COMEBACK: DNA METHYLATION ARRAY DATA ANALYSIS FOR CO-METHYLATED REGIONS

AbstractMotivationHigh-dimensional DNA methylation array coverage, while sparse in the context of the entire DNA methylome, still constitutes...

THE FEATURE VIEWER: A VISUALIZATION TOOL FOR POSITIONAL ANNOTATIONS ON A SEQUENCE

AbstractSummaryThe Feature-Viewer is a lightweight library for the visualization of biological data mapped to a protein or nucleotide...

 
 
 

INTEGRATIVE ANALYSIS OF CROSS-MODAL FEATURES FOR THE PROGNOSIS PREDICTION OF CLEAR CELL RENAL CELL CARCINOMA

AbstractMotivationAs a highly heterogeneous disease, clear cell renal cell carcinoma has quite variable clinical behaviors. The prognostic...

ON THE BIAS OF H-SCORES FOR COMPARING BICLUSTERS, AND HOW TO CORRECT IT

Supplementary informationSupplementary materialSupplementary material is available at Bioinformatics online.

 
 
 

IPAC: A GENOME-GUIDED ASSEMBLER OF ISOFORMS VIA PHASING AND COMBING PATHS

AbstractMotivationFull-length transcript reconstruction is very important and quite challenging for the widely used RNA-seq data analysis....

G4KILLER WEB APPLICATION: A TOOL TO DESIGN G-QUADRUPLEX MUTATIONS

AbstractMotivationG-quadruplexes are important regulatory non-B DNA structures with therapeutic potential. A tool for rational design...

 
 
 

BIVARTECT: ACCURATE AND MEMORY-SAVING BREAKPOINT DETECTION BY DIRECT READ COMPARISON

AbstractMotivationGenetic variant calling with high-throughput sequencing data has been recognized as a useful tool for better understanding...

UMI-VARCAL: A NEW UMI-BASED VARIANT CALLER THAT EFFICIENTLY IMPROVES LOW-FREQUENCY VARIANT DETECTION IN PAIRED-END SEQUENCING NGS LIBRARIES

AbstractMotivationNext Generation Sequencing has become the go-to standard method for the detection of Single Nucleotide Variants in...

 
 
 

CONSENSUS FEATURES NESTED CROSS-VALIDATION

AbstractMotivationFeature selection can improve the accuracy of machine learning models, but appropriate steps must be taken to avoid...

CIRCMETA: A UNIFIED COMPUTATIONAL FRAMEWORK FOR GENOMIC FEATURE ANNOTATION AND DIFFERENTIAL EXPRESSION ANALYSIS OF CIRCULAR RNAS

AbstractMotivationCircular RNAs , a class of non-coding RNAs generated from non-canonical back-splicing events, have emerged to play...

 
 
 

GWASRAPIDD: AN R PACKAGE TO QUERY, DOWNLOAD AND WRANGLE GWAS CATALOG DATA

AbstractMotivationThe National Human Genome Research Institute Catalog of Published Genome-Wide Association Studies Catalog has collected,...

PREDICTING THE EFFECTS OF SNPS ON TRANSCRIPTION FACTOR BINDING AFFINITY

AbstractMotivationGenome-wide association studies have revealed that 88% of disease-associated single-nucleotide polymorphisms reside...

 
 
 

DNA RCHITECT: AN R BASED VISUALIZER FOR NETWORK ANALYSIS OF CHROMATIN INTERACTION DATA

AbstractMotivationVisualization of multiple genomic data generally requires the use of public or commercially hosted browsers. Flexible...

RAG-WEB: RNA STRUCTURE PREDICTION/DESIGN USING RNA-AS-GRAPHS

AbstractSummaryWe launch a webserver for RNA structure prediction and design corresponding to tools developed using our RNA-As-Graphs...

 
 
 

ARTIFUSE-COMPUTATIONAL VALIDATION OF FUSION GENE DETECTION TOOLS WITHOUT RELYING ON SIMULATED READS

AbstractMotivationGene fusions are an important class of transcriptional variants that can influence cancer development and can be...

