CLINICAL FEASIBILITY AND BENEFITS OF A TAPERED, SAND-BLASTED, AND ACID-ETCHED SURFACED TISSUE-LEVEL DENTAL IMPLANT

Abstract Background It has been 50 years since Brånemark first introduced the concept of osseointegration. Since then, numerous ongoing...

LONG NONCODING RNAS: EMERGING ROLES IN PULMONARY HYPERTENSION

Abstract Pulmonary hypertension is a complex and progressive disease characterized by increased pulmonary vascular resistance and pulmonary...

 
 
 

IDENTIFICATION AND CHARACTERIZATION OF A TRANSIENT RECEPTOR POTENTIAL ION CHANNEL INVOLVED IN ACCLIMATION TO LOW CO 2 CONDITIONS IN CHLAMYDOMONAS REINHARDTII

Abstract The CO 2 concentrating mechanism is a key feature of green algal cells, induced in response to limiting CO 2 conditions. Calcium-dependent...

TRANSCRIPTOMIC RESPONSE OF IN VITRO POTATO TO PIEZOELECTRIC ULTRASOUND

Abstract As part of a wider project to assess the impact of ultrasound on in vitro plant growth, this paper aimed to determine whether...

 
 
 

PREDICTION OF UBIQUITIN LIGASE NRDP1-ASSOCIATED PROTEINS IN GLIOMA DATABASE

Abstract The ubiquitin proteasome pathway is conserved from yeast to mammals and is necessary for the targeted degradation of most...

THE REGULATORY ROLE OF MIRNAS IN ETHANOL-INDUCED TLR4 ACTIVATION AND NEUROINFLAMMATION

Abstract Purpose of Review Alcohol is a neurotoxic compound and its abuse can induce brain damage and neurodegeneration. Evidence from...

 
 
 

DYNAMIC CHANGE OF SHANKS GENE MRNA EXPRESSION AND DNA METHYLATION IN EPILEPTIC RAT MODEL AND HUMAN PATIENTS

Abstract Synaptic protein shanks (SH3 and multiple ankyrin repeat domains protein, Shank) have emerged as an important mediator of...

POTENTIAL MOLECULAR MECHANISM AND BIOMARKER INVESTIGATION FOR SPINAL CORD INJURY BASED ON BIOINFORMATICS ANALYSIS

Abstract This study aimed to explore the detailed molecular mechanism and biomarkers in spinal cord injury. Gene expression profiles...

 
 
 

COMBINED CRYSTAL PLASTICITY SIMULATIONS AND EXPERIMENTS FOR PARAMETER IDENTIFICATION: APPLICATION TO NEAR- Β TITANIUM ALLOY

Abstract In this work, the crystal plasticity finite element simulations and experiments of nanoindentation and tensile tests are conducted...

RECONFIGURABLE AND TUNABLE PHOTO-CONTROLLED HYDROGEL USING HYDROGEN BONDING TO DRIVE MOLECULE SELF-ASSEMBLY AND CROSS-LINKING

Abstract Reconfigurable micro-nanostructures have been largely used in the development of modern photocontrol technology. In this work,...

 
 
 

ULTRASOUND FREQUENCY-DEPENDENT MICROSTRUCTURES OF ELECTRODEPOSITED NI NANOCRYSTALS FOR MODIFYING MECHANICAL PROPERTIES

Abstract Since it offers high specific strength and superior corrosion resistance, nanocrystalline Ni deposits have attracted much...

KNOCKDOWN OF LONG NON-CODING RNA TUG1 DEPRESSES APOPTOSIS OF HIPPOCAMPAL NEURONS IN ALZHEIMER'S DISEASE BY ELEVATING MICRORNA-15A AND REPRESSING ROCK1 EXPRESSION

Abstract Objective Many studies have already suggested the role of long non-coding RNAs in Alzheimer's disease , but the functions...

 
 
 

EMBRYONIC GENE EXPRESSION ALTERED BY MATERNAL EXPOSURE TO AIR POLLUTION IN RATS

Abstract Exposure to air pollution is known to increase the risks for cardiovascular, pulmonary and metabolic diseases. Growing evidences...

A STUDY ON METAHEURISTICS APPROACHES FOR GENE SELECTION IN MICROARRAY DATA: ALGORITHMS, APPLICATIONS AND OPEN CHALLENGES

Abstract In the recent decades, researchers have introduced an abundance of feature selection methods many of which are studied and...

 
 
 

A PARALLEL CLASSIFICATION FRAMEWORK FOR PROTEIN FOLD RECOGNITION

Abstract Proteins' tertiary structure, which is determined by its amino acid sequence via the protein folding process, have essential...

