSummaryPhenome-wide association studies are known to be a powerful tool in discovery and replication of genetic association...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Moderna CMO Talks COVID-19 Vaccine at Xcelerate Next Week

Moderna CMO Talks COVID-19 Vaccine at Xcelerate Next Week

The Xcelerate Keynote Series has added Moderna CMO Tal Zaks to the expert lineup of speakers set to present next Monday, Sept. 21. As you likely know, Moderna is one of the... Read more ...

Securely Emerging into the Quality Nebula

Securely Emerging into the Quality Nebula

Our Software Solutions Quality Document Management Success Written by: Candice Snine, Business Development Manager, PSC Biotech Quality Management in any industry is all about... Read more ...

BIO Chief: “Reckless” Executive Order on Drug Prices Threatens Innovation

BIO Chief: “Reckless” Executive Order on Drug Prices Threatens Innovation

The US is doing more in the COVID-19 space than anywhere in the world due to the strength of its innovative ecosystem, says Michelle McMurry-Heath, president & CEO of life... Read more ...

Dyne's Upsized IPO Brings In $233M for Muscle Disorders Drug R&D

Dyne's Upsized IPO Brings In $233M for Muscle Disorders Drug R&D

Dyne Therapeutics, a company developing genetic medicines for rare muscular disorders, has raised $233 million in an IPO that topped the preclinical-stage biotech's... Read more ...

Finch Therapeutics Fetches $90M to Advance Microbiome Drug Pipeline

Finch Therapeutics Fetches $90M to Advance Microbiome Drug Pipeline

When Seres Therapeutics reported positive late-stage data for its experimental microbiome treatment last month, scientists at Finch Therapeutics cheered the results from the... Read more ...

How SARS-CoV-2 Went from Single Cases to Overwhelming Continents

How SARS-CoV-2 Went from Single Cases to Overwhelming Continents

Early detection and intervention stanched the first known introductions of the SARS-CoV-2 virus into North America and Europe, validating the effectiveness of quick... Read more ...

Arrowhead Pharma Shares Soar on Early Liver Data for RNAi Drug

Arrowhead Pharma Shares Soar on Early Liver Data for RNAi Drug

An Arrowhead Pharmaceuticals drug for a rare liver disease now has early Phase 2 results and the data so far look good. Not only did the therapy reduce levels of a mutant... Read more ...

Easy and Affordable: Full-Length 16S HiFi Sequencing with PacBio Service...

Easy and Affordable: Full-Length 16S HiFi Sequencing with PacBio Service Providers

Analysis of 16S ribosomal RNA has been used for phylogenetics and identifying prokaryotes for decades. But just as scientists have had to refine the Linnaean taxonomy system... Read more ...

Chromatin regulates expression of small RNAs to help maintain transposon...

Eukaryotic genomes are partitioned into euchromatic and heterochromatic domains to regulate gene expression and other fundamental cellular processes. However, chromatin is... Read more ...

Removing reference bias and improving indel calling in ancient DNA data...

During the last decade, the analysis of ancient DNA sequence has become a powerful tool for the study of past human populations. However, the degraded nature of aDNA means that... Read more ...