TOPOLOGY-INDEPENDENT AND GLOBAL PROTEIN STRUCTURE ALIGNMENT THROUGH AN FFT-BASED ALGORITHM

AbstractMotivationProtein structure alignment is one of the fundamental problems in computational structure biology. A variety of algorithms...

 
 
 

CONTEXT AWARENESS AND EMBEDDING FOR BIOMEDICAL EVENT EXTRACTION

AbstractMotivationBiomedical event extraction is fundamental for information extraction in molecular biology and biomedical research....

MOOMIN - MATHEMATICAL EXPLORATION OF 'OMICS DATA ON A METABOLIC NETWORK

AbstractMotivationAnalysis of differential expression of genes is often performed to understand how the metabolic activity of an organism...

 
 
 

TOWARD PERFECT READS: SELF-CORRECTION OF SHORT READS VIA MAPPING ON DE BRUIJN GRAPHS

Bioinformatics (2019) doi: 10.1093/bioinformatics/btz102

TRANSCOMPP: UNDERSTANDING PHENOTYPIC PLASTICITY BY ESTIMATING MARKOV TRANSITION RATES FOR CELL STATE TRANSITIONS

AbstractMotivationGradual population-level changes in tissues can be driven by stochastic plasticity, meaning rare stochastic transitions...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Allergan Offloads Two Drugs to Secure Approval of Merger With AbbVie

Allergan Offloads Two Drugs to Secure Approval of Merger With AbbVie

Allergan is selling off an experimental drug and a commercialized product in order to allay antitrust concerns from regulators reviewing the company's $63 billion acquisition... Read more ...

Flagship Adds Fertility-Focused Ohana Biosciences to Biotech Family

Flagship Adds Fertility-Focused Ohana Biosciences to Biotech Family

About 7 million couples in the US have difficulty getting or staying pregnant. A new biotech is using insights into the biology of male reproductive cells-the sperm that must... Read more ...

Quench Bio Springs From Atlas With $50M for a New Take on Inflammation

Quench Bio Springs From Atlas With $50M for a New Take on Inflammation

Cells die all the time in a controlled manner that's perfectly normal. But the way cells die matters. Sometimes cell death is violent, sparking inflammation believed to... Read more ...

When Snakes Strike: SMRT Sequencing Reveals Hidden “Venom-ome”

When Snakes Strike: SMRT Sequencing Reveals Hidden “Venom-ome”

A team of scientists from SciGenom Research Foundation in India has assembled the genome and transcriptome of the lethal Indian Cobra using PacBio long-read sequencing Snake... Read more ...

Life Sciences IPOs Target Collective Raise of More Than $600M This Week

Life Sciences IPOs Target Collective Raise of More Than $600M This Week

So far this year four privately held companies have made the transition to trading on the public markets. By month's end, five more are anticipated to join the class of 2020... Read more ...

Project Manager - Beyond The Clock Solutions - San Diego, CA

Provide management and leadership skills to drive execution on project goals. 3+ years of experience as a project manager, within Pharma/Biopharma, Medical... $35 - $50 an... Read more ...

Sorrento Therapeutics rejects $1 billion buyout offer

San Diego company says offer undervalues the company; updates progress on novel pain management therapies... Read more ...

Shipping and Fulfillment Clerk - Gateway Genomics - La Jolla, CA

We are a boutique and innovative biotech company with a fun, friendly and motivational atmosphere. Gateway Genomics is seeking a motivated individual to join...From Indeed... Read more ...

103598 Radiologic Technician - Per Diem

SURGERY Salary commensurate with qualifications and experienceFiling Deadline: Mon 2/10/2020... Read more ...

Getting to the root of plant survival

When facing a volatile climate, nature searches for a way to survive. For plants, that often means spreading new roots deeper and wider in search of water, particularly in... Read more ...