MICRORNA-127-3P REGULATES MYOBLAST PROLIFERATION BY TARGETING SEPT7

Abstract Objective MicroRNAs are highly conserved, endogenous small RNAs that regulate gene expression at the post-transcriptional...

 
 
 

A REVIEW OF CRISPR ASSOCIATED GENOME ENGINEERING: APPLICATION, ADVANCES AND FUTURE PROSPECTS OF GENOME TARGETING TOOL FOR CROP IMPROVEMENT

Abstract The Cas9 nuclease initiates double-stranded breaks at the target position in DNA, which are repaired by the intracellular...

PIERCE INTO THE NATIVE STRUCTURE OF ATA, A TRIMERIC AUTOTRANSPORTER OF ACINETOBACTER BAUMANNII ATCC 17978

Abstract Acinetobacter baumannii is an important pathogen responsible for nosocomial infections worldwide. Trimeric autotransporters,...

 
 
 

PROSPECTIVE AVENUES FOR HUMAN POPULATION GENOMICS AND DISEASE MAPPING IN SOUTHERN AFRICA

Abstract Population substructure within human populations is globally evident and a well-known confounding factor in many genetic studies....

IDENTIFICATION OF DRUG AND VACCINE TARGET IN MYCOBACTERIUM LEPRAE: A REVERSE VACCINOLOGY APPROACH

Abstract Mycobacterium leprae , an infectious agent of chronic infection so-called Leprosy. It is a prime healthconcern in various...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

GentiBio Joins Cell Therapy Chase With $20M and New Treg Technology

GentiBio Joins Cell Therapy Chase With $20M and New Treg Technology

One of the challenges facing cell therapy developers is collecting enough cells to produce a viable treatment. It's a particularly pronounced problem for therapies employing... Read more ...

AbbVie Walks From Voyager R&D Pact Spanning Alzheimer's, Parkinson's

AbbVie Walks From Voyager R&D Pact Spanning Alzheimer's, Parkinson's

A partnership between Voyager Therapeutics and AbbVie developing gene therapies for Alzheimer's and Parkinson's has ended without a drug for either disease reaching human... Read more ...

Interpreting the Human Genome's Instruction Manual

Interpreting the Human Genome's Instruction Manual

An artistic representation of gene regulating elements, which allow cells with the same genetic code to differentiate into many different tissues and play many varied roles in... Read more ...

IgGenix Grabs $10M to Advance Antibody Treatments for Allergies

IgGenix Grabs $10M to Advance Antibody Treatments for Allergies

About six months after the FDA approved the first treatment for peanut allergy, a new biotech, IgGenix, has raised $10 million to discover antibodies that could address that... Read more ...

As Patients Pivot to Telehealth, Teladoc & Livongo Plan $18.5B Tie-Up

As Patients Pivot to Telehealth, Teladoc & Livongo Plan $18.5B Tie-Up

Telemedicine giant Teladoc Health is buying health technology company Livongo Health in an $18.5 billion cash and stock deal that comes as the COVID-19 pandemic drives patients... Read more ...

Kristin Persson Named Director of Berkeley Lab's Molecular Foundry

Kristin Persson Named Director of Berkeley Lab's Molecular Foundry

Kristin Persson Kristin Persson, a senior faculty scientist in the Energy Storage & Distributed Resources Division within the Energy Technologies Area at Lawrence Berkeley... Read more ...

Geothermal Brines Could Propel California's Green Economy

Geothermal Brines Could Propel California's Green Economy

Thermal mud pots at Controlled Thermal Resources' project site at the Salton Sea. Deep beneath the surface of the Salton Sea, a shallow lake in California's Imperial County... Read more ...

Still Stuck on Adhesion Issues, FDA Rejects DBV's Peanut Allergy Patch

Still Stuck on Adhesion Issues, FDA Rejects DBV's Peanut Allergy Patch

A skin patch developed by DBV Technologies to desensitize peanut allergy sufferers to the allergen over time has been rejected by the FDA, which says the French company needs... Read more ...

CymaBay PBC Drug Hits Phase 3 Goals With Signs of Side Effect Advantage

CymaBay PBC Drug Hits Phase 3 Goals With Signs of Side Effect Advantage

CymaBay Therapeutics' investigational drug seladelpar succeeded in a late-stage trial in patients with primary biliary cholangitis , producing results that suggest it could... Read more ...

PDR: a new genome assembly evaluation metric based on genetics concerns

AbstractMotivationExisting genome assembly evaluation metrics provide only limited insight on specific aspects of genome assembly quality, and sometimes even disagree with each... Read more ...